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MOUSE:ALKB7

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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Alkbh7 (synonyms: Spata11)
Protein Name(s) Alpha-ketoglutarate-dependent dioxygenase alkB homolog 7, mitochondrial

Alkylated DNA repair protein alkB homolog 7

External Links
UniProt Q9D6Z0
EMBL AK007380
AK009812
AK010930
GL456179
BC029677
CCDS CCDS28921.1
CCDS57105.1
RefSeq NP_079814.1
NP_081648.1
UniGene Mm.196150
ProteinModelPortal Q9D6Z0
SMR Q9D6Z0
STRING 10090.ENSMUSP00000002737
MaxQB Q9D6Z0
PaxDb Q9D6Z0
PRIDE Q9D6Z0
Ensembl ENSMUST00000002737
ENSMUST00000074141
GeneID 66400
KEGG mmu:66400
UCSC uc008ddn.2
uc012avz.1
CTD 84266
MGI MGI:1913650
eggNOG NOG299394
GeneTree ENSGT00390000014585
HOGENOM HOG000018442
HOVERGEN HBG054357
InParanoid Q9D6Z0
KO K10769
OMA SHWDDAI
OrthoDB EOG7M0NT9
PhylomeDB Q9D6Z0
TreeFam TF314197
NextBio 321567
PRO PR:Q9D6Z0
Proteomes UP000000589
Bgee Q9D6Z0
CleanEx MM_ALKBH7
Genevestigator Q9D6Z0
GO GO:0005759
GO:0005739
GO:0051213
GO:0046872
GO:0006974
GO:0006631
GO:0010883
GO:1902445
Gene3D 2.60.120.590
InterPro IPR027450
Pfam PF13532

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0005759

mitochondrial matrix

PMID:23572141[1]

ECO:0000314

C

Figure 1 shows the subcellular localization of Alkbh7 in mouse.

complete
CACAO 7842

part_of

GO:0005759

mitochondrial matrix

PMID:23572141[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:1902445

regulation of mitochondrial membrane permeability involved in programmed necrotic cell death

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9BT30

P

Seeded From UniProt

complete

involved_in

GO:0010883

regulation of lipid storage

PMID:23572141[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0006974

cellular response to DNA damage stimulus

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q9BT30

P

Seeded From UniProt

complete

involved_in

GO:0006631

fatty acid metabolic process

PMID:23572141[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005759

mitochondrial matrix

PMID:23572141[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:1902445

regulation of mitochondrial membrane permeability involved in programmed necrotic cell death

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q9BT30

P

Seeded From UniProt

complete

NOT|enables

GO:0016706

2-oxoglutarate-dependent dioxygenase activity

PMID:16174769[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0006974

cellular response to DNA damage stimulus

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q9BT30

P

Seeded From UniProt

complete

part_of

GO:0005759

mitochondrial matrix

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q9BT30

C

Seeded From UniProt

complete

part_of

GO:0005739

mitochondrion

PMID:18614015[3]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:1902445

regulation of mitochondrial membrane permeability involved in programmed necrotic cell death

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9BT30
ensembl:ENSP00000245812

P

Seeded From UniProt

complete

involved_in

GO:0006974

cellular response to DNA damage stimulus

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9BT30
ensembl:ENSP00000245812

P

Seeded From UniProt

complete

part_of

GO:0005759

mitochondrial matrix

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q9BT30
ensembl:ENSP00000245812

C

Seeded From UniProt

complete

part_of

GO:0005759

mitochondrial matrix

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR032870

C

Seeded From UniProt

complete

involved_in

GO:0006974

cellular response to DNA damage stimulus

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR032870

P

Seeded From UniProt

complete

involved_in

GO:1902445

regulation of mitochondrial membrane permeability involved in programmed necrotic cell death

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR032870

P

Seeded From UniProt

complete

involved_in

GO:0012501

programmed cell death

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1210

P

Seeded From UniProt

complete

involved_in

GO:0055114

oxidation-reduction process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0560

P

Seeded From UniProt

complete

enables

GO:0051213

dioxygenase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0223

F

Seeded From UniProt

complete

enables

GO:0016491

oxidoreductase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0560

F

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

part_of

GO:0005739

mitochondrion

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0496

C

Seeded From UniProt

complete

part_of

GO:0005759

mitochondrial matrix

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0170

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 Solberg, A et al. (2013) Deletion of mouse Alkbh7 leads to obesity. J Mol Cell Biol 5 194-203 PubMed GONUTS page
  2. Lee, DH et al. (2005) Repair of methylation damage in DNA and RNA by mammalian AlkB homologues. J. Biol. Chem. 280 39448-59 PubMed GONUTS page
  3. Pagliarini, DJ et al. (2008) A mitochondrial protein compendium elucidates complex I disease biology. Cell 134 112-23 PubMed GONUTS page