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HUMAN:ALKB4
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | ALKBH4 (synonyms: ABH4) | |
| Protein Name(s) | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4
Alkylated DNA repair protein alkB homolog 4 | |
| External Links | ||
| UniProt | Q9NXW9 | |
| EMBL | AK000020 AK026097 AK222689 AC093668 BC002820 BC017096 | |
| CCDS | CCDS5723.1 | |
| RefSeq | NP_060091.1 XP_005250521.1 | |
| UniGene | Hs.658598 | |
| ProteinModelPortal | Q9NXW9 | |
| BioGrid | 120148 | |
| IntAct | Q9NXW9 | |
| STRING | 9606.ENSP00000292566 | |
| DMDM | 74734701 | |
| MaxQB | Q9NXW9 | |
| PaxDb | Q9NXW9 | |
| PRIDE | Q9NXW9 | |
| DNASU | 54784 | |
| Ensembl | ENST00000292566 ENST00000490528 | |
| GeneID | 54784 | |
| KEGG | hsa:54784 | |
| UCSC | uc003uzl.3 | |
| CTD | 54784 | |
| GeneCards | GC07M102096 | |
| HGNC | HGNC:21900 | |
| HPA | HPA051422 | |
| MIM | 613302 | |
| neXtProt | NX_Q9NXW9 | |
| PharmGKB | PA143485294 | |
| eggNOG | NOG255556 | |
| GeneTree | ENSGT00390000006344 | |
| HOGENOM | HOG000015835 | |
| HOVERGEN | HBG062006 | |
| InParanoid | Q9NXW9 | |
| KO | K10766 | |
| OMA | CKGVRTC | |
| OrthoDB | EOG73Z2V0 | |
| PhylomeDB | Q9NXW9 | |
| TreeFam | TF314885 | |
| GenomeRNAi | 54784 | |
| NextBio | 57445 | |
| PRO | PR:Q9NXW9 | |
| Proteomes | UP000005640 | |
| Bgee | Q9NXW9 | |
| CleanEx | HS_ALKBH4 | |
| Genevestigator | Q9NXW9 | |
| GO | GO:0070938 GO:0005737 GO:0030496 GO:0005634 GO:0003779 GO:0032451 GO:0046872 GO:0016706 GO:0031032 GO:0036090 GO:0006482 GO:0006355 GO:0006351 | |
| Gene3D | 2.60.120.590 | |
| InterPro | IPR027450 IPR005123 | |
| Pfam | PF03171 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0031991 |
regulation of actomyosin contractile ring contraction |
ECO:0000314 |
P |
regulation of actomyosin activity |
complete | |||||
|
part_of |
GO:0070938 |
contractile ring |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0036090 |
cleavage furrow ingression |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0031032 |
actomyosin structure organization |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0030496 |
midbody |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016706 |
2-oxoglutarate-dependent dioxygenase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006482 |
protein demethylation |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003779 |
actin binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0070989 |
oxidative demethylation |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000279524 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0070938 |
contractile ring |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002647352 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0032451 |
demethylase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000279524 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0031032 |
actomyosin structure organization |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002647352 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0030496 |
midbody |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002647352 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0016491 |
oxidoreductase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000279524 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006482 |
protein demethylation |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002647352 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003779 |
actin binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN002647352 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0070988 |
demethylation |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0032451 |
demethylase activity |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003779 |
actin binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016491 |
oxidoreductase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0051213 |
dioxygenase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0030496 |
midbody |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 Li, MM et al. (2013) ALKBH4-dependent demethylation of actin regulates actomyosin dynamics. Nat Commun 4 1832 PubMed GONUTS page
- ↑ Bjørnstad, LG et al. (2011) Spectroscopic and magnetic studies of wild-type and mutant forms of the Fe(II)- and 2-oxoglutarate-dependent decarboxylase ALKBH4. Biochem. J. 434 391-8 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 3.4 3.5 3.6 3.7 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
