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Category:GO:0043952 ! protein transport by the Sec complex
name: protein transport by the Sec complex
namespace: biological_process
def: "The process in which unfolded proteins are transported across the cytoplasmic membrane in Gram-positive and Gram-negative bacteria by the Sec complex, in a process involving proteolytic cleavage of an N-terminal signal peptide." [GOC:pamgo_curators]
comment: Note that this term represents an activity and not a cellular structure. Consider also annotating to the cellular structure term 'cell envelope Sec protein transport complex ; GO:0031522'. For proteins involved in bacterial type II secretion across the outer membrane, consider annotating to 'protein secretion by the type II secretion system ; GO:0015628'. For proteins involved in Sec-complex dependent translocation into the eukaryotic endoplasmic reticulum, consider annotating to 'SRP-dependent cotranslational protein targeting to membrane, translocation ; GO:0006616'. Note that this term is used for annotation of proteins that compose the transport complex but not the proteins being transported.
synonym: "protein secretion by the Sec complex" NARROW []
synonym: "protein translocation by the Sec complex" NARROW []
is_a: GO:0071806 ! protein transmembrane transport
AmiGO
<GOterm>GO:0043952</GOterm>
Gene Ontology Home
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Usage Notes
- This term applies to proteins in the Sec complex, NOT proteins that use the Sec secretion system for transport. See secA:Gene_Product(s)
References
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