GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
PSEAE:LASA
Contents
| Species (Taxon ID) | Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 /JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1). (208964) | |
| Gene Name(s) | lasA | |
| Protein Name(s) | Protease LasA
Staphylolytic protease | |
| External Links | ||
| UniProt | P14789 | |
| EMBL | M20982 X55904 U68175 AE004091 | |
| PIR | A46076 F83411 | |
| RefSeq | NP_250562.1 WP_010895585.1 | |
| PDB | 3IT5 3IT7 | |
| PDBsum | 3IT5 3IT7 | |
| ProteinModelPortal | P14789 | |
| SMR | P14789 | |
| STRING | 208964.PA1871 | |
| MEROPS | M23.002 | |
| PaxDb | P14789 | |
| PRIDE | P14789 | |
| EnsemblBacteria | AAG05260 | |
| GeneID | 878260 | |
| KEGG | pae:PA1871 | |
| PATRIC | fig|208964.12.peg.1948 | |
| PseudoCAP | PA1871 | |
| eggNOG | ENOG4108VC8 COG0739 | |
| HOGENOM | HOG000274301 | |
| InParanoid | P14789 | |
| KO | K08642 | |
| OMA | ATNYYHM | |
| BioCyc | PAER208964:G1FZ6-1911-MONOMER | |
| BRENDA | 3.4.24.B16 | |
| EvolutionaryTrace | P14789 | |
| Proteomes | UP000002438 | |
| GO | GO:0005615 GO:0004175 GO:0046872 GO:0004222 GO:0009405 GO:0015628 GO:0043952 GO:0006508 | |
| InterPro | IPR011055 IPR000841 IPR016047 | |
| Pfam | PF01551 | |
| PRINTS | PR00933 | |
| SUPFAM | SSF51261 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0004175 |
peptidase inhibitor activity |
ECO:0000314 |
F |
The third group of columns in Fig. 4A (labeled lasA protease) Shows that the protease (peptidase) activity of P. aeruginosa lasA is inhibited by the introduction of A. alternata extract. |
complete | |||||
| GO:0009253 |
peptidoglycan catabolic process |
ECO:0000314 |
P |
The fourth group of columns in Fig. 4A (labeled lasA staphylolytic activity) Shows that the peptidoglycan degradation (staphylolytic) activity of P. aeruginosa lasA is inhibited by the introduction of A. alternata extract. |
complete | |||||
| GO:0061785 |
peptidoglycan endopeptidase activity |
ECO:0000314 |
F |
The fourth group of columns in Fig. 4A (labeled lasA staphylolytic activity) Shows that the peptidoglycan degradation (staphylolytic) activity of P. aeruginosa lasA is inhibited by the introduction of A. alternata extract. |
complete | |||||
|
involved_in |
GO:0043952 |
protein transport by the Sec complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0015628 |
protein secretion by the type II secretion system |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006508 |
proteolysis |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005615 |
extracellular space |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004175 |
endopeptidase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004222 |
metalloendopeptidase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006508 |
proteolysis |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006508 |
proteolysis |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008237 |
metallopeptidase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016787 |
hydrolase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008233 |
peptidase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009405 |
pathogenesis |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005576 |
extracellular region |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Rashmi, M et al. (2018) Anti-quorum sensing and antibiofilm potential of Alternaria alternata, a foliar endophyte of Carica papaya, evidenced by QS assays and in-silico analysis. Fungal Biol 122 998-1012 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Braun, P et al. (1998) Secretion of elastinolytic enzymes and their propeptides by Pseudomonas aeruginosa. J. Bacteriol. 180 3467-9 PubMed GONUTS page
- ↑ Olson, JC & Ohman, DE (1992) Efficient production and processing of elastase and LasA by Pseudomonas aeruginosa require zinc and calcium ions. J. Bacteriol. 174 4140-7 PubMed GONUTS page
- ↑ Passmore, IJ et al. (2015) Mep72, a metzincin protease that is preferentially secreted by biofilms of Pseudomonas aeruginosa. J. Bacteriol. 197 762-73 PubMed GONUTS page
b
e
m
p
- GO:0008233 ! peptidase activity
- GO:0009253 ! peptidoglycan catabolic process
- GO:0061785 ! peptidoglycan endopeptidase activity
- GO:0015628 ! protein secretion by the type II secretion system
- GO:0043952 ! protein transport by the Sec complex
- Proteobacteria
- GO:0006508 ! proteolysis
- Pseudomonadaceae
- Pseudomonadales
- Pseudomonas
- Pseudomonas aeruginosa
