CUPPJ:TFDA

Species (Taxon ID)	Cupriavidus pinatubonensis (strain JMP 134 / LMG 1197) (Ralstoniaeutropha (strain JMP 134)). (264198)
Gene Name(s)	tfdA
Protein Name(s)	Alpha-ketoglutarate-dependent 2,4-dichlorophenoxyacetate dioxygenase 2,4-D dioxygenase
External Links
UniProt	P10088
EMBL	M16730 AY365053 EU827467 CP000093
PIR	A27082
RefSeq	YP_293634.1
PDB	1GQX
PDBsum	1GQX
ProteinModelPortal	P10088
STRING	264198.Reut_D6479
EnsemblBacteria	AAZ65777
GeneID	3607903
KEGG	reu:Reut_D6479
PATRIC	20225338
eggNOG	COG2175
HOGENOM	HOG000165071
KO	K06912
OMA	ETEFANS
OrthoDB	EOG6X3W37
BioCyc	CPIN264198:GIW3-6565-MONOMER MetaCyc:MONOMER-14384
UniPathway	UPA00685
Proteomes	UP000002697
GO	GO:0051213 GO:0031418 GO:0046872 GO:0046300
InterPro	IPR003819
Pfam	PF02668

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
Contributes to	GO:0018602	2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity	PMID:3036764	ECO:0000314			F		TfdA codes for the 2,4-D monooxygenase. Figure 4 shows omega mutagenesis of the tfdA gene. An omega fragment containing stop signals was inserted into the coding region of a tfdA plasmid. The results were a truncated tfdA product for the plasmids which the omega fragment was inserted, in turn disrupting the enzymatic activity for the 2,4-D monooxygenase.	complete CACAO 4728
enables	GO:0016491	oxidoreductase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR003819	F		Seeded From UniProt	complete
involved_in	GO:0055114	oxidation-reduction process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR003819	P		Seeded From UniProt	complete
enables	GO:0031418	L-ascorbic acid binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0847	F		Seeded From UniProt	complete
involved_in	GO:0055114	oxidation-reduction process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0560	P		Seeded From UniProt	complete
enables	GO:0016491	oxidoreductase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0560	F		Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F		Seeded From UniProt	complete
enables	GO:0051213	dioxygenase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0223	F		Seeded From UniProt	complete
involved_in	GO:0019439	aromatic compound catabolic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0058	P		Seeded From UniProt	complete
involved_in	GO:0046300	2,4-dichlorophenoxyacetic acid catabolic process	GO_REF:0000041	ECO:0000322	imported manually asserted information used in automatic assertion	UniPathway:UPA00685	P		Seeded From UniProt	complete
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References

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