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CHICK:IREB2

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Species (Taxon ID) Gallus gallus (Chicken). (9031)
Gene Name(s) IREB2
Protein Name(s) Iron-responsive element-binding protein 2

IRE-BP 2

External Links
UniProt Q5ZLQ4
EMBL AJ719680
RefSeq NP_001026625.1
UniGene Gga.1321
ProteinModelPortal Q5ZLQ4
SMR Q5ZLQ4
STRING 9031.ENSGALP00000005019
PaxDb Q5ZLQ4
GeneID 427490
KEGG gga:427490
CTD 3658
eggNOG COG1048
HOGENOM HOG000025704
InParanoid Q5ZLQ4
PhylomeDB Q5ZLQ4
NextBio 20828741
PRO PR:Q5ZLQ4
Proteomes UP000000539
GO GO:0005737
GO:0051539
GO:0030350
GO:0046872
GO:0030371
GO:0006879
GO:0006826
GO:0008152
Gene3D 3.20.19.10
3.30.499.10
3.40.1060.10
InterPro IPR015931
IPR015937
IPR001030
IPR015928
IPR006249
IPR015932
IPR018136
IPR000573
IPR029755
PANTHER PTHR11670
PTHR11670:SF31
Pfam PF00330
PF00694
PRINTS PR00415
SUPFAM SSF52016
SSF53732
TIGRFAMs TIGR01341
PROSITE PS00450
PS01244

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:1990910

response to hypobaric hypoxia

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002617314
RGD:621539

P

Seeded From UniProt

complete

involved_in

GO:1904373

response to kainic acid

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002617314
RGD:621539

P

Seeded From UniProt

complete

involved_in

GO:0090650

cellular response to oxygen-glucose deprivation

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002617314
RGD:621539

P

Seeded From UniProt

complete

involved_in

GO:0072705

cellular response to mercaptoethanol

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002617314
RGD:621539

P

Seeded From UniProt

complete

involved_in

GO:0071456

cellular response to hypoxia

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002617314
RGD:621539

P

Seeded From UniProt

complete

involved_in

GO:0071364

cellular response to epidermal growth factor stimulus

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002617314
RGD:621539

P

Seeded From UniProt

complete

involved_in

GO:0071300

cellular response to retinoic acid

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002617314
RGD:621539

P

Seeded From UniProt

complete

involved_in

GO:0071287

cellular response to manganese ion

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002617314
RGD:621539

P

Seeded From UniProt

complete

involved_in

GO:0071283

cellular response to iron(III) ion

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002617314
RGD:621539

P

Seeded From UniProt

complete

enables

GO:0051539

4 iron, 4 sulfur cluster binding

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG11325
PANTHER:PTN000186700
RGD:621539
UniProtKB:P09339
UniProtKB:P21399
UniProtKB:Q0VCU1

F

Seeded From UniProt

complete

involved_in

GO:0046688

response to copper ion

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002617314
RGD:621539

P

Seeded From UniProt

complete

involved_in

GO:0034101

erythrocyte homeostasis

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1928268
PANTHER:PTN002617314

P

Seeded From UniProt

complete

involved_in

GO:0032526

response to retinoic acid

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002617314
RGD:621539

P

Seeded From UniProt

complete

part_of

GO:0030424

axon

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002617314
RGD:621539

C

Seeded From UniProt

complete

enables

GO:0030350

iron-responsive element binding

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1928268
PANTHER:PTN002617314
RGD:621539

F

Seeded From UniProt

complete

involved_in

GO:0030316

osteoclast differentiation

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1928268
PANTHER:PTN002617314

P

Seeded From UniProt

complete

involved_in

GO:0017148

negative regulation of translation

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002617314
RGD:621539

P

Seeded From UniProt

complete

involved_in

GO:0014823

response to activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002617314
RGD:621539

P

Seeded From UniProt

complete

involved_in

GO:0014732

skeletal muscle atrophy

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002617314
RGD:621539

P

Seeded From UniProt

complete

involved_in

GO:0010043

response to zinc ion

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002617314
RGD:621539

P

Seeded From UniProt

complete

involved_in

GO:0010041

response to iron(III) ion

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002617314
RGD:621539

P

Seeded From UniProt

complete

involved_in

GO:0010040

response to iron(II) ion

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002617314
RGD:621539

P

Seeded From UniProt

complete

involved_in

GO:0009791

post-embryonic development

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1928268
PANTHER:PTN002617314

P

Seeded From UniProt

complete

involved_in

GO:0007568

aging

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002617314
RGD:621539

P

Seeded From UniProt

complete

involved_in

GO:0007420

brain development

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002617314
RGD:621539

P

Seeded From UniProt

complete

involved_in

GO:0006879

cellular iron ion homeostasis

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1928268
PANTHER:PTN002617314

P

Seeded From UniProt

complete

involved_in

GO:0006782

protoporphyrinogen IX biosynthetic process

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1928268
PANTHER:PTN002617314

P

Seeded From UniProt

complete

involved_in

GO:0006417

regulation of translation

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1928268
PANTHER:PTN002617314

P

Seeded From UniProt

complete

involved_in

GO:0006101

citrate metabolic process

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000186700
TAIR:locus:2116297
UniProtKB:P21399
UniProtKB:Q0VCU1
UniProtKB:Q42560

P

Seeded From UniProt

complete

involved_in

GO:0006099

tricarboxylic acid cycle

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000186700
UniProtKB:Q8ZP52

P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG11325
MGI:MGI:1928268
MGI:MGI:87879
PANTHER:PTN000186700
RGD:2019
RGD:621539
UniProtKB:P21399
UniProtKB:Q42560
UniProtKB:Q8IDR8
WB:WBGene00000040

C

Seeded From UniProt

complete

part_of

GO:0005739

mitochondrion

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002268875
TAIR:locus:2116297
UniProtKB:P21399
UniProtKB:Q42560
UniProtKB:Q8IDR8

C

Seeded From UniProt

complete

enables

GO:0003994

aconitate hydratase activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG11325
FB:FBgn0024957
FB:FBgn0024958
MGI:MGI:87879
PANTHER:PTN000186700
RGD:2019
TAIR:locus:2063354
TAIR:locus:2116297
UniProtKB:P09339
UniProtKB:P21399
UniProtKB:Q0VCU1
UniProtKB:Q42560
UniProtKB:Q8IDR8
UniProtKB:Q8ZP52
WB:WBGene00000040

F

Seeded From UniProt

complete

enables

GO:0001069

regulatory region RNA binding

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002617314
RGD:621539

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR029755

C

Seeded From UniProt

complete

involved_in

GO:0006879

cellular iron ion homeostasis

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR029755

P

Seeded From UniProt

complete

involved_in

GO:0017148

negative regulation of translation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR029755

P

Seeded From UniProt

complete

enables

GO:0030350

iron-responsive element binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR029755

F

Seeded From UniProt

complete

enables

GO:0030371

translation repressor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR029755

F

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

enables

GO:0051539

4 iron, 4 sulfur cluster binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0004

F

Seeded From UniProt

complete

enables

GO:0003723

RNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0694

F

Seeded From UniProt

complete

enables

GO:0051536

iron-sulfur cluster binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0411

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 1.13 1.14 1.15 1.16 1.17 1.18 1.19 1.20 1.21 1.22 1.23 1.24 1.25 1.26 1.27 1.28 1.29 1.30 1.31 1.32 1.33 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page