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Category:GO:0051213 ! dioxygenase activity
name: dioxygenase activity
namespace: molecular_function
def: "Catalysis of an oxidation-reduction (redox) reaction in which both atoms of oxygen from one molecule of O2 are incorporated into the (reduced) product(s) of the reaction. The two atoms of oxygen may be distributed between two different products." [DOI:10.1016/S0040-4020(03)00944-X, GOC:bf]
subset: goslim_pir
is_a: GO:0016491 ! oxidoreductase activity
AmiGO
<GOterm>GO:0051213</GOterm>
Gene Ontology Home
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Usage Notes
Oxygenases are enzymes that incorporate oxygen atoms from O2 into the product(s). Monooxygenases catalyze the incorporation of one oxygen atom from O2 into the product; the other oxygen atom is reduced to H2O.[1] Dioxygenases incorporate both atoms of oxygen from a molecule of O2 into the product (or products) of the reaction[1]. Note that one of the molecules incorporating an oxygen may not be obvious from simplified descriptions of the reaction mechanism. For example, there are many ketoglutarate-dependent dioxygenases that convert ketoglutarate to succinate while transferring an oxygen to a more specialized substrate. In reading papers about such enzymes, the formation of succinate can be missed easily.
References
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Child Terms
This category has the following 6 subcategories, out of 6 total.
