LEIMA:GP63

Species (Taxon ID)	Leishmania major. (5664)
Gene Name(s)	gp63
Protein Name(s)	Leishmanolysin Cell surface protease Major surface glycoprotein Major surface protease Promastigote surface endopeptidase Protein gp63
External Links
UniProt	P08148
EMBL	Y00647
PIR	PL0221
PDB	1LML
PDBsum	1LML
ProteinModelPortal	P08148
SMR	P08148
MEROPS	M08.001
UniCarbKB	P08148
EvolutionaryTrace	P08148
PMAP-CutDB	P08148
GO	GO:0031225 GO:0005886 GO:0046872 GO:0004222 GO:0007155
InterPro	IPR001577
PANTHER	PTHR10942
Pfam	PF01457
PRINTS	PR00782
PROSITE	PS00142

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
involved_in	GO:0052032	modulation by symbiont of host inflammatory response		ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0036523	positive regulation by symbiont of host cytokine secretion		ECO:0000315	mutant phenotype evidence used in manual assertion		P	has_regulation_target:(UniProtKB:P08505) has_regulation_target:(UniProtKB:P06804)	Seeded From UniProt	complete
involved_in	GO:0052014	catabolism by symbiont of host protein		ECO:0000315	mutant phenotype evidence used in manual assertion		P	has_input:(UniProtKB:Q9R0N3) part_of:(GO:0036523)	Seeded From UniProt	complete
enables	GO:0008237	metallopeptidase activity		ECO:0000315	mutant phenotype evidence used in manual assertion		F	has_input:(UniProtKB:Q9R0N3) part_of:(GO:0052014)	Seeded From UniProt	complete
enables	GO:0004222	metalloendopeptidase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001577	F		Seeded From UniProt	complete
involved_in	GO:0006508	proteolysis	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001577	P		Seeded From UniProt	complete
involved_in	GO:0007155	cell adhesion	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001577	P		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001577	C		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1003 UniProtKB-SubCell:SL-0039	C		Seeded From UniProt	complete
enables	GO:0016787	hydrolase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0378	F		Seeded From UniProt	complete
involved_in	GO:0007155	cell adhesion	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0130	P		Seeded From UniProt	complete
involved_in	GO:0006508	proteolysis	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0645	P		Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F		Seeded From UniProt	complete
enables	GO:0008233	peptidase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0645	F		Seeded From UniProt	complete
part_of	GO:0031225	anchored component of membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0336	C		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C		Seeded From UniProt	complete
enables	GO:0008237	metallopeptidase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0482	F		Seeded From UniProt	complete
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References

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