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ECOLI:ACON1
Contents
| Species (Taxon ID) | Escherichia coli (strain K12). (83333) | |
| Gene Name(s) | acnA (synonyms: acn) | |
| Protein Name(s) | Aconitate hydratase 1
Aconitase 1 Citrate hydro-lyase 1 | |
| External Links | ||
| UniProt | P25516 | |
| EMBL | X60293 U00096 AP009048 | |
| PIR | G64875 | |
| RefSeq | NP_415792.1 YP_489544.1 | |
| ProteinModelPortal | P25516 | |
| SMR | P25516 | |
| BioGrid | 851065 | |
| DIP | DIP-9043N | |
| IntAct | P25516 | |
| MINT | MINT-1249275 | |
| STRING | 511145.b1276 | |
| PaxDb | P25516 | |
| PRIDE | P25516 | |
| EnsemblBacteria | AAC74358 BAA14828 | |
| GeneID | 12931140 946724 | |
| KEGG | ecj:Y75_p1251 eco:b1276 | |
| PATRIC | 32117814 | |
| EchoBASE | EB1301 | |
| EcoGene | EG11325 | |
| eggNOG | COG1048 | |
| HOGENOM | HOG000025704 | |
| InParanoid | P25516 | |
| KO | K01681 | |
| OMA | EHVENLA | |
| OrthoDB | EOG67DPHM | |
| PhylomeDB | P25516 | |
| BioCyc | EcoCyc:ACONITASE-MONOMER ECOL316407:JW1268-MONOMER MetaCyc:ACONITASE-MONOMER | |
| UniPathway | UPA00223 | |
| PRO | PR:P25516 | |
| Proteomes | UP000000318 UP000000625 | |
| Genevestigator | P25516 | |
| GO | GO:0005737 GO:0051539 GO:0003994 GO:0005506 GO:0046872 GO:0003730 GO:0003729 GO:0009061 GO:0006097 GO:0006979 GO:0006099 | |
| Gene3D | 3.20.19.10 3.30.499.10 3.40.1060.10 | |
| InterPro | IPR015931 IPR015937 IPR001030 IPR015928 IPR015934 IPR006249 IPR015932 IPR018136 IPR000573 | |
| PANTHER | PTHR11670 PTHR11670:SF1 | |
| Pfam | PF00330 PF00694 | |
| PRINTS | PR00415 | |
| SUPFAM | SSF52016 SSF53732 | |
| TIGRFAMs | TIGR01341 | |
| PROSITE | PS00450 PS01244 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
enables |
GO:0051539 |
4 iron, 4 sulfur cluster binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG11325 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006101 |
citrate metabolic process |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000186700 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006099 |
tricarboxylic acid cycle |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000186700 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG11325 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003994 |
aconitate hydratase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG11325 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003994 |
aconitate hydratase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG11325 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0051539 |
4 iron, 4 sulfur cluster binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009061 |
anaerobic respiration |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006979 |
response to oxidative stress |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006099 |
tricarboxylic acid cycle |
ECO:0000303 |
author statement without traceable support used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006097 |
glyoxylate cycle |
ECO:0000303 |
author statement without traceable support used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005506 |
iron ion binding |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003994 |
aconitate hydratase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003729 |
mRNA binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0051539 |
4 iron, 4 sulfur cluster binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003994 |
aconitate hydratase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003730 |
mRNA 3'-UTR binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003994 |
aconitate hydratase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016829 |
lyase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006099 |
tricarboxylic acid cycle |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniProtKB-KW:KW-0816 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0051539 |
4 iron, 4 sulfur cluster binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003723 |
RNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0051536 |
iron-sulfur cluster binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 Varghese, S et al. (2003) Contrasting sensitivities of Escherichia coli aconitases A and B to oxidation and iron depletion. J. Bacteriol. 185 221-30 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 Tang, Y & Guest, JR (1999) Direct evidence for mRNA binding and post-transcriptional regulation by Escherichia coli aconitases. Microbiology (Reading, Engl.) 145 ( Pt 11) 3069-79 PubMed GONUTS page
- ↑ Prodromou, C et al. (1991) The aconitase of Escherichia coli: purification of the enzyme and molecular cloning and map location of the gene (acn). J. Gen. Microbiol. 137 2505-15 PubMed GONUTS page
- ↑ 5.0 5.1 Bennett, B et al. (1995) Spectroscopic characterisation of an aconitase (AcnA) of Escherichia coli. Eur. J. Biochem. 233 317-26 PubMed GONUTS page
- ↑ Ishihama, Y et al. (2008) Protein abundance profiling of the Escherichia coli cytosol. BMC Genomics 9 102 PubMed GONUTS page
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