GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
Category:GO:0003712 ! transcription coregulator activity
name: transcription coregulator activity
namespace: molecular_function
alt_id: GO:0001104
alt_id: GO:0016455
def: "A transcription regulator activity that modulates the transcription of specific gene sets via binding to a DNA-binding transcription factor at a specific genomic locus, either on its own or as part of a complex. Coregulators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second class remodels the conformation of chromatin in an ATP-dependent fashion. A third class modulates interactions of DNA-bound DNA-binding transcription factors with other transcription coregulators." [GOC:txnOH-2018, PMID:10213677, PMID:16858867, PMID:24203923, PMID:25957681, Wikipedia:Transcription_coregulator]
comment: Usage guidance: Most transcription coregulators do not bind DNA. Those that do usually bind DNA either in a non-specific or non-direct manner. If a protein binds DNA specifically, consider annotating to GO:0003700 DNA binding transcription factor activity.
subset: goslim_drosophila
synonym: "nuclear receptor coreceptor activity" NARROW []
synonym: "RNA polymerase II transcriptional cofactor activity" RELATED []
synonym: "transcription cofactor activity" EXACT []
synonym: "transcription coreceptor activity" EXACT []
synonym: "transcriptional co-regulator" EXACT []
is_a: GO:0030674 ! protein-macromolecule adaptor activity
is_a: GO:0140110 ! transcription regulator activity
AmiGO
<GOterm>GO:0003712</GOterm>
Gene Ontology Home
The contents of this box are automatically generated. You can help by adding information to the "Notes"
Usage Notes
References
See Help:References for how to manage references in GONUTS.
Child Terms
This category has the following 2 subcategories, out of 2 total.
Pages in category "GO:0003712 ! transcription coregulator activity"
The following 92 pages are in this category, out of 92 total.
Jump to pages starting with: A C D H M O P R W X
C
H
M
P
- PMID:10567590
- PMID:11333224
- PMID:11349124
- PMID:11416126
- PMID:11418595
- PMID:11509567
- PMID:11715043
- PMID:11854298
- PMID:11927560
- PMID:12021283
- PMID:12368867
- PMID:12835386
- PMID:14636573
- PMID:15297616
- PMID:15509804
- PMID:15710329
- PMID:17805299
- PMID:18451096
- PMID:18497331
- PMID:18515835
- PMID:18832382
- PMID:18945672
- PMID:19058135
- PMID:20570862
- PMID:20636338
- PMID:20843790
- PMID:21205034
- PMID:22396663
- PMID:24569844
- PMID:7776974
- PMID:7870181
- PMID:8524823
- PMID:8552098
- PMID:8684459