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MOUSE:SQSTM
Contents
Species (Taxon ID) | Mus musculus (Mouse). (10090) | |
Gene Name(s) | Sqstm1 (synonyms: A170, STAP) | |
Protein Name(s) | Sequestosome-1
STONE14 Ubiquitin-binding protein p62 | |
External Links | ||
UniProt | Q64337 | |
EMBL | U40930 U57413 AK028898 AL627187 AL627187 BC006019 | |
CCDS | CCDS24629.1 CCDS70176.1 | |
PIR | JC4978 | |
RefSeq | NP_001277698.1 NP_035148.1 | |
UniGene | Mm.40828 | |
PDB | 2RRU 2ZJD 3ADE 3B0F 3WDZ | |
PDBsum | 2RRU 2ZJD 3ADE 3B0F 3WDZ | |
ProteinModelPortal | Q64337 | |
SMR | Q64337 | |
BioGrid | 201982 | |
DIP | DIP-38490N | |
IntAct | Q64337 | |
MINT | MINT-1728610 | |
STRING | 10090.ENSMUSP00000099835 | |
PhosphoSite | Q64337 | |
MaxQB | Q64337 | |
PaxDb | Q64337 | |
PRIDE | Q64337 | |
Ensembl | ENSMUST00000015981 ENSMUST00000102774 | |
GeneID | 18412 | |
KEGG | mmu:18412 | |
UCSC | uc007irw.1 uc007irx.1 | |
CTD | 8878 | |
MGI | MGI:107931 | |
eggNOG | NOG278569 | |
GeneTree | ENSGT00390000002781 | |
HOGENOM | HOG000154407 | |
HOVERGEN | HBG052750 | |
InParanoid | Q64337 | |
KO | K14381 | |
OMA | SVCPNYD | |
OrthoDB | EOG74R1RT | |
PhylomeDB | Q64337 | |
TreeFam | TF328470 | |
Reactome | REACT_202271 REACT_214670 REACT_218887 REACT_224208 | |
ChiTaRS | Sqstm1 | |
EvolutionaryTrace | Q64337 | |
NextBio | 294036 | |
PRO | PR:Q64337 | |
Proteomes | UP000000589 | |
Bgee | Q64337 | |
CleanEx | MM_SQSTM1 | |
ExpressionAtlas | Q64337 | |
Genevestigator | Q64337 | |
GO | GO:0016235 GO:0005776 GO:0000932 GO:0031410 GO:0005783 GO:0070062 GO:0005770 GO:0005764 GO:0016605 GO:0000407 GO:0042802 GO:0070530 GO:0005080 GO:0042169 GO:0003712 GO:0043130 GO:0008270 GO:0006915 GO:0006914 GO:0030154 GO:0002376 GO:0016236 GO:0016239 GO:0001934 GO:0051291 GO:0043122 GO:1903506 | |
InterPro | IPR000270 IPR009060 IPR015940 IPR000433 | |
Pfam | PF00564 PF00569 | |
SMART | SM00666 SM00165 SM00291 | |
SUPFAM | SSF46934 | |
PROSITE | PS50030 PS01357 PS50135 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
GO:0044130 |
negative regulation of growth of symbiont in host |
ECO:0000315 |
P |
FIGURE 4, 5 |
complete | |||||
involved_in |
GO:0061912 |
selective autophagy |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:1905719 |
protein localization to perinuclear region of cytoplasm |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007032 |
endosome organization |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0035973 |
aggrephagy |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0044130 |
negative regulation of growth of symbiont in host |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:1903078 |
positive regulation of protein localization to plasma membrane |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
has_regulation_target:(UniProtKB:P23818) |
Seeded From UniProt |
complete | ||
involved_in |
GO:1900273 |
positive regulation of long-term synaptic potentiation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0035255 |
ionotropic glutamate receptor binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0070530 |
K63-linked polyubiquitin modification-dependent protein binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0043130 |
ubiquitin binding |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0043122 |
regulation of I-kappaB kinase/NF-kappaB signaling |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0042169 |
SH2 domain binding |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0016236 |
macroautophagy |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006914 |
autophagy |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005776 |
autophagosome |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0005080 |
protein kinase C binding |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0000932 |
P-body |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0070530 |
K63-linked polyubiquitin modification-dependent protein binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:107931 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0044753 |
amphisome |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000387090 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0035973 |
aggrephagy |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000387090 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0016235 |
aggresome |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:107931 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0007032 |
endosome organization |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000387090 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0007005 |
mitochondrion organization |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0003231 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005776 |
autophagosome |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0003231 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0005080 |
protein kinase C binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000387090 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0000423 |
mitophagy |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000387090 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:1905719 |
protein localization to perinuclear region of cytoplasm |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0098780 |
response to mitochondrial depolarisation |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0097413 |
Lewy body |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:69287 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0097225 |
sperm midpiece |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
exists_during:(GO:0009566) |
Seeded From UniProt |
complete | ||
enables |
GO:0070530 |
K63-linked polyubiquitin modification-dependent protein binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0061912 |
selective autophagy |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0061635 |
regulation of protein complex stability |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0051291 |
protein heterooligomerization |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:69287 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0044754 |
autolysosome |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0044754 |
autolysosome |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0044753 |
amphisome |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0043231 |
intracellular membrane-bounded organelle |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0043130 |
ubiquitin binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0043122 |
regulation of I-kappaB kinase/NF-kappaB signaling |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0042803 |
protein homodimerization activity |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:69287 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0042802 |
identical protein binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0042802 |
identical protein binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0042169 |
SH2 domain binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0035973 |
aggrephagy |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0031625 |
ubiquitin protein ligase binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0019901 |
protein kinase binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0019899 |
enzyme binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0016605 |
PML body |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0016236 |
macroautophagy |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0016235 |
aggresome |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0016234 |
inclusion body |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0007032 |
endosome organization |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0006914 |
autophagy |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005829 |
cytosol |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005776 |
autophagosome |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
|
Seeded From UniProt |
complete | ||
part_of |
GO:0005776 |
autophagosome |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005776 |
autophagosome |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005739 |
mitochondrion |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:69287 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0005080 |
protein kinase C binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0005080 |
protein kinase C binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:69287 |
F |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0001934 |
positive regulation of protein phosphorylation |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:69287 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0000932 |
P-body |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0000423 |
mitophagy |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0000407 |
phagophore assembly site |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
part_of:(CL:0000057) |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0000122 |
negative regulation of transcription by RNA polymerase II |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:3774352 |
P |
|
Seeded From UniProt |
complete | |
part_of |
GO:0097413 |
Lewy body |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O08623 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0051291 |
protein heterooligomerization |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O08623 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0042803 |
protein homodimerization activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O08623 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0005739 |
mitochondrion |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O08623 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0005080 |
protein kinase C binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O08623 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0002931 |
response to ischemia |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O08623 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0001934 |
positive regulation of protein phosphorylation |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O08623 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:1905719 |
protein localization to perinuclear region of cytoplasm |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q13501 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0098780 |
response to mitochondrial depolarisation |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q13501 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0070530 |
K63-linked polyubiquitin modification-dependent protein binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q13501 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0061912 |
selective autophagy |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q13501 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0061635 |
regulation of protein complex stability |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q13501 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0044754 |
autolysosome |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q13501 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0044753 |
amphisome |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q13501 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0043231 |
intracellular membrane-bounded organelle |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q13501 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0043130 |
ubiquitin binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q13501 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0043122 |
regulation of I-kappaB kinase/NF-kappaB signaling |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q13501 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0042802 |
identical protein binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q13501 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0042169 |
SH2 domain binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q13501 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0035973 |
aggrephagy |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q13501 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0031625 |
ubiquitin protein ligase binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q13501 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0019901 |
protein kinase binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q13501 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0019899 |
enzyme binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q13501 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0016605 |
PML body |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q13501 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0016236 |
macroautophagy |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q13501 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0016234 |
inclusion body |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q13501 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0007032 |
endosome organization |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q13501 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0006914 |
autophagy |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q13501 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005829 |
cytosol |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q13501 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005776 |
autophagosome |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q13501 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q13501 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0005080 |
protein kinase C binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q13501 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0000932 |
P-body |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q13501 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0000423 |
mitophagy |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q13501 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0008270 |
zinc ion binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0003712 |
transcription coregulator activity |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006915 |
apoptotic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006914 |
autophagy |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005768 |
endosome |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0030154 |
cell differentiation |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0031410 |
cytoplasmic vesicle |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005764 |
lysosome |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0002376 |
immune system process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005783 |
endoplasmic reticulum |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0030017 |
sarcomere |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005770 |
late endosome |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005776 |
autophagosome |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0016605 |
PML body |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005829 |
cytosol |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Abdulrahman, BA et al. (2013) Depletion of the ubiquitin-binding adaptor molecule SQSTM1/p62 from macrophages harboring cftr ΔF508 mutation improves the delivery of Burkholderia cenocepacia to the autophagic machinery. J. Biol. Chem. 288 2049-58 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Jiang, J et al. (2009) AMPA receptor trafficking and synaptic plasticity require SQSTM1/p62. Hippocampus 19 392-406 PubMed GONUTS page
- ↑ Geetha, T et al. (2005) TRAF6-mediated ubiquitination regulates nuclear translocation of NRIF, the p75 receptor interactor. EMBO J. 24 3859-68 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 4.4 4.5 4.6 4.7 4.8 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ Al Rawi, S et al. (2011) Postfertilization autophagy of sperm organelles prevents paternal mitochondrial DNA transmission. Science 334 1144-7 PubMed GONUTS page
- ↑ Varga, RE et al. (2015) In Vivo Evidence for Lysosome Depletion and Impaired Autophagic Clearance in Hereditary Spastic Paraplegia Type SPG11. PLoS Genet. 11 e1005454 PubMed GONUTS page
- ↑ 7.0 7.1 Itakura, E & Mizushima, N (2011) p62 Targeting to the autophagosome formation site requires self-oligomerization but not LC3 binding. J. Cell Biol. 192 17-27 PubMed GONUTS page
- ↑ Fusco, C et al. (2012) The E3-ubiquitin ligase TRIM50 interacts with HDAC6 and p62, and promotes the sequestration and clearance of ubiquitinated proteins into the aggresome. PLoS ONE 7 e40440 PubMed GONUTS page
- ↑ Sala, D et al. (2014) Autophagy-regulating TP53INP2 mediates muscle wasting and is repressed in diabetes. J. Clin. Invest. 124 1914-27 PubMed GONUTS page
- ↑ Dooley, HC et al. (2014) WIPI2 links LC3 conjugation with PI3P, autophagosome formation, and pathogen clearance by recruiting Atg12-5-16L1. Mol. Cell 55 238-52 PubMed GONUTS page
- ↑ Bonilla, DL et al. (2013) Autophagy regulates phagocytosis by modulating the expression of scavenger receptors. Immunity 39 537-47 PubMed GONUTS page
- ↑ Okazaki, M et al. (1999) Cloning, expression profile, and genomic organization of the mouse STAP/A170 gene. Genomics 60 87-95 PubMed GONUTS page
a
c
e
g
i
m
o
p
- GO:0000932 ! P-body
- GO:0000407 ! phagophore assembly site
- GO:0016605 ! PML body
- GO:0001934 ! positive regulation of protein phosphorylation
- GO:1903078 ! positive regulation of protein localization to plasma membrane
- GO:1900273 ! positive regulation of long-term synaptic potentiation
- GO:0051291 ! protein heterooligomerization
- GO:0042803 ! protein homodimerization activity
- GO:0019901 ! protein kinase binding
- GO:0005080 ! protein kinase C binding
- GO:1905719 ! protein localization to perinuclear region of cytoplasm
r