MOUSE:MMP9

Species (Taxon ID)	Mus musculus (Mouse). (10090)
Gene Name(s)	Mmp9 (synonyms: Clg4b)
Protein Name(s)	Matrix metalloproteinase-9 MMP-9 92 kDa gelatinase 92 kDa type IV collagenase Gelatinase B GELB
External Links
UniProt	P41245
EMBL	D12712 S67830 X72794 X72795 Z27231 AK004651 AK159292 AL591495 BC046991
CCDS	CCDS17066.1
PIR	I52580 JC1456
RefSeq	NP_038627.1
UniGene	Mm.4406
ProteinModelPortal	P41245
SMR	P41245
BioGrid	201454
STRING	10090.ENSMUSP00000017881
BindingDB	P41245
ChEMBL	CHEMBL2214
MEROPS	M10.004
PhosphoSite	P41245
MaxQB	P41245
PaxDb	P41245
PRIDE	P41245
Ensembl	ENSMUST00000017881
GeneID	17395
KEGG	mmu:17395
UCSC	uc008nwt.2
CTD	4318
MGI	MGI:97011
eggNOG	KOG1565 ENOG410XQ5D
GeneTree	ENSGT00830000128254
HOGENOM	HOG000217926
HOVERGEN	HBG052484
InParanoid	P41245
KO	K01403
OMA	GFCPSER
OrthoDB	EOG70KGNX
TreeFam	TF315428
BRENDA	3.4.24.35
Reactome	[www.reactome.org/content/detail/R-MMU-1433557 R-MMU-1433557] [www.reactome.org/content/detail/R-MMU-1442490 R-MMU-1442490] [www.reactome.org/content/detail/R-MMU-1474228 R-MMU-1474228] [www.reactome.org/content/detail/R-MMU-1592389 R-MMU-1592389] [www.reactome.org/content/detail/R-MMU-2022090 R-MMU-2022090] [www.reactome.org/content/detail/R-MMU-3928665 R-MMU-3928665]
PRO	PR:P41245
Proteomes	UP000000589
Bgee	P41245
CleanEx	MM_MMP9
ExpressionAtlas	P41245
Genevisible	P41245
GO	GO:0070062 GO:0005615 GO:0005578 GO:0004175 GO:0042802 GO:0004222 GO:0008237 GO:0008233 GO:0008270 GO:0030574 GO:0007566 GO:0035987 GO:0030198 GO:0050900 GO:0043066 GO:2001258 GO:2001268 GO:2001243 GO:0001503 GO:0043065 GO:0043388 GO:0045742 GO:0051549 GO:0001934 GO:1900122 GO:0090200 GO:0006508 GO:0001501
Gene3D	2.10.10.10 2.110.10.10 3.40.390.10
InterPro	IPR000562 IPR000585 IPR018487 IPR018486 IPR013806 IPR024079 IPR028688 IPR001818 IPR021190 IPR021158 IPR006026 IPR002477 IPR006970
PANTHER	PTHR10201:SF30
Pfam	PF00040 PF00045 PF00413 PF01471 PF04886
PRINTS	PR00138
SMART	SM00059 SM00120 SM00235
SUPFAM	SSF47090 SSF50923 SSF57440
PROSITE	PS00546 PS00023 PS51092 PS00024 PS51642 PS00142

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
part_of	GO:0062023	collagen-containing extracellular matrix	PMID:22159717^[1]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C	part_of:(UBERON:0002048)	Seeded From UniProt	complete
involved_in	GO:1904645	response to amyloid-beta	PMID:28912710^[2]	ECO:0000314	direct assay evidence used in manual assertion		P	occurs_in:(CL:0000129)	Seeded From UniProt	complete
involved_in	GO:2000697	negative regulation of epithelial cell differentiation involved in kidney development	PMID:24503540^[3]	ECO:0000314	direct assay evidence used in manual assertion		P	occurs_in:(CL:0002570)	Seeded From UniProt	complete
enables	GO:0008237	metallopeptidase activity	PMID:15851690^[4]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0006508	proteolysis	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P14780	P		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P14780	C		Seeded From UniProt	complete
enables	GO:0004222	metalloendopeptidase activity	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P14780	F		Seeded From UniProt	complete
involved_in	GO:0030574	collagen catabolic process	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:101900 MGI:MGI:1276107 MGI:MGI:1340026 MGI:MGI:97008 MGI:MGI:97009 MGI:MGI:97011 PANTHER:PTN001303987 RGD:621316 RGD:621320 UniProtKB:P45452	P		Seeded From UniProt	complete
involved_in	GO:0030198	extracellular matrix organization	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0033438 FB:FBgn0035049 MGI:MGI:1340026 MGI:MGI:1353466 MGI:MGI:97008 MGI:MGI:97011 PANTHER:PTN001303987 UniProtKB:P45452 WB:WBGene00006987 ZFIN:ZDB-GENE-040426-2132	P		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97005 MGI:MGI:97009 PANTHER:PTN000810753 RGD:3100 RGD:620196 RGD:621316 RGD:621317 RGD:621320 RGD:631408 UniProtKB:B5DFD5 UniProtKB:P02790 UniProtKB:P08253 UniProtKB:P14780 UniProtKB:P22894 UniProtKB:P39900 UniProtKB:P50281 UniProtKB:Q90611	C		Seeded From UniProt	complete
enables	GO:0004222	metalloendopeptidase activity	PMID:21873635^[5]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0033438 MGI:MGI:101900 MGI:MGI:1340026 MGI:MGI:1341867 MGI:MGI:97009 MGI:MGI:97011 PANTHER:PTN001303987 RGD:620196 TAIR:locus:2020548 TAIR:locus:2025891 TAIR:locus:2032467 TAIR:locus:2055605 TAIR:locus:2130928 UniProtKB:O60882 UniProtKB:O75900 UniProtKB:P03956 UniProtKB:P14780 UniProtKB:P39900 UniProtKB:P45452 UniProtKB:P51512 UniProtKB:Q90611 UniProtKB:Q99542	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:2001268	negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P14780	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:2001258	negative regulation of cation channel activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P14780	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P14780	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:1904707	positive regulation of vascular smooth muscle cell proliferation	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P14780	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:1900122	positive regulation of receptor binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P14780	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0090200	positive regulation of release of cytochrome c from mitochondria	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P14780	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0071460	cellular response to cell-matrix adhesion	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:621320	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0071276	cellular response to cadmium ion	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P14780	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0051549	positive regulation of keratinocyte migration	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P14780	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0051259	protein complex oligomerization	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:621320	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0048771	tissue remodeling	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:621320	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0048147	negative regulation of fibroblast proliferation	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:621320	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045766	positive regulation of angiogenesis	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:621320	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P14780	P		Seeded From UniProt	complete
enables	GO:0044877	protein-containing complex binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:621320	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0043388	positive regulation of DNA binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P14780	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0043066	negative regulation of apoptotic process	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P14780	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0043065	positive regulation of apoptotic process	PMID:15800063^[6]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:1932294	P	occurs_in:(EMAPA:36159) regulates_o_occurs_in:(CL:0000743)	Seeded From UniProt	complete
enables	GO:0042802	identical protein binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P14780	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0042493	response to drug	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:621320	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0034614	cellular response to reactive oxygen species	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P14780	P		Seeded From UniProt	complete
part_of	GO:0032991	protein-containing complex	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:621320	C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0031915	positive regulation of synaptic plasticity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:621320	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0030574	collagen catabolic process	PMID:9291580^[7]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0030574	collagen catabolic process	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:621320	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0030335	positive regulation of cell migration	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P14780	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0030198	extracellular matrix organization	PMID:15800063^[6]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:96778	P	occurs_in:(EMAPA:36159)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0030198	extracellular matrix organization	PMID:15800063^[6]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:1932294	P	occurs_in:(EMAPA:36159)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0019087	transformation of host cell by virus	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:621320	P		Seeded From UniProt	complete
enables	GO:0008237	metallopeptidase activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P14780	F		Seeded From UniProt	complete
enables	GO:0008237	metallopeptidase activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:621320	F		Seeded From UniProt	complete
enables	GO:0008233	peptidase activity	PMID:15800063^[6]	ECO:0000314	direct assay evidence used in manual assertion		F	has_direct_input:(MGI:MGI:96778)	Seeded From UniProt	complete
enables	GO:0008233	peptidase activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:621320	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007568	aging	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:621320	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007566	embryo implantation	PMID:18556655^[8]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007507	heart development	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:621320	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0006979	response to oxidative stress	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:621320	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0006508	proteolysis	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P14780	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0006508	proteolysis	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:621320	P		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P14780	C		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:621320	C		Seeded From UniProt	complete
enables	GO:0004252	serine-type endopeptidase activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P14780	F		Seeded From UniProt	complete
enables	GO:0004222	metalloendopeptidase activity	PMID:9291580^[7]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0004222	metalloendopeptidase activity	PMID:14707083^[9]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0004222	metalloendopeptidase activity	PMID:12419962^[10]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0004222	metalloendopeptidase activity	GO_REF:0000008	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P14780	F		Seeded From UniProt	complete
enables	GO:0004175	endopeptidase activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P14780	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0002687	positive regulation of leukocyte migration	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:621320	P		Seeded From UniProt	complete
enables	GO:0001968	fibronectin binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:621320	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0001934	positive regulation of protein phosphorylation	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P14780	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0001501	skeletal system development	PMID:15800063^[6]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:96778	P	results_in_development_of:(EMAPA:36159)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0001501	skeletal system development	PMID:15800063^[6]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:1932294	P	results_in_development_of:(EMAPA:36159)	Seeded From UniProt	complete
involved_in	GO:2001268	negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14780 ensembl:ENSP00000361405	P		Seeded From UniProt	complete
involved_in	GO:2001258	negative regulation of cation channel activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14780 ensembl:ENSP00000361405	P		Seeded From UniProt	complete
involved_in	GO:2001243	negative regulation of intrinsic apoptotic signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14780 ensembl:ENSP00000361405	P		Seeded From UniProt	complete
involved_in	GO:1904707	positive regulation of vascular smooth muscle cell proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14780 ensembl:ENSP00000361405	P		Seeded From UniProt	complete
involved_in	GO:1900122	positive regulation of receptor binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14780 ensembl:ENSP00000361405	P		Seeded From UniProt	complete
involved_in	GO:0090200	positive regulation of release of cytochrome c from mitochondria	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14780 ensembl:ENSP00000361405	P		Seeded From UniProt	complete
involved_in	GO:0071276	cellular response to cadmium ion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14780 ensembl:ENSP00000361405	P		Seeded From UniProt	complete
involved_in	GO:0051549	positive regulation of keratinocyte migration	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14780 ensembl:ENSP00000361405	P		Seeded From UniProt	complete
involved_in	GO:0045742	positive regulation of epidermal growth factor receptor signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14780 ensembl:ENSP00000361405	P		Seeded From UniProt	complete
involved_in	GO:0043388	positive regulation of DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14780 ensembl:ENSP00000361405	P		Seeded From UniProt	complete
involved_in	GO:0043066	negative regulation of apoptotic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14780 ensembl:ENSP00000361405	P		Seeded From UniProt	complete
enables	GO:0042802	identical protein binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14780 ensembl:ENSP00000361405	F		Seeded From UniProt	complete
involved_in	GO:0035987	endodermal cell differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14780 ensembl:ENSP00000361405	P		Seeded From UniProt	complete
involved_in	GO:0034614	cellular response to reactive oxygen species	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14780 ensembl:ENSP00000361405	P		Seeded From UniProt	complete
involved_in	GO:0030335	positive regulation of cell migration	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14780 ensembl:ENSP00000361405	P		Seeded From UniProt	complete
enables	GO:0008237	metallopeptidase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14780 ensembl:ENSP00000361405	F		Seeded From UniProt	complete
involved_in	GO:0006508	proteolysis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14780 ensembl:ENSP00000361405	P		Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14780 ensembl:ENSP00000361405	C		Seeded From UniProt	complete
enables	GO:0004222	metalloendopeptidase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14780 ensembl:ENSP00000361405	F		Seeded From UniProt	complete
enables	GO:0004175	endopeptidase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14780 ensembl:ENSP00000361405	F		Seeded From UniProt	complete
involved_in	GO:0001934	positive regulation of protein phosphorylation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P14780 ensembl:ENSP00000361405	P		Seeded From UniProt	complete
involved_in	GO:0001503	ossification	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR028688	P		Seeded From UniProt	complete
enables	GO:0004222	metalloendopeptidase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001818 InterPro:IPR021158 InterPro:IPR021190 InterPro:IPR028688	F		Seeded From UniProt	complete
involved_in	GO:0006508	proteolysis	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001818 InterPro:IPR006026 InterPro:IPR021158 InterPro:IPR021190 InterPro:IPR028688	P		Seeded From UniProt	complete
enables	GO:0008237	metallopeptidase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR006026 InterPro:IPR024079 InterPro:IPR033739	F		Seeded From UniProt	complete
enables	GO:0008270	zinc ion binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001818 InterPro:IPR006026 InterPro:IPR021158 InterPro:IPR021190 InterPro:IPR033739	F		Seeded From UniProt	complete
involved_in	GO:0030574	collagen catabolic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR028688	P		Seeded From UniProt	complete
part_of	GO:0031012	extracellular matrix	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001818 InterPro:IPR021158 InterPro:IPR021190	C		Seeded From UniProt	complete
involved_in	GO:0050900	leukocyte migration	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR028688	P		Seeded From UniProt	complete
part_of	GO:0005576	extracellular region	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0964	C		Seeded From UniProt	complete
enables	GO:0016787	hydrolase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0378	F		Seeded From UniProt	complete
enables	GO:0008237	metallopeptidase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0482	F		Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F		Seeded From UniProt	complete
enables	GO:0008233	peptidase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0645	F		Seeded From UniProt	complete
involved_in	GO:0006508	proteolysis	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0645	P		Seeded From UniProt	complete
involved_in	GO:0030574	collagen catabolic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0177	P		Seeded From UniProt	complete
edit table

Notes

References

See Help:References for how to manage references in GONUTS.

↑ Naba, A et al. (2012) The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices. Mol. Cell Proteomics 11 M111.014647 PubMed GONUTS page
↑ Caldeira, C et al. (2017) Key Aging-Associated Alterations in Primary Microglia Response to Beta-Amyloid Stimulation. Front Aging Neurosci 9 277 PubMed GONUTS page
↑ Ventayol, M et al. (2014) miRNA let-7e targeting MMP9 is involved in adipose-derived stem cell differentiation toward epithelia. Cell Death Dis 5 e1048 PubMed GONUTS page
↑ Park, SG et al. (2005) Human lysyl-tRNA synthetase is secreted to trigger proinflammatory response. Proc. Natl. Acad. Sci. U.S.A. 102 6356-61 PubMed GONUTS page
↑ ^5.0 ^5.1 ^5.2 ^5.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ ^6.0 ^6.1 ^6.2 ^6.3 ^6.4 ^6.5 Ortega, N et al. (2005) Galectin-3 is a downstream regulator of matrix metalloproteinase-9 function during endochondral bone formation. Mol. Biol. Cell 16 3028-39 PubMed GONUTS page
↑ ^7.0 ^7.1 Leco, KJ et al. (1997) Matrix metalloproteinase-9 maps to the distal end of chromosome 2 in the mouse. Dev. Genet. 21 55-60 PubMed GONUTS page
↑ Hu, SJ et al. (2008) MicroRNA expression and regulation in mouse uterus during embryo implantation. J. Biol. Chem. 283 23473-84 PubMed GONUTS page
↑ Webb, DC et al. (2004) Polymorphisms in IL-4R alpha correlate with airways hyperreactivity, eosinophilia, and Ym protein expression in allergic IL-13-/- mice. J. Immunol. 172 1092-8 PubMed GONUTS page
↑ Minamitani, T et al. (2002) Adhesive defect in extracellular matrix tenascin-X-null fibroblasts: a possible mechanism of tumor invasion. Biol. Pharm. Bull. 25 1472-5 PubMed GONUTS page

[PMID:22159717-1] Naba, A et al. (2012) The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices. Mol. Cell Proteomics 11 M111.014647 PubMed GONUTS page

[PMID:28912710-2] Caldeira, C et al. (2017) Key Aging-Associated Alterations in Primary Microglia Response to Beta-Amyloid Stimulation. Front Aging Neurosci 9 277 PubMed GONUTS page

[PMID:24503540-3] Ventayol, M et al. (2014) miRNA let-7e targeting MMP9 is involved in adipose-derived stem cell differentiation toward epithelia. Cell Death Dis 5 e1048 PubMed GONUTS page

[PMID:15851690-4] Park, SG et al. (2005) Human lysyl-tRNA synthetase is secreted to trigger proinflammatory response. Proc. Natl. Acad. Sci. U.S.A. 102 6356-61 PubMed GONUTS page

[PMID:21873635-5] 5.0 ^5.1 ^5.2 ^5.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:15800063-6] 6.0 ^6.1 ^6.2 ^6.3 ^6.4 ^6.5 Ortega, N et al. (2005) Galectin-3 is a downstream regulator of matrix metalloproteinase-9 function during endochondral bone formation. Mol. Biol. Cell 16 3028-39 PubMed GONUTS page

[PMID:9291580-7] 7.0 ^7.1 Leco, KJ et al. (1997) Matrix metalloproteinase-9 maps to the distal end of chromosome 2 in the mouse. Dev. Genet. 21 55-60 PubMed GONUTS page

[PMID:18556655-8] Hu, SJ et al. (2008) MicroRNA expression and regulation in mouse uterus during embryo implantation. J. Biol. Chem. 283 23473-84 PubMed GONUTS page

[PMID:14707083-9] Webb, DC et al. (2004) Polymorphisms in IL-4R alpha correlate with airways hyperreactivity, eosinophilia, and Ym protein expression in allergic IL-13-/- mice. J. Immunol. 172 1092-8 PubMed GONUTS page

[PMID:12419962-10] Minamitani, T et al. (2002) Adhesive defect in extracellular matrix tenascin-X-null fibroblasts: a possible mechanism of tumor invasion. Biol. Pharm. Bull. 25 1472-5 PubMed GONUTS page

[1]

[2]

[3]

[4]

[5]

[6]

[7]

[8]

[9]

[10]

MOUSE:MMP9

Contents

Annotations

Notes

References

c

e

f

g

h

i

l

m

n

o

p

r

s

t

v

z

Navigation menu

Personal tools

Namespaces

Variants

Views

More

Search

Navigation

Cacao

Links

Tools