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MOUSE:BCDO1
Contents
| Species (Taxon ID) | Mus musculus (Mouse). (10090) | |
| Gene Name(s) | Bco1 (ECO:0000250 with UniProtKB:Q9HAY6) (synonyms: Bcdo, Bcdo1, Bcmo1 (ECO:0000312 with MGI:MGI:1926923)) | |
| Protein Name(s) | Beta,beta-carotene 15,15'-monooxygenase
Beta-carotene dioxygenase 1 Beta-carotene oxygenase 1 (ECO:0000250 with UniProtKB:Q9HAY6) | |
| External Links | ||
| UniProt | Q9JJS6 | |
| EMBL | AJ278064 AF271298 AF294899 AY114302 AY114294 AY114295 AY114296 AY114297 AY114298 AY114299 AY114300 AY114301 AK054171 | |
| CCDS | CCDS22697.1 | |
| RefSeq | NP_067461.2 | |
| UniGene | Mm.174133 | |
| ProteinModelPortal | Q9JJS6 | |
| SMR | Q9JJS6 | |
| STRING | 10090.ENSMUSP00000034308 | |
| PhosphoSite | Q9JJS6 | |
| MaxQB | Q9JJS6 | |
| PRIDE | Q9JJS6 | |
| Ensembl | ENSMUST00000034308 | |
| GeneID | 63857 | |
| KEGG | mmu:63857 | |
| UCSC | uc009now.2 | |
| CTD | 53630 | |
| MGI | MGI:1926923 | |
| eggNOG | COG3670 | |
| GeneTree | ENSGT00500000044783 | |
| HOGENOM | HOG000232156 | |
| HOVERGEN | HBG050679 | |
| InParanoid | Q9JJS6 | |
| KO | K00515 | |
| OMA | NIMRCGE | |
| OrthoDB | EOG7353WB | |
| PhylomeDB | Q9JJS6 | |
| TreeFam | TF314019 | |
| BRENDA | 1.14.99.36 | |
| Reactome | REACT_198569 | |
| SABIO-RK | Q9JJS6 | |
| UniPathway | UPA00912 | |
| NextBio | 319783 | |
| PRO | PR:Q9JJS6 | |
| Proteomes | UP000000589 | |
| Bgee | Q9JJS6 | |
| CleanEx | MM_BCMO1 | |
| ExpressionAtlas | Q9JJS6 | |
| Genevestigator | Q9JJS6 | |
| GO | GO:0003834 GO:0046872 GO:0004497 GO:0001523 GO:0042572 | |
| InterPro | IPR004294 | |
| PANTHER | PTHR10543 | |
| Pfam | PF03055 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0003834 |
beta-carotene 15,15'-monooxygenase activity |
ECO:0000314 |
F |
Figure 3:Effect of protein, time, and substrate concentration on all-trans-retinal production by recombinant mouse carotene 15,15′-dioxygenase. |
complete | |||||
|
enables |
GO:0003834 |
beta-carotene 15,15'-monooxygenase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0001523 |
retinoid metabolic process |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0042574 |
retinal metabolic process |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0002937 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0016121 |
carotene catabolic process |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:2177469 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0010436 |
carotenoid dioxygenase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0002937 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004744 |
retinal isomerase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0002937 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003834 |
beta-carotene 15,15'-monooxygenase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0002937 |
F |
Seeded From UniProt |
complete | ||
|
acts_upstream_of_or_within |
GO:1901810 |
beta-carotene metabolic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:3767552 |
P |
occurs_in:(EMAPA:32874) |
Seeded From UniProt |
complete | |
|
acts_upstream_of_or_within |
GO:0042574 |
retinal metabolic process |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
MGI:MGI:2177469 |
P |
occurs_in:(EMAPA:32874) |
Seeded From UniProt |
complete | |
|
enables |
GO:0003834 |
beta-carotene 15,15'-monooxygenase activity |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003834 |
beta-carotene 15,15'-monooxygenase activity |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:70981 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003834 |
beta-carotene 15,15'-monooxygenase activity |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
Missing: with/from | |||
|
acts_upstream_of_or_within |
GO:0001523 |
retinoid metabolic process |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0001523 |
retinoid metabolic process |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:70981 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003834 |
beta-carotene 15,15'-monooxygenase activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9HAY6 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0001523 |
retinoid metabolic process |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9HAY6 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0016702 |
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016491 |
oxidoreductase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0051213 |
dioxygenase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0042572 |
retinol metabolic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniPathway:UPA00912 |
P |
Seeded From UniProt |
complete | ||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Paik, J et al. (2001) Expression and characterization of a murine enzyme able to cleave beta-carotene. The formation of retinoids. J. Biol. Chem. 276 32160-8 PubMed GONUTS page
- ↑ 2.0 2.1 Redmond, TM et al. (2001) Identification, expression, and substrate specificity of a mammalian beta-carotene 15,15'-dioxygenase. J. Biol. Chem. 276 6560-5 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 3.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ 4.0 4.1 Widjaja-Adhi, MA et al. (2015) A genetic dissection of intestinal fat-soluble vitamin and carotenoid absorption. Hum. Mol. Genet. 24 3206-19 PubMed GONUTS page
- ↑ Wyss, A et al. (2000) Cloning and expression of beta,beta-carotene 15,15'-dioxygenase. Biochem. Biophys. Res. Commun. 271 334-6 PubMed GONUTS page
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