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CHICK:IREB2

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) IREB2
Protein Name(s) Iron-responsive element-binding protein 2

IRE-BP 2

External Links
UniProt Q5ZLQ4
EMBL AJ719680
RefSeq NP_001026625.1
UniGene Gga.1321
ProteinModelPortal Q5ZLQ4
SMR Q5ZLQ4
STRING 9031.ENSGALP00000005019
PaxDb Q5ZLQ4
GeneID 427490
KEGG gga:427490
CTD 3658
eggNOG COG1048
HOGENOM HOG000025704
InParanoid Q5ZLQ4
PhylomeDB Q5ZLQ4
NextBio 20828741
PRO PR:Q5ZLQ4
Proteomes UP000000539
GO GO:0005737
GO:0051539
GO:0030350
GO:0046872
GO:0030371
GO:0006879
GO:0006826
GO:0008152
Gene3D 3.20.19.10
3.30.499.10
3.40.1060.10
InterPro IPR015931
IPR015937
IPR001030
IPR015928
IPR006249
IPR015932
IPR018136
IPR000573
IPR029755
PANTHER PTHR11670
PTHR11670:SF31
Pfam PF00330
PF00694
PRINTS PR00415
SUPFAM SSF52016
SSF53732
TIGRFAMs TIGR01341
PROSITE PS00450
PS01244

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:1990910

response to hypobaric hypoxia

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002617314
RGD:621539

P

Seeded From UniProt

complete

involved_in

GO:1904373

response to kainic acid

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002617314
RGD:621539

P

Seeded From UniProt

complete

involved_in

GO:0090650

cellular response to oxygen-glucose deprivation

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002617314
RGD:621539

P

Seeded From UniProt

complete

involved_in

GO:0072705

cellular response to mercaptoethanol

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002617314
RGD:621539

P

Seeded From UniProt

complete

involved_in

GO:0071456

cellular response to hypoxia

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002617314
RGD:621539

P

Seeded From UniProt

complete

involved_in

GO:0071364

cellular response to epidermal growth factor stimulus

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002617314
RGD:621539

P

Seeded From UniProt

complete

involved_in

GO:0071300

cellular response to retinoic acid

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002617314
RGD:621539

P

Seeded From UniProt

complete

involved_in

GO:0071287

cellular response to manganese ion

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002617314
RGD:621539

P

Seeded From UniProt

complete

involved_in

GO:0071283

cellular response to iron(III) ion

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002617314
RGD:621539

P

Seeded From UniProt

complete

enables

GO:0051539

4 iron, 4 sulfur cluster binding

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG11325
PANTHER:PTN000186700
RGD:621539
UniProtKB:P09339
UniProtKB:P21399
UniProtKB:Q0VCU1

F

Seeded From UniProt

complete

involved_in

GO:0046688

response to copper ion

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002617314
RGD:621539

P

Seeded From UniProt

complete

involved_in

GO:0034101

erythrocyte homeostasis

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1928268
PANTHER:PTN002617314

P

Seeded From UniProt

complete

involved_in

GO:0032526

response to retinoic acid

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002617314
RGD:621539

P

Seeded From UniProt

complete

part_of

GO:0030424

axon

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002617314
RGD:621539

C

Seeded From UniProt

complete

enables

GO:0030350

iron-responsive element binding

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1928268
PANTHER:PTN002617314
RGD:621539

F

Seeded From UniProt

complete

involved_in

GO:0030316

osteoclast differentiation

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1928268
PANTHER:PTN002617314

P

Seeded From UniProt

complete

involved_in

GO:0017148

negative regulation of translation

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002617314
RGD:621539

P

Seeded From UniProt

complete

involved_in

GO:0014823

response to activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002617314
RGD:621539

P

Seeded From UniProt

complete

involved_in

GO:0014732

skeletal muscle atrophy

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002617314
RGD:621539

P

Seeded From UniProt

complete

involved_in

GO:0010043

response to zinc ion

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002617314
RGD:621539

P

Seeded From UniProt

complete

involved_in

GO:0010041

response to iron(III) ion

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002617314
RGD:621539

P

Seeded From UniProt

complete

involved_in

GO:0010040

response to iron(II) ion

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002617314
RGD:621539

P

Seeded From UniProt

complete

involved_in

GO:0009791

post-embryonic development

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1928268
PANTHER:PTN002617314

P

Seeded From UniProt

complete

involved_in

GO:0007568

aging

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002617314
RGD:621539

P

Seeded From UniProt

complete

involved_in

GO:0007420

brain development

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002617314
RGD:621539

P

Seeded From UniProt

complete

involved_in

GO:0006879

cellular iron ion homeostasis

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1928268
PANTHER:PTN002617314

P

Seeded From UniProt

complete

involved_in

GO:0006782

protoporphyrinogen IX biosynthetic process

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1928268
PANTHER:PTN002617314

P

Seeded From UniProt

complete

involved_in

GO:0006417

regulation of translation

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1928268
PANTHER:PTN002617314

P

Seeded From UniProt

complete

involved_in

GO:0006101

citrate metabolic process

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000186700
TAIR:locus:2116297
UniProtKB:P21399
UniProtKB:Q0VCU1
UniProtKB:Q42560

P

Seeded From UniProt

complete

involved_in

GO:0006099

tricarboxylic acid cycle

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000186700
UniProtKB:Q8ZP52

P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG11325
MGI:MGI:1928268
MGI:MGI:87879
PANTHER:PTN000186700
RGD:2019
RGD:621539
UniProtKB:P21399
UniProtKB:Q42560
UniProtKB:Q8IDR8
WB:WBGene00000040

C

Seeded From UniProt

complete

part_of

GO:0005739

mitochondrion

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002268875
TAIR:locus:2116297
UniProtKB:P21399
UniProtKB:Q42560
UniProtKB:Q8IDR8

C

Seeded From UniProt

complete

enables

GO:0003994

aconitate hydratase activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG11325
FB:FBgn0024957
FB:FBgn0024958
MGI:MGI:87879
PANTHER:PTN000186700
RGD:2019
TAIR:locus:2063354
TAIR:locus:2116297
UniProtKB:P09339
UniProtKB:P21399
UniProtKB:Q0VCU1
UniProtKB:Q42560
UniProtKB:Q8IDR8
UniProtKB:Q8ZP52
WB:WBGene00000040

F

Seeded From UniProt

complete

enables

GO:0001069

regulatory region RNA binding

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002617314
RGD:621539

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR029755

C

Seeded From UniProt

complete

involved_in

GO:0006879

cellular iron ion homeostasis

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR029755

P

Seeded From UniProt

complete

involved_in

GO:0017148

negative regulation of translation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR029755

P

Seeded From UniProt

complete

enables

GO:0030350

iron-responsive element binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR029755

F

Seeded From UniProt

complete

enables

GO:0030371

translation repressor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR029755

F

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

enables

GO:0051539

4 iron, 4 sulfur cluster binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0004

F

Seeded From UniProt

complete

enables

GO:0003723

RNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0694

F

Seeded From UniProt

complete

enables

GO:0051536

iron-sulfur cluster binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0411

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. ↑ 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 1.13 1.14 1.15 1.16 1.17 1.18 1.19 1.20 1.21 1.22 1.23 1.24 1.25 1.26 1.27 1.28 1.29 1.30 1.31 1.32 1.33 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page