HUMAN:ERO1A

Species (Taxon ID)	Homo sapiens (Human). (9606)
Gene Name(s)	ERO1L
Protein Name(s)	ERO1-like protein alpha ERO1-L ERO1-L-alpha Endoplasmic oxidoreductin-1-like protein Oxidoreductin-1-L-alpha
External Links
UniProt	Q96HE7
EMBL	AF081886 AF123887 AY358463 AK292839 AL133453 BC008674 BC012941
CCDS	CCDS9709.1
RefSeq	NP_055399.1
UniGene	Hs.592304
PDB	3AHQ 3AHR
PDBsum	3AHQ 3AHR
ProteinModelPortal	Q96HE7
SMR	Q96HE7
BioGrid	119025
IntAct	Q96HE7
MINT	MINT-144080
STRING	9606.ENSP00000379042
BindingDB	Q96HE7
ChEMBL	CHEMBL1671609
PhosphoSite	Q96HE7
DMDM	50400608
MaxQB	Q96HE7
PaxDb	Q96HE7
PeptideAtlas	Q96HE7
PRIDE	Q96HE7
DNASU	30001
Ensembl	ENST00000395686
GeneID	30001
KEGG	hsa:30001
UCSC	uc001wzv.3
CTD	30001
GeneCards	GC14M053106
HGNC	HGNC:13280
HPA	CAB034294 HPA026653 HPA030053
MIM	615435
neXtProt	NX_Q96HE7
PharmGKB	PA27862
eggNOG	COG5061
GeneTree	ENSGT00390000007753
HOGENOM	HOG000012778
HOVERGEN	HBG051507
InParanoid	Q96HE7
KO	K10950
OMA	CHSDEVP
OrthoDB	EOG7PP579
PhylomeDB	Q96HE7
TreeFam	TF314471
Reactome	REACT_15550 REACT_172715
ChiTaRS	ERO1L
EvolutionaryTrace	Q96HE7
GeneWiki	ERO1L
GenomeRNAi	30001
NextBio	52816
PRO	PR:Q96HE7
Proteomes	UP000005640
Bgee	Q96HE7
CleanEx	HS_ERO1L
ExpressionAtlas	Q96HE7
Genevestigator	Q96HE7
GO	GO:0005783 GO:0005788 GO:0005789 GO:0043231 GO:0016020 GO:0016491 GO:0016671 GO:0003756 GO:0015035 GO:0019471 GO:0050873 GO:0045454 GO:0044267 GO:0006464 GO:0051085 GO:0030968 GO:0030198 GO:0070059 GO:0006457 GO:0022417 GO:0051209 GO:0034976 GO:0009266
InterPro	IPR007266
PANTHER	PTHR12613
Pfam	PF04137
PIRSF	PIRSF017205

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
part_of	GO:0016020	membrane	PMID:19946888	ECO:0007005	high throughput direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q8R180	P		Seeded From UniProt	complete
involved_in	GO:0051209	release of sequestered calcium ion into cytosol	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q8R180	P		Seeded From UniProt	complete
involved_in	GO:0051085	chaperone cofactor-dependent protein refolding	PMID:11707400	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0034976	response to endoplasmic reticulum stress	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q8R180	P		Seeded From UniProt	complete
enables	GO:0016491	oxidoreductase activity	PMID:11707400	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
part_of	GO:0005783	endoplasmic reticulum	PMID:10671517	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0034975	protein folding in endoplasmic reticulum		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0261274 PANTHER:PTN000289179 SGD:S000004599 WB:WBGene00001334	P		Seeded From UniProt	complete
enables	GO:0015035	protein disulfide oxidoreductase activity		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1354385 MGI:MGI:1914725 PANTHER:PTN000289179 PomBase:SPCC1450.14c	F		Seeded From UniProt	complete
part_of	GO:0005789	endoplasmic reticulum membrane		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000289179 PomBase:SPBC4F6.16c PomBase:SPCC1450.14c UniProtKB:Q6AVU2	C		Seeded From UniProt	complete
enables	GO:0003756	protein disulfide isomerase activity		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0261274 PANTHER:PTN000289179 SGD:S000004599	F		Seeded From UniProt	complete
involved_in	GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8R180 ensembl:ENSMUSP00000022378	P		Seeded From UniProt	complete
involved_in	GO:0055114	oxidation-reduction process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8R180 ensembl:ENSMUSP00000022378	P		Seeded From UniProt	complete
involved_in	GO:0051209	release of sequestered calcium ion into cytosol	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8R180 ensembl:ENSMUSP00000022378	P		Seeded From UniProt	complete
involved_in	GO:0050873	brown fat cell differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8R180 ensembl:ENSMUSP00000022378	P		Seeded From UniProt	complete
involved_in	GO:0045454	cell redox homeostasis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8R180 ensembl:ENSMUSP00000022378	P		Seeded From UniProt	complete
involved_in	GO:0034976	response to endoplasmic reticulum stress	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8R180 ensembl:ENSMUSP00000022378	P		Seeded From UniProt	complete
involved_in	GO:0030968	endoplasmic reticulum unfolded protein response	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8R180 ensembl:ENSMUSP00000022378	P		Seeded From UniProt	complete
involved_in	GO:0030198	extracellular matrix organization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8R180 ensembl:ENSMUSP00000022378	P		Seeded From UniProt	complete
involved_in	GO:0022417	protein maturation by protein folding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8R180 ensembl:ENSMUSP00000022378	P		Seeded From UniProt	complete
involved_in	GO:0019471	4-hydroxyproline metabolic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8R180 ensembl:ENSMUSP00000022378	P		Seeded From UniProt	complete
enables	GO:0016491	oxidoreductase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8R180 ensembl:ENSMUSP00000022378	F		Seeded From UniProt	complete
enables	GO:0015035	protein disulfide oxidoreductase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8R180 ensembl:ENSMUSP00000022378	F		Seeded From UniProt	complete
involved_in	GO:0006457	protein folding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8R180 ensembl:ENSMUSP00000022378	P		Seeded From UniProt	complete
involved_in	GO:0071456	cellular response to hypoxia	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8R4A1 ensembl:ENSRNOP00000009404	P		Seeded From UniProt	complete
part_of	GO:0030425	dendrite	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8R4A1 ensembl:ENSRNOP00000009404	C		Seeded From UniProt	complete
involved_in	GO:0010260	animal organ senescence	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8R4A1 ensembl:ENSRNOP00000009404	P		Seeded From UniProt	complete
enables	GO:0003756	protein disulfide isomerase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR007266 InterPro:IPR037192	F		Seeded From UniProt	complete
part_of	GO:0005783	endoplasmic reticulum	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR007266 InterPro:IPR037192	C		Seeded From UniProt	complete
enables	GO:0016671	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR007266 InterPro:IPR037192	F		Seeded From UniProt	complete
involved_in	GO:0055114	oxidation-reduction process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR007266 InterPro:IPR037192	P		Seeded From UniProt	complete
part_of	GO:0043231	intracellular membrane-bounded organelle	PMID:10671517	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0016020	membrane	PMID:10671517	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0009266	response to temperature stimulus	PMID:10671517	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006464	cellular protein modification process	PMID:10671517	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006457	protein folding	PMID:10671517	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005783	endoplasmic reticulum	PMID:10671517	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0034599	cellular response to oxidative stress	Reactome:R-HSA-3299685	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005788	endoplasmic reticulum lumen	Reactome:R-HSA-3341296 Reactome:R-HSA-264997	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C		Seeded From UniProt	complete
involved_in	GO:0055114	oxidation-reduction process	GO_REF:0000037 GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0249 UniProtKB-KW:KW-0560	P		Seeded From UniProt	complete
involved_in	GO:0006915	apoptotic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0053	P		Seeded From UniProt	complete
part_of	GO:0005783	endoplasmic reticulum	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0256	C		Seeded From UniProt	complete
enables	GO:0016491	oxidoreductase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0560	F		Seeded From UniProt	complete
part_of	GO:0005789	endoplasmic reticulum membrane	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0097	C		Seeded From UniProt	complete
edit table

References

See Help:References for how to manage references in GONUTS.