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STRR6:Q8DNW9

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Species (Taxon ID) Streptococcus pneumoniae (strain ATCC BAA-255 / R6). (171101)
Gene Name(s) pepO (ECO:0000313 with EMBL:AAL00295.1)
Protein Name(s) Endopeptidase O (ECO:0000313 with EMBL:AAL00295.1)
External Links
UniProt Q8DNW9
EMBL AE007317
PIR B98058
RefSeq NP_359084.1
WP_000199272.1
ProteinModelPortal Q8DNW9
STRING 171101.spr1491
MEROPS M13.005
EnsemblBacteria AAL00295
GeneID 933477
KEGG spr:spr1491
PATRIC 19702993
eggNOG COG3590
ENOG4105C9K
HOGENOM HOG000245573
KO K07386
OMA HIGYPEQ
OrthoDB EOG6V7BJT
BioCyc SPNE171101:GJC8-1505-MONOMER
Proteomes UP000000586
GO GO:0004222
Gene3D 3.40.390.10
InterPro IPR024079
IPR000718
IPR018497
IPR008753
PANTHER PTHR11733
Pfam PF01431
PF05649
PRINTS PR00786

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

Contributes to

GO:0098635

protein complex involved in cell-cell adhesion

PMID:23341464[1]

ECO:0000314

C

Figure 9. Charts B, C, and D indicate bacteria lacking PepO gene had significantly less adherence, thus reducing rates of cell invasion and bacteria survival.

complete
CACAO 11348

enables

GO:0004222

metalloendopeptidase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000718
InterPro:IPR018497

F

Seeded From UniProt

complete

involved_in

GO:0006508

proteolysis

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000718
InterPro:IPR008753
InterPro:IPR018497

P

Seeded From UniProt

complete

enables

GO:0008237

metallopeptidase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR024079

F

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Agarwal, V et al. (2013) Streptococcus pneumoniae endopeptidase O (PepO) is a multifunctional plasminogen- and fibronectin-binding protein, facilitating evasion of innate immunity and invasion of host cells. J. Biol. Chem. 288 6849-63 PubMed GONUTS page