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DROME:MTND
Contents
| Species (Taxon ID) | Drosophila melanogaster (Fruit fly). (7227) | |
| Gene Name(s) | No Information Provided. | |
| Protein Name(s) | 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase (ECO:0000255 with HAMAP-Rule:MF_03154)
Acireductone dioxygenase (Fe(2+)-requiring) (ECO:0000255 with HAMAP-Rule:MF_03154) ARD (ECO:0000255 with HAMAP-Rule:MF_03154) Fe-ARD (ECO:0000255 with HAMAP-Rule:MF_03154) | |
| External Links | ||
| UniProt | Q6AWN0 | |
| EMBL | AE014296 BT015218 | |
| RefSeq | NP_001097577.1 | |
| UniGene | Dm.15417 | |
| ProteinModelPortal | Q6AWN0 | |
| SMR | Q6AWN0 | |
| BioGrid | 77443 | |
| IntAct | Q6AWN0 | |
| MINT | MINT-832699 | |
| STRING | 7227.FBpp0112333 | |
| PaxDb | Q6AWN0 | |
| EnsemblMetazoa | FBtr0113421 | |
| GeneID | 326189 | |
| KEGG | dme:Dmel_CG32068 | |
| UCSC | CG32068-RB | |
| FlyBase | FBgn0052068 | |
| eggNOG | COG1791 | |
| GeneTree | ENSGT00390000008195 | |
| InParanoid | Q6AWN0 | |
| KO | K08967 | |
| OMA | VWIRIWV | |
| OrthoDB | EOG73FQP0 | |
| PhylomeDB | Q6AWN0 | |
| Reactome | REACT_180809 | |
| UniPathway | UPA00904 | |
| GenomeRNAi | 326189 | |
| NextBio | 847541 | |
| PRO | PR:Q6AWN0 | |
| Proteomes | UP000000803 | |
| Bgee | Q6AWN0 | |
| ExpressionAtlas | Q6AWN0 | |
| GO | GO:0005737 GO:0005634 GO:0005886 GO:0010309 GO:0005506 GO:0016491 GO:0019509 | |
| Gene3D | 2.60.120.10 | |
| HAMAP | MF_03154 | |
| InterPro | IPR004313 IPR027496 IPR014710 IPR011051 | |
| PANTHER | PTHR23418 | |
| Pfam | PF03079 | |
| SUPFAM | SSF51182 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0009086 |
methionine biosynthetic process |
ECO:0000315 |
P |
Figure 5-comparing metabolites produced in wildtype to metabolites produced in Dadi1 mutant. |
complete | |||||
| GO:2000243 |
positive regulation of reproductive process |
ECO:0000315 |
P |
Figure 2a: when flies receive poor nutrition wildtype expressing Dadi1 are more fecund, Figure 2b/c: when Dadi1 introduced to flies not expressing Dadi1, fertility increases |
complete | |||||
|
involved_in |
GO:2000243 |
positive regulation of reproductive process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009086 |
methionine biosynthetic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0019509 |
L-methionine salvage from methylthioadenosine |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016491 |
oxidoreductase activity |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0010309 |
acireductone dioxygenase [iron(II)-requiring] activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000602608 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006555 |
methionine metabolic process |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0052068 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006555 |
methionine metabolic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0010309 |
acireductone dioxygenase [iron(II)-requiring] activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016491 |
oxidoreductase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0019509 |
L-methionine salvage from methylthioadenosine |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0010309 |
acireductone dioxygenase [iron(II)-requiring] activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000336851 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005506 |
iron ion binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000336851 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000336851 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0010309 |
acireductone dioxygenase [iron(II)-requiring] activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000336851 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0019509 |
L-methionine salvage from methylthioadenosine |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000336851 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0051213 |
dioxygenase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0008652 |
cellular amino acid biosynthetic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009086 |
methionine biosynthetic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016491 |
oxidoreductase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0019509 |
L-methionine salvage from methylthioadenosine |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniPathway:UPA00904 |
P |
Seeded From UniProt |
complete | ||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 Chou, HY et al. (2014) ADI1, a methionine salvage pathway enzyme, is required for Drosophila fecundity. J. Biomed. Sci. 21 64 PubMed GONUTS page
- ↑ 2.0 2.1 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
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