GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
MOUSE:ADEC1
Contents
Species (Taxon ID) | Mus musculus (Mouse). (10090) | |
Gene Name(s) | Adamdec1 | |
Protein Name(s) | ADAM DEC1
A disintegrin and metalloproteinase domain-like protein decysin-1 ADAM-like protein decysin-1 | |
External Links | ||
UniProt | Q9R0X2 | |
EMBL | AJ242912 BC046324 | |
CCDS | CCDS49532.1 | |
RefSeq | NP_067450.1 | |
UniGene | Mm.36742 | |
ProteinModelPortal | Q9R0X2 | |
SMR | Q9R0X2 | |
MEROPS | M12.219 | |
PhosphoSite | Q9R0X2 | |
MaxQB | Q9R0X2 | |
PaxDb | Q9R0X2 | |
PRIDE | Q9R0X2 | |
Ensembl | ENSMUST00000022641 | |
GeneID | 58860 | |
KEGG | mmu:58860 | |
UCSC | uc007uls.1 | |
CTD | 27299 | |
MGI | MGI:1917650 | |
eggNOG | NOG280097 | |
GeneTree | ENSGT00760000119181 | |
HOGENOM | HOG000230883 | |
HOVERGEN | HBG106501 | |
InParanoid | Q9R0X2 | |
KO | K08634 | |
OMA | LRGYFTH | |
OrthoDB | EOG7CNZFH | |
PhylomeDB | Q9R0X2 | |
TreeFam | TF314733 | |
NextBio | 314412 | |
PRO | PR:Q9R0X2 | |
Proteomes | UP000000589 | |
Bgee | Q9R0X2 | |
CleanEx | MM_ADAMDEC1 | |
ExpressionAtlas | Q9R0X2 | |
Genevestigator | Q9R0X2 | |
GO | GO:0005576 GO:0004222 GO:0008270 | |
Gene3D | 3.40.390.10 | |
InterPro | IPR001762 IPR024079 IPR001590 IPR002870 | |
Pfam | PF00200 PF01562 PF01421 | |
SMART | SM00050 | |
PROSITE | PS50215 PS50214 PS00142 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
GO:0045589 |
regulation of regulatory T cell differentiation |
ECO:0000315 |
P |
Figure 1. Underexpression of the dec1 gene results in reduced T-regulatory cells, this reduction in T-cell number leads to significant growth defects in lymphatic organs. This results in susceptibility to autoimmune disease and reduction of the body's ability to fight infection and other forms of pathogenesis. |
complete | |||||
part_of |
GO:0005575 |
cellular_component |
ECO:0000307 |
no biological data found used in manual assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0004222 |
metalloendopeptidase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006508 |
proteolysis |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0008237 |
metallopeptidase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0008233 |
peptidase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0008237 |
metallopeptidase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0016787 |
hydrolase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005576 |
extracellular region |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006508 |
proteolysis |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Miyazaki, K et al. (2010) The role of the basic helix-loop-helix transcription factor Dec1 in the regulatory T cells. J. Immunol. 185 7330-9 PubMed GONUTS page