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GLOHA:VMHA

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Species (Taxon ID) Gloydius halys (Chinese water mocassin) (Agkistrodon halys). (8714)
Gene Name(s) No Information Provided.
Protein Name(s) Zinc metalloprotease-disintegrin halysase
External Links
UniProt Q8AWI5
EMBL AY149647
HSSP P21859
ProteinModelPortal Q8AWI5
SMR Q8AWI5
MEROPS M12.315
HOVERGEN HBG006978
GO GO:0005576
GO:0004222
GO:0008270
GO:0006915
GO:0007596
GO:0006508
Gene3D G3DSA:4.10.70.10
G3DSA:3.40.390.10
InterPro IPR006586
IPR001762
IPR018358
IPR024079
IPR001590
IPR002870
Pfam PF08516
PF00200
PF01562
PF01421
PRINTS PR00289
SMART SM00608
SM00050
SUPFAM SSF57552
PROSITE PS50215
PS00427
PS50214
PS00142

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0072577

endothelial cell apoptosis

PMID:14688240[1]

ECO:0000314

P

Figure 7 shows endothelial cell apoptosis caused by halysase through fluorescence.

complete
CACAO 4033

involved_in

GO:0009405

pathogenesis

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0090729

P

Seeded From UniProt

complete

enables

GO:0004222

metalloendopeptidase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001590

F

Seeded From UniProt

complete

involved_in

GO:0006508

proteolysis

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001590

P

Seeded From UniProt

complete

enables

GO:0008237

metallopeptidase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR024079

F

Seeded From UniProt

complete

enables

GO:0008233

peptidase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0645

F

Seeded From UniProt

complete

enables

GO:0090729

toxin activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0800

F

Seeded From UniProt

complete

involved_in

GO:0006508

proteolysis

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0645

P

Seeded From UniProt

complete

enables

GO:0008237

metallopeptidase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0482

F

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

involved_in

GO:0006915

apoptotic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0053

P

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964
UniProtKB-SubCell:SL-0243

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. You, WK et al. (2003) A novel metalloprotease from Gloydius halys venom induces endothelial cell apoptosis through its protease and disintegrin-like domains. J. Biochem. 134 739-49 PubMed GONUTS page