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HUMAN:DHX9
Contents
Species (Taxon ID) | Homo sapiens (Human). (9606) | |
Gene Name(s) | DHX9 (synonyms: DDX9, LKP, NDH2) | |
Protein Name(s) | ATP-dependent RNA helicase A
RHA DEAH box protein 9 Leukophysin LKP Nuclear DNA helicase II NDH II | |
External Links | ||
UniProt | Q08211 | |
EMBL | L13848 U03643 Y10658 AB451248 AB451372 AL355999 AL662837 AL662837 AL355999 CH471067 BC025245 BC058896 BC107881 BC137136 | |
CCDS | CCDS41444.1 | |
RefSeq | NP_001348.2 | |
UniGene | Hs.191518 | |
PDB | 3LLM 3VYX 3VYY | |
PDBsum | 3LLM 3VYX 3VYY | |
ProteinModelPortal | Q08211 | |
SMR | Q08211 | |
BioGrid | 108025 | |
DIP | DIP-31504N | |
IntAct | Q08211 | |
MINT | MINT-5000572 | |
STRING | 9606.ENSP00000356520 | |
iPTMnet | Q08211 | |
PhosphoSitePlus | Q08211 | |
SwissPalm | Q08211 | |
BioMuta | DHX9 | |
DMDM | 116241330 | |
SWISS-2DPAGE | Q08211 | |
EPD | Q08211 | |
MaxQB | Q08211 | |
PaxDb | Q08211 | |
PeptideAtlas | Q08211 | |
PRIDE | Q08211 | |
TopDownProteomics | Q08211-1 | |
Ensembl | ENST00000367549 | |
GeneID | 1660 | |
KEGG | hsa:1660 | |
UCSC | uc001gpr.4 | |
CTD | 1660 | |
DisGeNET | 1660 | |
GeneCards | DHX9 | |
H-InvDB | HIX0001404 HIX0149309 | |
HGNC | HGNC:2750 | |
HPA | CAB011819 HPA028050 HPA055684 | |
MIM | 603115 | |
neXtProt | NX_Q08211 | |
OpenTargets | ENSG00000135829 | |
PharmGKB | PA27232 | |
eggNOG | KOG0920 COG1643 | |
GeneTree | ENSGT00760000119189 | |
HOGENOM | HOG000247063 | |
HOVERGEN | HBG039429 | |
InParanoid | Q08211 | |
KO | K13184 | |
OMA | CSDHVAM | |
OrthoDB | EOG091G0PKT | |
PhylomeDB | Q08211 | |
TreeFam | TF313601 | |
BRENDA | 3.6.4.13 | |
Reactome | [www.reactome.org/content/detail/R-HSA-1810476 R-HSA-1810476] [www.reactome.org/content/detail/R-HSA-3134963 R-HSA-3134963] [www.reactome.org/content/detail/R-HSA-445989 R-HSA-445989] [www.reactome.org/content/detail/R-HSA-72163 R-HSA-72163] [www.reactome.org/content/detail/R-HSA-933542 R-HSA-933542] | |
ChiTaRS | DHX9 | |
GeneWiki | RNA_Helicase_A | |
GenomeRNAi | 1660 | |
PMAP-CutDB | Q08211 | |
PRO | PR:Q08211 | |
Proteomes | UP000005640 | |
Bgee | ENSG00000135829 | |
CleanEx | HS_DHX9 | |
Genevisible | Q08211 | |
GO | GO:0005813 GO:0070937 GO:0005737 GO:0036464 GO:0005829 GO:0030529 GO:0016020 GO:0097165 GO:0005730 GO:0005654 GO:0005634 GO:0005524 GO:0004003 GO:0004004 GO:0003677 GO:0003723 GO:0003724 GO:0001085 GO:0070934 GO:0000398 GO:0001649 GO:0032481 GO:1903608 GO:0048511 GO:0006396 | |
Gene3D | 3.30.160.20 3.40.50.300 | |
InterPro | IPR011545 IPR002464 IPR014720 IPR011709 IPR007502 IPR014001 IPR001650 IPR027417 | |
Pfam | PF00270 PF00035 PF04408 PF00271 PF07717 | |
SMART | SM00487 SM00358 SM00847 SM00490 | |
SUPFAM | SSF52540 | |
PROSITE | PS00690 PS50137 PS51192 PS51194 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
GO:0005654 |
nucleoplasm |
ECO:0000314 |
C |
Human DHX9. Figure 3, immunofluorescence spectroscopy shows localization to the nucleoplasm. |
complete | |||||
enables |
GO:0043140 |
ATP-dependent 3'-5' DNA helicase activity |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0017111 |
nucleoside-triphosphatase activity |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0016887 |
ATPase activity |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0004004 |
ATP-dependent RNA helicase activity |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0032508 |
DNA duplex unwinding |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:1990518 |
single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0045739 |
positive regulation of DNA repair |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:1990518 |
single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0031490 |
chromatin DNA binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0045142 |
triplex DNA binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005634 |
nucleus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005726 |
perichromatin fibrils |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0097165 |
nuclear stress granule |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0036464 |
cytoplasmic ribonucleoprotein granule |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0003697 |
single-stranded DNA binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0003727 |
single-stranded RNA binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0003725 |
double-stranded RNA binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0003729 |
mRNA binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0071356 |
cellular response to tumor necrosis factor |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0051092 |
positive regulation of NF-kappaB transcription factor activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:2000767 |
positive regulation of cytoplasmic translation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:1905538 |
polysome binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005844 |
polysome |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0000380 |
alternative mRNA splicing, via spliceosome |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:1990841 |
promoter-specific chromatin binding |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:1990904 |
ribonucleoprotein complex |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0003729 |
mRNA binding |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0004004 |
ATP-dependent RNA helicase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0016604 |
nuclear body |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005654 |
nucleoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0003725 |
double-stranded RNA binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0039695 |
DNA-templated viral transcription |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0050434 |
positive regulation of viral transcription |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0035613 |
RNA stem-loop binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:1902741 |
positive regulation of interferon-alpha secretion |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0071360 |
cellular response to exogenous dsRNA |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0060760 |
positive regulation of response to cytokine stimulus |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0035549 |
positive regulation of interferon-beta secretion |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:1904469 |
positive regulation of tumor necrosis factor secretion |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:2000778 |
positive regulation of interleukin-6 secretion |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0003697 |
single-stranded DNA binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0003725 |
double-stranded RNA binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0045944 |
positive regulation of transcription by RNA polymerase II |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:1905698 |
positive regulation of polysome binding |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005844 |
polysome |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:2000767 |
positive regulation of cytoplasmic translation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:1990904 |
ribonucleoprotein complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:1990904 |
ribonucleoprotein complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:1990825 |
sequence-specific mRNA binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0046833 |
positive regulation of RNA export from nucleus |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0045944 |
positive regulation of transcription by RNA polymerase II |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0000978 |
RNA polymerase II proximal promoter sequence-specific DNA binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:1990825 |
sequence-specific mRNA binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005634 |
nucleus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:1990904 |
ribonucleoprotein complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0003697 |
single-stranded DNA binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:1904469 |
positive regulation of tumor necrosis factor secretion |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:2000778 |
positive regulation of interleukin-6 secretion |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:1990904 |
ribonucleoprotein complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0004003 |
ATP-dependent DNA helicase activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0032508 |
DNA duplex unwinding |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:2000373 |
positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0003725 |
double-stranded RNA binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0003690 |
double-stranded DNA binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0045944 |
positive regulation of transcription by RNA polymerase II |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0016887 |
ATPase activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0005524 |
ATP binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0003712 |
transcription coregulator activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0000993 |
RNA polymerase II complex binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006357 |
regulation of transcription by RNA polymerase II |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0048146 |
positive regulation of fibroblast proliferation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0045740 |
positive regulation of DNA replication |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0003688 |
DNA replication origin binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0003677 |
DNA binding |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0010501 |
RNA secondary structure unwinding |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0003723 |
RNA binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0047429 |
nucleoside-triphosphate diphosphatase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0033681 |
ATP-dependent 3'-5' DNA/RNA helicase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0034459 |
ATP-dependent 3'-5' RNA helicase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0044806 |
G-quadruplex DNA unwinding |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0033681 |
ATP-dependent 3'-5' DNA/RNA helicase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0043140 |
ATP-dependent 3'-5' DNA helicase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0034459 |
ATP-dependent 3'-5' RNA helicase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0032508 |
DNA duplex unwinding |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:2000637 |
positive regulation of gene silencing by miRNA |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0030423 |
targeting of mRNA for destruction involved in RNA interference |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0070922 |
small RNA loading onto RISC |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0070578 |
RISC-loading complex |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:1905172 |
RISC complex binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0035068 |
micro-ribonucleoprotein complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0070269 |
pyroptosis |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0050729 |
positive regulation of inflammatory response |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0050691 |
regulation of defense response to virus by host |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0045089 |
positive regulation of innate immune response |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0032741 |
positive regulation of interleukin-18 production |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0003725 |
double-stranded RNA binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005634 |
nucleus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0015629 |
actin cytoskeleton |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0032991 |
protein-containing complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0003725 |
double-stranded RNA binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0003727 |
single-stranded RNA binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0003697 |
single-stranded DNA binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0003690 |
double-stranded DNA binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0010501 |
RNA secondary structure unwinding |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0032508 |
DNA duplex unwinding |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0045944 |
positive regulation of transcription by RNA polymerase II |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0003713 |
transcription coactivator activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0070063 |
RNA polymerase binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0001069 |
regulatory region RNA binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0050684 |
regulation of mRNA processing |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:2000765 |
regulation of cytoplasmic translation |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005634 |
nucleus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005634 |
nucleus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0061676 |
importin-alpha family protein binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005634 |
nucleus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0035613 |
RNA stem-loop binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:1990904 |
ribonucleoprotein complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:1905538 |
polysome binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0042788 |
polysomal ribosome |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:2000767 |
positive regulation of cytoplasmic translation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:1904973 |
positive regulation of viral translation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0035197 |
siRNA binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0035068 |
micro-ribonucleoprotein complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0097165 |
nuclear stress granule |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:1903608 |
protein localization to cytoplasmic stress granule |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005634 |
nucleus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005634 |
nucleus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
part_of:(CL:0000031) |
Seeded From UniProt |
complete | ||
part_of |
GO:0036464 |
cytoplasmic ribonucleoprotein granule |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
|
Seeded From UniProt |
complete | ||
part_of |
GO:0016020 |
membrane |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0016020 |
membrane |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
part_of:(CL:0000134)|part_of:(CL:0000062) |
Seeded From UniProt |
complete | ||
involved_in |
GO:0001649 |
osteoblast differentiation |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
P |
results_in_determination_of:(CL:0000134) |
Seeded From UniProt |
complete | ||
enables |
GO:0001085 |
RNA polymerase II transcription factor binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0070937 |
CRD-mediated mRNA stability complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0070934 |
CRD-mediated mRNA stabilization |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0003723 |
RNA binding |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0003723 |
RNA binding |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:1990904 |
ribonucleoprotein complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005813 |
centrosome |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005634 |
nucleus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:1990904 |
ribonucleoprotein complex |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001053532 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0050684 |
regulation of mRNA processing |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001053532 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0045944 |
positive regulation of transcription by RNA polymerase II |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0002774 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0043140 |
ATP-dependent 3'-5' DNA helicase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001053532 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0034459 |
ATP-dependent 3'-5' RNA helicase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001449167 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0005730 |
nucleolus |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:108177 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005634 |
nucleus |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0002774 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0004003 |
ATP-dependent DNA helicase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001053532 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0003723 |
RNA binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0002774 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:1990904 |
ribonucleoprotein complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0003676 |
nucleic acid binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0004386 |
helicase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0005524 |
ATP binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005634 |
nucleus |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0004004 |
ATP-dependent RNA helicase activity |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0004003 |
ATP-dependent DNA helicase activity |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0003724 |
RNA helicase activity |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005654 |
nucleoplasm |
Reactome:R-HSA-72124 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
|
C |
Seeded From UniProt |
complete | |
involved_in |
GO:0000398 |
mRNA splicing, via spliceosome |
Reactome:R-HSA-72163 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0032481 |
positive regulation of type I interferon production |
Reactome:R-HSA-1834949 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005829 |
cytosol |
Reactome:R-HSA-3134954 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
|
C |
Seeded From UniProt |
complete | |
part_of |
GO:0005856 |
cytoskeleton |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006417 |
regulation of translation |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0048511 |
rhythmic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0004386 |
helicase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0045087 |
innate immune response |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0000166 |
nucleotide binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0003677 |
DNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006260 |
DNA replication |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006954 |
inflammatory response |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0008380 |
RNA splicing |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006353 |
DNA-templated transcription, termination |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0016787 |
hydrolase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0031047 |
gene silencing by RNA |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0002376 |
immune system process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0005524 |
ATP binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0003723 |
RNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006397 |
mRNA processing |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0051028 |
mRNA transport |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005815 |
microtubule organizing center |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005654 |
nucleoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005730 |
nucleolus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 Capitanio, JS et al. (2017) Human Nup98 regulates the localization and activity of DExH/D-box helicase DHX9. Elife 6 PubMed GONUTS page
- ↑ Jain, A et al. (2010) Human DHX9 helicase unwinds triple-helical DNA structures. Biochemistry 49 6992-9 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 Jain, A et al. (2013) DHX9 helicase is involved in preventing genomic instability induced by alternatively structured DNA in human cells. Nucleic Acids Res. 41 10345-57 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 4.4 4.5 4.6 4.7 4.8 Zhang, S et al. (1999) Pre-mRNA and mRNA binding of human nuclear DNA helicase II (RNA helicase A). J. Cell. Sci. 112 ( Pt 7) 1055-64 PubMed GONUTS page
- ↑ 5.0 5.1 Tetsuka, T et al. (2004) RNA helicase A interacts with nuclear factor kappaB p65 and functions as a transcriptional coactivator. Eur. J. Biochem. 271 3741-51 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 Jin, J et al. (2011) Evidence that Lin28 stimulates translation by recruiting RNA helicase A to polysomes. Nucleic Acids Res. 39 3724-34 PubMed GONUTS page
- ↑ Boeras, I et al. (2016) DHX9/RHA Binding to the PBS-Segment of the Genomic RNA during HIV-1 Assembly Bolsters Virion Infectivity. J. Mol. Biol. 428 2418-2429 PubMed GONUTS page
- ↑ 8.0 8.1 8.2 Fujii, R et al. (2001) A Role of RNA Helicase A in cis-Acting Transactivation Response Element-mediated Transcriptional Regulation of Human Immunodeficiency Virus Type 1. J. Biol. Chem. 276 5445-51 PubMed GONUTS page
- ↑ 9.0 9.1 9.2 9.3 9.4 9.5 9.6 9.7 9.8 Zhang, Z et al. (2011) DHX9 pairs with IPS-1 to sense double-stranded RNA in myeloid dendritic cells. J. Immunol. 187 4501-8 PubMed GONUTS page
- ↑ 10.0 10.1 10.2 10.3 Manojlovic, Z & Stefanovic, B (2012) A novel role of RNA helicase A in regulation of translation of type I collagen mRNAs. RNA 18 321-34 PubMed GONUTS page
- ↑ 11.0 11.1 11.2 Yang, JP et al. (2001) Mapping the functional domains of HAP95, a protein that binds RNA helicase A and activates the constitutive transport element of type D retroviruses. J. Biol. Chem. 276 30694-700 PubMed GONUTS page
- ↑ 12.0 12.1 Myöhänen, S & Baylin, SB (2001) Sequence-specific DNA binding activity of RNA helicase A to the p16INK4a promoter. J. Biol. Chem. 276 1634-42 PubMed GONUTS page
- ↑ 13.0 13.1 13.2 Tang, H et al. (1997) A cellular cofactor for the constitutive transport element of type D retrovirus. Science 276 1412-5 PubMed GONUTS page
- ↑ Zhang, S et al. (2004) DNA-dependent protein kinase (DNA-PK) phosphorylates nuclear DNA helicase II/RNA helicase A and hnRNP proteins in an RNA-dependent manner. Nucleic Acids Res. 32 1-10 PubMed GONUTS page
- ↑ 15.0 15.1 15.2 15.3 Kim, T et al. (2010) Aspartate-glutamate-alanine-histidine box motif (DEAH)/RNA helicase A helicases sense microbial DNA in human plasmacytoid dendritic cells. Proc. Natl. Acad. Sci. U.S.A. 107 15181-6 PubMed GONUTS page
- ↑ 16.0 16.1 16.2 16.3 16.4 16.5 Zhou, K et al. (2003) RNA helicase A interacts with dsDNA and topoisomerase IIalpha. Nucleic Acids Res. 31 2253-60 PubMed GONUTS page
- ↑ 17.0 17.1 17.2 17.3 17.4 Aratani, S et al. (2001) Dual roles of RNA helicase A in CREB-dependent transcription. Mol. Cell. Biol. 21 4460-9 PubMed GONUTS page
- ↑ Anderson, SF et al. (1998) BRCA1 protein is linked to the RNA polymerase II holoenzyme complex via RNA helicase A. Nat. Genet. 19 254-6 PubMed GONUTS page
- ↑ 19.0 19.1 19.2 Lee, T et al. (2014) Suppression of the DHX9 helicase induces premature senescence in human diploid fibroblasts in a p53-dependent manner. J. Biol. Chem. 289 22798-814 PubMed GONUTS page
- ↑ 20.0 20.1 20.2 20.3 20.4 Lee, CG & Hurwitz, J (1992) A new RNA helicase isolated from HeLa cells that catalytically translocates in the 3' to 5' direction. J. Biol. Chem. 267 4398-407 PubMed GONUTS page
- ↑ 21.0 21.1 21.2 21.3 21.4 Chakraborty, P & Grosse, F (2011) Human DHX9 helicase preferentially unwinds RNA-containing displacement loops (R-loops) and G-quadruplexes. DNA Repair (Amst.) 10 654-65 PubMed GONUTS page
- ↑ 22.0 22.1 22.2 22.3 22.4 22.5 Robb, GB & Rana, TM (2007) RNA helicase A interacts with RISC in human cells and functions in RISC loading. Mol. Cell 26 523-37 PubMed GONUTS page
- ↑ Zhu, S et al. (2017) Nlrp9b inflammasome restricts rotavirus infection in intestinal epithelial cells. Nature 546 667-670 PubMed GONUTS page
- ↑ 24.0 24.1 24.2 Zhang, S et al. (2002) Nuclear DNA helicase II/RNA helicase A binds to filamentous actin. J. Biol. Chem. 277 843-53 PubMed GONUTS page
- ↑ 25.0 25.1 25.2 25.3 25.4 25.5 25.6 25.7 25.8 Zhang, S & Grosse, F (1997) Domain structure of human nuclear DNA helicase II (RNA helicase A). J. Biol. Chem. 272 11487-94 PubMed GONUTS page
- ↑ 26.0 26.1 26.2 Nakajima, T et al. (1997) RNA helicase A mediates association of CBP with RNA polymerase II. Cell 90 1107-12 PubMed GONUTS page
- ↑ 27.0 27.1 27.2 Aktaş, T et al. (2017) DHX9 suppresses RNA processing defects originating from the Alu invasion of the human genome. Nature 544 115-119 PubMed GONUTS page
- ↑ 28.0 28.1 Tang, H et al. (1999) The carboxyl terminus of RNA helicase A contains a bidirectional nuclear transport domain. Mol. Cell. Biol. 19 3540-50 PubMed GONUTS page
- ↑ 29.0 29.1 29.2 Aratani, S et al. (2006) The nuclear import of RNA helicase A is mediated by importin-alpha3. Biochem. Biophys. Res. Commun. 340 125-33 PubMed GONUTS page
- ↑ 30.0 30.1 30.2 30.3 30.4 30.5 30.6 30.7 Hartman, TR et al. (2006) RNA helicase A is necessary for translation of selected messenger RNAs. Nat. Struct. Mol. Biol. 13 509-16 PubMed GONUTS page
- ↑ 31.0 31.1 Fu, Q & Yuan, YA (2013) Structural insights into RISC assembly facilitated by dsRNA-binding domains of human RNA helicase A (DHX9). Nucleic Acids Res. 41 3457-70 PubMed GONUTS page
- ↑ 32.0 32.1 32.2 Jefferson, M et al. (2014) Host factors that interact with the pestivirus N-terminal protease, Npro, are components of the ribonucleoprotein complex. J. Virol. 88 10340-53 PubMed GONUTS page
- ↑ 33.0 33.1 Villacé, P et al. (2004) The composition of Staufen-containing RNA granules from human cells indicates their role in the regulated transport and translation of messenger RNAs. Nucleic Acids Res. 32 2411-20 PubMed GONUTS page
- ↑ Ghosh, D et al. (2010) Defining the membrane proteome of NK cells. J Mass Spectrom 45 1-25 PubMed GONUTS page
- ↑ 35.0 35.1 Foster, LJ et al. (2005) Differential expression profiling of membrane proteins by quantitative proteomics in a human mesenchymal stem cell line undergoing osteoblast differentiation. Stem Cells 23 1367-77 PubMed GONUTS page
- ↑ Amorim, BR et al. (2007) The transcriptional factor Osterix directly interacts with RNA helicase A. Biochem. Biophys. Res. Commun. 355 347-51 PubMed GONUTS page
- ↑ 37.0 37.1 Weidensdorfer, D et al. (2009) Control of c-myc mRNA stability by IGF2BP1-associated cytoplasmic RNPs. RNA 15 104-15 PubMed GONUTS page
- ↑ Castello, A et al. (2012) Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. Cell 149 1393-406 PubMed GONUTS page
- ↑ Baltz, AG et al. (2012) The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. Mol. Cell 46 674-90 PubMed GONUTS page
- ↑ Jønson, L et al. (2007) Molecular composition of IMP1 ribonucleoprotein granules. Mol. Cell Proteomics 6 798-811 PubMed GONUTS page
- ↑ 41.0 41.1 Zhang, S et al. (2007) Werner syndrome helicase (WRN), nuclear DNA helicase II (NDH II) and histone gammaH2AX are localized to the centrosome. Cell Biol. Int. 31 1109-21 PubMed GONUTS page
- ↑ 42.0 42.1 42.2 42.3 42.4 42.5 42.6 42.7 42.8 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ Maggi, LB Jr et al. (2008) Nucleophosmin serves as a rate-limiting nuclear export chaperone for the Mammalian ribosome. Mol. Cell. Biol. 28 7050-65 PubMed GONUTS page
- ↑ 44.0 44.1 Abdelhaleem, MM et al. (1996) Leukophysin: an RNA helicase A-related molecule identified in cytotoxic T cell granules and vesicles. J. Immunol. 156 2026-35 PubMed GONUTS page
a
- GO:0015629 ! actin cytoskeleton
- GO:0000380 ! alternative mRNA splicing, via spliceosome
- GO:0033681 ! ATP-dependent 3'-5' DNA/RNA helicase activity
- GO:0034459 ! ATP-dependent 3'-5' RNA helicase activity
- GO:0004004 ! ATP-dependent RNA helicase activity
- GO:0043140 ! ATP-dependent 3'-5' DNA helicase activity
- GO:0004003 ! ATP-dependent DNA helicase activity
- GO:0005524 ! ATP binding
- GO:0016887 ! ATP hydrolysis activity
c
- Catarrhini
- GO:0071360 ! cellular response to exogenous dsRNA
- GO:0071356 ! cellular response to tumor necrosis factor
- GO:0005813 ! centrosome
- Chordata
- GO:0031490 ! chromatin DNA binding
- Craniata
- GO:0070934 ! CRD-mediated mRNA stabilization
- GO:0070937 ! CRD-mediated mRNA stability complex
- GO:0005737 ! cytoplasm
- GO:0036464 ! cytoplasmic ribonucleoprotein granule
- GO:0005856 ! cytoskeleton
- GO:0005829 ! cytosol
d
- GO:0030425 ! dendrite
- GO:0006353 ! DNA-templated transcription termination
- GO:0039695 ! DNA-templated viral transcription
- GO:0003677 ! DNA binding
- GO:0032508 ! DNA duplex unwinding
- GO:0003688 ! DNA replication origin binding
- GO:0006260 ! DNA replication
- GO:0003725 ! double-stranded RNA binding
- GO:0003690 ! double-stranded DNA binding
h
i
m
n
o
p
- GO:0005726 ! perichromatin fibrils
- GO:2000767 ! positive regulation of cytoplasmic translation
- GO:0048146 ! positive regulation of fibroblast proliferation
- GO:0032481 ! positive regulation of type I interferon production
- GO:2000373 ! positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity
- GO:1902741 ! positive regulation of interferon-alpha secretion
- GO:0050434 ! positive regulation of viral transcription
- GO:0045944 ! positive regulation of transcription by RNA polymerase II
- GO:2000778 ! positive regulation of interleukin-6 secretion
- GO:1904469 ! positive regulation of tumor necrosis factor secretion
- GO:0035549 ! positive regulation of interferon-beta secretion
- GO:0046833 ! positive regulation of RNA export from nucleus
- GO:0045740 ! positive regulation of DNA replication
- GO:0051092 ! positive regulation of NF-kappaB transcription factor activity
- GO:0045739 ! positive regulation of DNA repair
- GO:2000637 ! positive regulation of miRNA-mediated gene silencing
- GO:0050729 ! positive regulation of inflammatory response
- GO:0045089 ! positive regulation of innate immune response
- GO:0032741 ! positive regulation of interleukin-18 production
- GO:0060760 ! positive regulation of response to cytokine stimulus
- GO:1904973 ! positive regulation of viral translation
- Primates
- GO:1990841 ! promoter-specific chromatin binding
- GO:0032991 ! protein-containing complex
- GO:1903608 ! protein localization to cytoplasmic stress granule
- GO:0070269 ! pyroptotic inflammatory response
r
- GO:0050691 ! regulation of defense response to virus by host
- GO:2000765 ! regulation of cytoplasmic translation
- GO:0006417 ! regulation of translation
- GO:0050684 ! regulation of mRNA processing
- GO:0006357 ! regulation of transcription by RNA polymerase II
- GO:0031047 ! regulatory ncRNA-mediated gene silencing
- GO:0001069 ! regulatory region RNA binding
- GO:0048511 ! rhythmic process
- GO:1990904 ! ribonucleoprotein complex
- GO:0017111 ! ribonucleoside triphosphate phosphatase activity
- GO:0070578 ! RISC-loading complex
- GO:0070922 ! RISC complex assembly
- GO:1905172 ! RISC complex binding
- GO:0003723 ! RNA binding
- GO:0003724 ! RNA helicase activity
- GO:0070063 ! RNA polymerase binding
- GO:0000978 ! RNA polymerase II cis-regulatory region sequence-specific DNA binding
- GO:0000993 ! RNA polymerase II complex binding
- GO:0001085 ! RNA polymerase II transcription factor binding
- GO:0010501 ! RNA secondary structure unwinding
- GO:0008380 ! RNA splicing
- GO:0035613 ! RNA stem-loop binding
s
t