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RABIT:G1SZC8

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Species (Taxon ID) Oryctolagus cuniculus (Rabbit). (9986)
Gene Name(s) ADAM17 (ECO:0000313 with Ensembl:ENSOCUP00000009023)
Protein Name(s) Uncharacterized protein (ECO:0000313 with Ensembl:ENSOCUP00000009023)
External Links
UniProt G1SZC8
ProteinModelPortal G1SZC8
STRING 9986.ENSOCUP00000009023
Ensembl ENSOCUT00000010473
eggNOG KOG3658
ENOG410XQWB
GeneTree ENSGT00670000097974
InParanoid G1SZC8
OMA DQEGFKG
OrthoDB EOG7S4X58
TreeFam TF314733
Proteomes UP000001811
GO GO:0015629
GO:0016324
GO:0009986
GO:0005911
GO:0005737
GO:0005925
GO:0005887
GO:0045121
GO:0032587
GO:0004222
GO:0008270
GO:0033627
GO:0050830
GO:0035625
GO:0030512
GO:0007220
GO:0051088
GO:0030307
GO:0008284
GO:0032722
GO:0031659
GO:0010820
GO:0055099
GO:0001666
GO:0032496
GO:0035313
Gene3D 3.40.390.10
4.10.70.10
InterPro IPR032029
IPR001762
IPR024079
IPR001590
IPR002870
Pfam PF16698
PF00200
PF01562
SMART SM00050
SUPFAM SSF57552
PROSITE PS50215
PS50214

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0061581

corneal epithelial cell migration

PMID:27058125[1]

ECO:0000314

P

Figure 3. shows the ADAM17 activity in unexposed and NM-exposed corneas. Figure 4.B shows the immunofluorescence of corneas using an anti-human ADAM17 ectodomain antibody. This visualizes active ADAM17 immunoreactivity.

complete
CACAO 11838

enables

GO:0004222

metalloendopeptidase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001590

F

Seeded From UniProt

complete

involved_in

GO:0006508

proteolysis

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001590

P

Seeded From UniProt

complete

enables

GO:0008237

metallopeptidase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR024079
InterPro:IPR034025

F

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000038

ECO:0000323

imported automatically asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. DeSantis-Rodrigues, A et al. (2016) ADAM17 Inhibitors Attenuate Corneal Epithelial Detachment Induced by Mustard Exposure. Invest. Ophthalmol. Vis. Sci. 57 1687-1698 PubMed GONUTS page