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DROME:Q9VIE8

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Species (Taxon ID) Drosophila melanogaster (Fruit fly). (7227)
Gene Name(s) No Information Provided. (synonyms: mAc (ECO:0000313 with EMBL:CAB93521.1))
Protein Name(s) Aconitase, isoform B (ECO:0000313 with EMBL:AAF53973.2)

Aconitase, isoform D (ECO:0000313 with EMBL:ACZ94316.1) Aconitase, isoform E (ECO:0000313 with EMBL:ABV53697.2) Aconitase, isoform F (ECO:0000313 with EMBL:AHN54633.1) LD24561p (ECO:0000313 with EMBL:AAK93129.1) Mitochondrial aconitase (ECO:0000313 with EMBL:CAB93521.1)

External Links
UniProt Q9VIE8
EMBL AE014134
AY051705
AE014134
AE014134
AE014134
AJ252018
RefSeq NP_001163030.1
NP_524708.1
UniGene Dm.7227
SMR Q9VIE8
IntAct Q9VIE8
MINT MINT-994599
EnsemblMetazoa FBtr0081473
FBtr0300425
GeneID 44149
KEGG dme:Dmel_CG9244
UCSC CG9244-RB
CTD 44149
FlyBase FBgn0010100
GeneTree ENSGT00760000119287
KO K01681
OMA PLKCIIK
PhylomeDB Q9VIE8
Reactome REACT_218888
ChiTaRS Acon
GenomeRNAi 44149
NextBio 836873
PRO PR:Q9VIE8
Proteomes UP000000803
GO GO:0005811
GO:0005739
GO:0051539
GO:0003994
GO:0006099
Gene3D 3.20.19.10
3.30.499.10
3.40.1060.10
InterPro IPR015931
IPR015937
IPR001030
IPR015928
IPR015932
IPR018136
IPR006248
IPR000573
PANTHER PTHR11670
Pfam PF00330
PF00694
PRINTS PR00415
SUPFAM SSF52016
SSF53732
TIGRFAMs TIGR01340
PROSITE PS00450
PS01244

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status

Contributes to

GO:0003994

aconitate hydratase activity

PMID:22493725[1]

IDA: Inferred from Direct Assay

F

Found in fruit flies and pathogenic to plants; floats in the cytosol of bacteria.

complete
CACAO 10557

GO:0003994

aconitate hydratase activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006248

F

Seeded From UniProt

complete

GO:0003994

aconitate hydratase activity

GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:4.2.1.3

F

Seeded From UniProt

complete

GO:0003994

aconitate hydratase activity

PMID:10471706[2]

ISS: Inferred from Sequence or Structural Similarity

F

Seeded From UniProt

Missing: with/from

GO:0003994

aconitate hydratase activity

PMID:11095759[3]

NAS: Non-traceable Author Statement

F

Seeded From UniProt

complete

GO:0005739

mitochondrion

PMID:10471706[2]

ISS: Inferred from Sequence or Structural Similarity

C

Seeded From UniProt

Missing: with/from

GO:0005739

mitochondrion

PMID:16212416[4]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

complete

GO:0005739

mitochondrion

PMID:19317464[5]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

complete

GO:0005739

mitochondrion

PMID:23637640[6]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

complete

GO:0005811

lipid particle

PMID:16543254[7]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

complete

GO:0005811

lipid particle

PMID:16979555[8]

IDA: Inferred from Direct Assay

C

Seeded From UniProt

complete

GO:0006099

tricarboxylic acid cycle

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006248

P

Seeded From UniProt

complete

GO:0006099

tricarboxylic acid cycle

PMID:23438437[9]

IMP: Inferred from Mutant Phenotype

P

Seeded From UniProt

complete

GO:0008152

metabolic process

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000573
InterPro:IPR001030
InterPro:IPR015931
InterPro:IPR015932
InterPro:IPR015937

P

Seeded From UniProt

complete

GO:0016829

lyase activity

GO_REF:0000038

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0456

F

Seeded From UniProt

complete

GO:0051539

4 iron, 4 sulfur cluster binding

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006248

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Kirchberg, J et al. (2012) Aconitase B is required for optimal growth of Xanthomonas campestris pv. vesicatoria in pepper plants. PLoS ONE 7 e34941 PubMed GONUTS page
  2. 2.0 2.1 Spradling, AC et al. (1999) The Berkeley Drosophila Genome Project gene disruption project: Single P-element insertions mutating 25% of vital Drosophila genes. Genetics 153 135-77 PubMed GONUTS page
  3. Zou, S et al. (2000) Genome-wide study of aging and oxidative stress response in Drosophila melanogaster. Proc. Natl. Acad. Sci. U.S.A. 97 13726-31 PubMed GONUTS page
  4. Alonso, J et al. () Characterization of the Drosophila melanogaster mitochondrial proteome. J. Proteome Res. 4 1636-45 PubMed GONUTS page
  5. Tan, DJ et al. (2009) Mapping organelle proteins and protein complexes in Drosophila melanogaster. J. Proteome Res. 8 2667-78 PubMed GONUTS page
  6. Esposito, G et al. (2013) Aconitase causes iron toxicity in Drosophila pink1 mutants. PLoS Genet. 9 e1003478 PubMed GONUTS page
  7. Beller, M et al. (2006) Characterization of the Drosophila lipid droplet subproteome. Mol. Cell Proteomics 5 1082-94 PubMed GONUTS page
  8. Cermelli, S et al. (2006) The lipid-droplet proteome reveals that droplets are a protein-storage depot. Curr. Biol. 16 1783-95 PubMed GONUTS page
  9. Cheng, Z et al. (2013) Impaired energy metabolism in a Drosophila model of mitochondrial aconitase deficiency. Biochem. Biophys. Res. Commun. 433 145-50 PubMed GONUTS page