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CAUCN:ALKB

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Species (Taxon ID) Caulobacter crescentus (strain NA1000 / CB15N). (565050)
Gene Name(s) alkB
Protein Name(s) Alpha-ketoglutarate-dependent dioxygenase AlkB homolog

DNA oxidative demethylase AlkB

External Links
UniProt B8GWW6
EMBL U73681
CP001340
RefSeq YP_002515384.1
ProteinModelPortal B8GWW6
SMR B8GWW6
EnsemblBacteria ACL93476
GeneID 7333150
KEGG ccs:CCNA_00009
PATRIC 21304583
HOGENOM HOG000122276
KO K03919
OMA NSCLFRV
OrthoDB POG091H0F7C
Proteomes UP000001364
GO GO:0103053
GO:0046872
GO:0006281
Gene3D 2.60.120.590
InterPro IPR004574
IPR027450
IPR005123
PANTHER PTHR16557
Pfam PF13532
PROSITE PS51471

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0006307

DNA dealkylation involved in DNA repair

PMID:9150207[1]

ECO:0000315

P

Figure 4 shows that the survival of Caulobacter crescentus with a deletion in the AlkB gene is compensated 100fold under .01% methyl methane sulfonate conditions. This shows that AlkB plays a role in the cells defense against alkylation.

complete
CACAO 12728

enables

GO:0016491

oxidoreductase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005123

F

Seeded From UniProt

complete

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004574
InterPro:IPR005123

P

Seeded From UniProt

complete

enables

GO:0103053

1-ethyladenine demethylase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:1.14.11.33

F

Seeded From UniProt

complete

involved_in

GO:0006974

cellular response to DNA damage stimulus

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0227

P

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

involved_in

GO:0006281

DNA repair

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0234

P

Seeded From UniProt

complete

enables

GO:0051213

dioxygenase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0223

F

Seeded From UniProt

complete

enables

GO:0016491

oxidoreductase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0560

F

Seeded From UniProt

complete

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0560

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Colombi, D & Gomes, SL (1997) An alkB gene homolog is differentially transcribed during the Caulobacter crescentus cell cycle. J. Bacteriol. 179 3139-45 PubMed GONUTS page