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Category:GO:0006099 ! tricarboxylic acid cycle
name: tricarboxylic acid cycle
namespace: biological_process
def: "A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle." [ISBN:0198506732]
synonym: "citric acid cycle" EXACT []
synonym: "Krebs cycle" EXACT []
synonym: "oxidative TCA cycle" EXACT []
synonym: "TCA cycle" EXACT []
xref: MetaCyc:P105-PWY
xref: MetaCyc:PWY-5690
xref: MetaCyc:PWY-5913
xref: MetaCyc:PWY-6969
xref: MetaCyc:PWY-7254
xref: MetaCyc:PWY66-398
xref: MetaCyc:REDCITCYC
xref: MetaCyc:TCA
xref: MetaCyc:TCA-1
xref: Wikipedia:Tricarboxylic_acid_cycle
is_a: GO:0044238 ! primary metabolic process
relationship: part_of: GO:0009060 ! aerobic respiration
AmiGO
<GOterm>GO:0006099</GOterm>
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