CHICK:Q9PUA4

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	5-MCDG (ECO:0000313 with EMBL:AAF14308.1) (synonyms: TDG (ECO:0000313 with Ensembl:ENSGALP00000020740))
Protein Name(s)	G/T mismatch DNA glycosylase (ECO:0000313 with EMBL:AAF14308.1) Uncharacterized protein (ECO:0000313 with Ensembl:ENSGALP00000020740)
External Links
UniProt	Q9PUA4
EMBL	AADN03001375 AF202114
RefSeq	NP_990081.1
UniGene	Gga.3142
SMR	Q9PUA4
STRING	9031.ENSGALP00000020740
PaxDb	Q9PUA4
Ensembl	ENSGALT00000020769
GeneID	395510
KEGG	gga:395510
CTD	6996
eggNOG	COG3663
GeneTree	ENSGT00390000000987
HOGENOM	HOG000220820
HOVERGEN	HBG003685
KO	K03649
OMA	NGQWMTQ
OrthoDB	EOG790G1Z
PhylomeDB	Q9PUA4
TreeFam	TF328764
Reactome	REACT_115575 REACT_116144 REACT_220240 REACT_237284
NextBio	20815589
PRO	PR:Q9PUA4
Proteomes	UP000000539
GO	GO:0005654 GO:0005886 GO:0016605 GO:0030983 GO:0008263 GO:0001104 GO:0006284 GO:0006285 GO:0045008 GO:0080111 GO:0006281 GO:0009790 GO:0006298 GO:0035562 GO:0032091 GO:0000122
Gene3D	3.40.470.10
InterPro	IPR015637 IPR003310 IPR005122
PANTHER	PTHR12159
Pfam	PF03167
SMART	SM00986
SUPFAM	SSF52141
TIGRFAMs	TIGR00584

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
enables	GO:0008263	pyrimidine-specific mismatch base pair DNA N-glycosylase activity	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0026869 PANTHER:PTN000255408 UniProtKB:Q13569	F	Seeded From UniProt	complete
involved_in	GO:0006285	base-excision repair, AP site formation	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000255408 UniProtKB:Q13569	P	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:108247 PANTHER:PTN000952417 RGD:620959 UniProtKB:Q13569	C	Seeded From UniProt	complete
enables	GO:0004844	uracil DNA N-glycosylase activity	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000255408 PomBase:SPCC965.05c UniProtKB:Q13569	F	Seeded From UniProt	complete
involved_in	GO:0080111	DNA demethylation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P56581 ensembl:ENSMUSP00000121000	P	Seeded From UniProt	complete
involved_in	GO:0045995	regulation of embryonic development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P56581 ensembl:ENSMUSP00000121000	P	Seeded From UniProt	complete
involved_in	GO:0040029	regulation of gene expression, epigenetic	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P56581 ensembl:ENSMUSP00000121000	P	Seeded From UniProt	complete
involved_in	GO:0035562	negative regulation of chromatin binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P56581 ensembl:ENSMUSP00000121000	P	Seeded From UniProt	complete
enables	GO:0032183	SUMO binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P56581 ensembl:ENSMUSP00000121000	F	Seeded From UniProt	complete
involved_in	GO:0032091	negative regulation of protein binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P56581 ensembl:ENSMUSP00000121000	P	Seeded From UniProt	complete
enables	GO:0019104	DNA N-glycosylase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P56581 ensembl:ENSMUSP00000121000	F	Seeded From UniProt	complete
part_of	GO:0016605	PML body	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P56581 ensembl:ENSMUSP00000121000	C	Seeded From UniProt	complete
involved_in	GO:0006284	base-excision repair	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P56581 ensembl:ENSMUSP00000121000	P	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P56581 ensembl:ENSMUSP00000121000	C	Seeded From UniProt	complete
enables	GO:0005080	protein kinase C binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P56581 ensembl:ENSMUSP00000121000	F	Seeded From UniProt	complete
enables	GO:0003712	transcription coregulator activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P56581 ensembl:ENSMUSP00000121000	F	Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P56581 ensembl:ENSMUSP00000121000	F	Seeded From UniProt	complete
involved_in	GO:0000122	negative regulation of transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P56581 ensembl:ENSMUSP00000121000	P	Seeded From UniProt	complete
involved_in	GO:1902544	regulation of DNA N-glycosylase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13569 ensembl:ENSP00000376611	P	Seeded From UniProt	complete
enables	GO:0043739	G/U mismatch-specific uracil-DNA glycosylase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13569 ensembl:ENSP00000376611	F	Seeded From UniProt	complete
enables	GO:0043621	protein self-association	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13569 ensembl:ENSP00000376611	F	Seeded From UniProt	complete
enables	GO:0042803	protein homodimerization activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13569 ensembl:ENSP00000376611	F	Seeded From UniProt	complete
enables	GO:0032183	SUMO binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13569 ensembl:ENSP00000376611	F	Seeded From UniProt	complete
enables	GO:0031404	chloride ion binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13569 ensembl:ENSP00000376611	F	Seeded From UniProt	complete
enables	GO:0031402	sodium ion binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13569 ensembl:ENSP00000376611	F	Seeded From UniProt	complete
enables	GO:0030983	mismatched DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13569 ensembl:ENSP00000376611	F	Seeded From UniProt	complete
enables	GO:0019104	DNA N-glycosylase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13569 ensembl:ENSP00000376611	F	Seeded From UniProt	complete
enables	GO:0008263	pyrimidine-specific mismatch base pair DNA N-glycosylase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13569 ensembl:ENSP00000376611	F	Seeded From UniProt	complete
involved_in	GO:0006298	mismatch repair	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13569 ensembl:ENSP00000376611	P	Seeded From UniProt	complete
involved_in	GO:0006285	base-excision repair, AP site formation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13569 ensembl:ENSP00000376611	P	Seeded From UniProt	complete
involved_in	GO:0006284	base-excision repair	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13569 ensembl:ENSP00000376611	P	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13569 ensembl:ENSP00000376611	C	Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13569 ensembl:ENSP00000376611	C	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13569 ensembl:ENSP00000376611	C	Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13569 ensembl:ENSP00000376611	F	Seeded From UniProt	complete
enables	GO:0004844	uracil DNA N-glycosylase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13569 ensembl:ENSP00000376611	F	Seeded From UniProt	complete
enables	GO:0003690	double-stranded DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13569 ensembl:ENSP00000376611	F	Seeded From UniProt	complete
enables	GO:0000287	magnesium ion binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q13569 ensembl:ENSP00000376611	F	Seeded From UniProt	complete
involved_in	GO:0006281	DNA repair	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR003310 InterPro:IPR015637	P	Seeded From UniProt	complete
enables	GO:0019104	DNA N-glycosylase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR003310 InterPro:IPR015637	F	Seeded From UniProt	complete
involved_in	GO:0045008	depyrimidination	Reactome:R-GGA-353446	ECO:0000304	author statement supported by traceable reference used in manual assertion		P	Seeded From UniProt	complete
enables	GO:0019104	DNA N-glycosylase activity	Reactome:R-GGA-353481 Reactome:R-GGA-353444 Reactome:R-GGA-353426 Reactome:R-GGA-353277	ECO:0000304	author statement supported by traceable reference used in manual assertion		F	Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	Reactome:R-GGA-353481 Reactome:R-GGA-353444 Reactome:R-GGA-353426 Reactome:R-GGA-353277	ECO:0000304	author statement supported by traceable reference used in manual assertion		C	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:21873635-1] 1.0 ^1.1 ^1.2 ^1.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

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CHICK:Q9PUA4

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