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Category:GO:0070059 ! intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress

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DAG for GO:0070059id: GO:0070059

name: intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
namespace: biological_process
def: "A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to a stimulus indicating endoplasmic reticulum (ER) stress, and ends when the execution phase of apoptosis is triggered. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen." [GOC:mah, GOC:mtg_apoptosis, PMID:18701708]
synonym: "apoptosis in response to endoplasmic reticulum stress" BROAD []
synonym: "apoptosis in response to ER stress" EXACT []
synonym: "apoptosis triggered by ER stress" EXACT []
synonym: "endoplasmic reticulum stress-induced apoptosis" EXACT []
synonym: "ER stress-induced apoptosis" EXACT []
synonym: "intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress" EXACT []
is_a: GO:0034976 ! response to endoplasmic reticulum stress
is_a: GO:0097193 ! intrinsic apoptotic signaling pathway

AmiGO <GOterm>GO:0070059</GOterm>
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