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Category:GO:0003994 ! aconitate hydratase activity
name: aconitate hydratase activity
namespace: molecular_function
alt_id: GO:0052632
def: "Catalysis of the reaction: citrate = isocitrate. The reaction occurs in two steps: (1) citrate = cis-aconitate + H2O, (2) cis-aconitate + H2O = isocitrate. This reaction is the interconversion of citrate and isocitrate via the labile, enzyme-bound intermediate cis-aconitate. Water is removed from one part of the citrate molecule and added back to a different atom to form isocitrate." [EC:4.2.1.3, GOC:pde, GOC:vw]
synonym: "aconitase activity" EXACT []
synonym: "cis-aconitase activity" RELATED [EC:4.2.1.3]
synonym: "citrate hydro-lyase activity" BROAD [EC:4.2.1.3]
synonym: "citrate(isocitrate) hydro-lyase (cis-aconitate-forming)" RELATED [EC:4.2.1.3]
synonym: "citrate(isocitrate) hydro-lyase activity" RELATED [EC:4.2.1.3]
xref: EC:4.2.1.3
xref: MetaCyc:RXN-14047
xref: RHEA:10336
is_a: GO:0016836 ! hydro-lyase activity
AmiGO
<GOterm>GO:0003994</GOterm>
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