Category:GO:0004252 ! serine-type endopeptidase activity

name: serine-type endopeptidase activity
namespace: molecular_function
def: "Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine)." [GOC:mah, https://www.ebi.ac.uk/merops/about/glossary.shtml#CATTYPE]
subset: goslim_chembl
synonym: "blood coagulation factor activity" RELATED []
synonym: "serine elastase activity" RELATED [GOC:krc]
xref: EC:3.4.21.-
is_a: GO:0004175 ! endopeptidase activity
is_a: GO:0008236 ! serine-type peptidase activity

AmiGO <GOterm>GO:0004252</GOterm>
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