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DROME:Q9VIE8
Contents
Species (Taxon ID) | Drosophila melanogaster (Fruit fly). (7227) | |
Gene Name(s) | No Information Provided. (synonyms: mAc (ECO:0000313 with EMBL:CAB93521.1)) | |
Protein Name(s) | Aconitase, isoform B (ECO:0000313 with EMBL:AAF53973.2)
Aconitase, isoform D (ECO:0000313 with EMBL:ACZ94316.1) Aconitase, isoform E (ECO:0000313 with EMBL:ABV53697.2) Aconitase, isoform F (ECO:0000313 with EMBL:AHN54633.1) LD24561p (ECO:0000313 with EMBL:AAK93129.1) Mitochondrial aconitase (ECO:0000313 with EMBL:CAB93521.1) | |
External Links | ||
UniProt | Q9VIE8 | |
EMBL | AE014134 AY051705 AE014134 AE014134 AE014134 AJ252018 | |
RefSeq | NP_001163030.1 NP_524708.1 | |
UniGene | Dm.7227 | |
SMR | Q9VIE8 | |
IntAct | Q9VIE8 | |
MINT | MINT-994599 | |
EnsemblMetazoa | FBtr0081473 FBtr0300425 | |
GeneID | 44149 | |
KEGG | dme:Dmel_CG9244 | |
UCSC | CG9244-RB | |
CTD | 44149 | |
FlyBase | FBgn0010100 | |
GeneTree | ENSGT00760000119287 | |
KO | K01681 | |
OMA | PLKCIIK | |
PhylomeDB | Q9VIE8 | |
Reactome | REACT_218888 | |
ChiTaRS | Acon | |
GenomeRNAi | 44149 | |
NextBio | 836873 | |
PRO | PR:Q9VIE8 | |
Proteomes | UP000000803 | |
GO | GO:0005811 GO:0005739 GO:0051539 GO:0003994 GO:0006099 | |
Gene3D | 3.20.19.10 3.30.499.10 3.40.1060.10 | |
InterPro | IPR015931 IPR015937 IPR001030 IPR015928 IPR015932 IPR018136 IPR006248 IPR000573 | |
PANTHER | PTHR11670 | |
Pfam | PF00330 PF00694 | |
PRINTS | PR00415 | |
SUPFAM | SSF52016 SSF53732 | |
TIGRFAMs | TIGR01340 | |
PROSITE | PS00450 PS01244 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
Contributes to |
GO:0003994 |
aconitate hydratase activity |
ECO:0000314 |
F |
Found in fruit flies and pathogenic to plants; floats in the cytosol of bacteria. |
complete | ||||
enables |
GO:0051539 |
4 iron, 4 sulfur cluster binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG12316 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0006099 |
tricarboxylic acid cycle |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0010100 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005829 |
cytosol |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG12316 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005739 |
mitochondrion |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0010100 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0003994 |
aconitate hydratase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG12316 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0005739 |
mitochondrion |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005739 |
mitochondrion |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006099 |
tricarboxylic acid cycle |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005739 |
mitochondrion |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0003994 |
aconitate hydratase activity |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0003994 |
aconitate hydratase activity |
ECO:0000303 |
author statement without traceable support used in manual assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005739 |
mitochondrion |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0003994 |
aconitate hydratase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006099 |
tricarboxylic acid cycle |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0051539 |
4 iron, 4 sulfur cluster binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005739 |
mitochondrion |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0046872 |
metal ion binding |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0051536 |
iron-sulfur cluster binding |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0016829 |
lyase activity |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005739 |
mitochondrion |
ECO:0000323 |
imported automatically asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0051539 |
4 iron, 4 sulfur cluster binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000137797 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0046872 |
metal ion binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
UniRule:UR000137797 |
F |
Seeded From UniProt |
complete | ||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Kirchberg, J et al. (2012) Aconitase B is required for optimal growth of Xanthomonas campestris pv. vesicatoria in pepper plants. PLoS ONE 7 e34941 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ Tan, DJ et al. (2009) Mapping organelle proteins and protein complexes in Drosophila melanogaster. J. Proteome Res. 8 2667-78 PubMed GONUTS page
- ↑ Esposito, G et al. (2013) Aconitase causes iron toxicity in Drosophila pink1 mutants. PLoS Genet. 9 e1003478 PubMed GONUTS page
- ↑ Cheng, Z et al. (2013) Impaired energy metabolism in a Drosophila model of mitochondrial aconitase deficiency. Biochem. Biophys. Res. Commun. 433 145-50 PubMed GONUTS page
- ↑ Zou, S et al. (2000) Genome-wide study of aging and oxidative stress response in Drosophila melanogaster. Proc. Natl. Acad. Sci. U.S.A. 97 13726-31 PubMed GONUTS page
- ↑ Alonso, J et al. () Characterization of the Drosophila melanogaster mitochondrial proteome. J. Proteome Res. 4 1636-45 PubMed GONUTS page