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CHICK:PGH2
Contents
Species (Taxon ID) | Gallus gallus (Chicken). (9031) | |
Gene Name(s) | PTGS2 (synonyms: CEF-147) | |
Protein Name(s) | Prostaglandin G/H synthase 2
Cyclooxygenase-2 COX-2 Mitogen-inducible PGHS PHS II Prostaglandin H2 synthase 2 PGH synthase 2 PGHS-2 Prostaglandin-endoperoxide synthase 2 | |
External Links | ||
UniProt | P27607 | |
EMBL | M64990 | |
PIR | A38630 | |
RefSeq | NP_001161190.1 NP_001161191.1 | |
UniGene | Gga.4401 | |
ProteinModelPortal | P27607 | |
SMR | P27607 | |
STRING | 9031.ENSGALP00000008111 | |
PeroxiBase | 4107 | |
PaxDb | P27607 | |
GeneID | 396451 | |
KEGG | gga:396451 | |
CTD | 5743 | |
eggNOG | NOG39991 | |
HOGENOM | HOG000013149 | |
HOVERGEN | HBG000366 | |
InParanoid | P27607 | |
KO | K11987 | |
OrthoDB | EOG7RFTHC | |
PhylomeDB | P27607 | |
TreeFam | TF329675 | |
Reactome | REACT_194363 REACT_198071 REACT_245396 | |
UniPathway | UPA00662 | |
NextBio | 20816492 | |
PRO | PR:P27607 | |
Proteomes | UP000000539 | |
ExpressionAtlas | P27607 | |
GO | GO:0005737 GO:0005789 GO:0005634 GO:0051213 GO:0020037 GO:0046872 GO:0004601 GO:0004666 GO:0019371 GO:0006954 GO:0001516 GO:0008217 GO:0006979 | |
Gene3D | 1.10.640.10 | |
InterPro | IPR029576 IPR000742 IPR010255 IPR019791 | |
PANTHER | PTHR11903:SF8 | |
Pfam | PF03098 | |
PRINTS | PR00457 | |
SUPFAM | SSF48113 | |
PROSITE | PS50026 PS50292 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
enables |
GO:0020037 |
heme binding |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0019371 |
cyclooxygenase pathway |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0008217 |
regulation of blood pressure |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0004666 |
prostaglandin-endoperoxide synthase activity |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0001516 |
prostaglandin biosynthetic process |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0098869 |
cellular oxidant detoxification |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0004601 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0098869 |
cellular oxidant detoxification |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0004601 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0071456 |
cellular response to hypoxia |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P35354 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0043005 |
neuron projection |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P35354 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0019899 |
enzyme binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P35354 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0019371 |
cyclooxygenase pathway |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P35354 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005783 |
endoplasmic reticulum |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P35354 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P35354 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0004666 |
prostaglandin-endoperoxide synthase activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P35354 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:1902219 |
negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q05769 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0090336 |
positive regulation of brown fat cell differentiation |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q05769 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0071498 |
cellular response to fluid shear stress |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q05769 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0071471 |
cellular response to non-ionic osmotic stress |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q05769 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0043154 |
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q05769 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0043066 |
negative regulation of apoptotic process |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q05769 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0043005 |
neuron projection |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q05769 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0042803 |
protein homodimerization activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q05769 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0042127 |
regulation of cell population proliferation |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q05769 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0033138 |
positive regulation of peptidyl-serine phosphorylation |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q05769 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0031622 |
positive regulation of fever generation |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q05769 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0031394 |
positive regulation of prostaglandin biosynthetic process |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q05769 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0020037 |
heme binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q05769 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0019371 |
cyclooxygenase pathway |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q05769 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0008217 |
regulation of blood pressure |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q05769 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q05769 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0004666 |
prostaglandin-endoperoxide synthase activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q05769 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0001516 |
prostaglandin biosynthetic process |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q05769 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0001516 |
prostaglandin biosynthetic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0004601 |
peroxidase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0004666 |
prostaglandin-endoperoxide synthase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006954 |
inflammatory response |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006979 |
response to oxidative stress |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0008217 |
regulation of blood pressure |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0019371 |
cyclooxygenase pathway |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0020037 |
heme binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0004666 |
prostaglandin-endoperoxide synthase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0004601 |
peroxidase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006633 |
fatty acid biosynthetic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006693 |
prostaglandin metabolic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006631 |
fatty acid metabolic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0043231 |
intracellular membrane-bounded organelle |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005783 |
endoplasmic reticulum |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0051213 |
dioxygenase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0001516 |
prostaglandin biosynthetic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0643 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0016491 |
oxidoreductase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006629 |
lipid metabolic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0031090 |
organelle membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005789 |
endoplasmic reticulum membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
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- GO:0004601 ! peroxidase activity
- Phasianidae
- Phasianinae
- GO:0031622 ! positive regulation of fever generation
- GO:0090336 ! positive regulation of brown fat cell differentiation
- GO:0031394 ! positive regulation of prostaglandin biosynthetic process
- GO:0033138 ! positive regulation of peptidyl-serine phosphorylation
- GO:0004666 ! prostaglandin-endoperoxide synthase activity
- GO:0001516 ! prostaglandin biosynthetic process
- GO:0006693 ! prostaglandin metabolic process
- GO:0042803 ! protein homodimerization activity
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