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ECOLI:IDH
Contents
| Species (Taxon ID) | Escherichia coli (strain K12). (83333) | |
| Gene Name(s) | icd (synonyms: icdA, icdE) | |
| Protein Name(s) | Isocitrate dehydrogenase [NADP]
IDH IDP NADP(+)-specific ICDH Oxalosuccinate decarboxylase | |
| External Links | ||
| UniProt | P08200 | |
| EMBL | J02799 U00096 AP009048 AF017587 | |
| PIR | A28482 | |
| RefSeq | NP_415654.1 YP_489404.1 | |
| PDB | 1AI2 1AI3 1BL5 1CW1 1CW4 1CW7 1GRO 1GRP 1HJ6 1IDC 1IDD 1IDE 1IDF 1IKA 1ISO 1P8F 1PB1 1PB3 1SJS 3ICD 3LCB 4AJ3 4AJA 4AJB 4AJC 4AJR 4AJS 4BNP 4ICD 4P69 5ICD 6ICD 7ICD 8ICD 9ICD | |
| PDBsum | 1AI2 1AI3 1BL5 1CW1 1CW4 1CW7 1GRO 1GRP 1HJ6 1IDC 1IDD 1IDE 1IDF 1IKA 1ISO 1P8F 1PB1 1PB3 1SJS 3ICD 3LCB 4AJ3 4AJA 4AJB 4AJC 4AJR 4AJS 4BNP 4ICD 4P69 5ICD 6ICD 7ICD 8ICD 9ICD | |
| ProteinModelPortal | P08200 | |
| SMR | P08200 | |
| DIP | DIP-10006N | |
| IntAct | P08200 | |
| STRING | 511145.b1136 | |
| PhosSite | P010427 | |
| SWISS-2DPAGE | P08200 | |
| PaxDb | P08200 | |
| PRIDE | P08200 | |
| EnsemblBacteria | AAC74220 BAA35958 | |
| GeneID | 12934062 945702 | |
| KEGG | ecj:Y75_p1106 eco:b1136 | |
| PATRIC | 32117521 | |
| EchoBASE | EB0484 | |
| EcoGene | EG10489 EG10009 | |
| eggNOG | COG0538 | |
| HOGENOM | HOG000021113 | |
| InParanoid | P08200 | |
| KO | K00031 | |
| OMA | FRDWGYE | |
| OrthoDB | EOG6SNDTP | |
| PhylomeDB | P08200 | |
| BioCyc | EcoCyc:ISOCITDEH-SUBUNIT ECOL316407:JW1122-MONOMER MetaCyc:ISOCITDEH-SUBUNIT | |
| SABIO-RK | P08200 | |
| EvolutionaryTrace | P08200 | |
| PRO | PR:P08200 | |
| Proteomes | UP000000318 UP000000625 | |
| Genevestigator | P08200 | |
| GO | GO:0005737 GO:0004450 GO:0000287 GO:0051287 GO:0022900 GO:0006097 GO:0006979 GO:0006099 | |
| Gene3D | 3.40.718.10 | |
| InterPro | IPR019818 IPR001804 IPR004439 IPR024084 | |
| PANTHER | PTHR11835 | |
| Pfam | PF00180 | |
| TIGRFAMs | TIGR00183 | |
| PROSITE | PS00470 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
enables |
GO:0004450 |
isocitrate dehydrogenase (NADP+) activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0022900 |
electron transport chain |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006979 |
response to oxidative stress |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000287 |
magnesium ion binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004450 |
isocitrate dehydrogenase (NADP+) activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006099 |
tricarboxylic acid cycle |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016616 |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0051287 |
NAD binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004450 |
isocitrate dehydrogenase (NADP+) activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016491 |
oxidoreductase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006097 |
glyoxylate cycle |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006099 |
tricarboxylic acid cycle |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Zhang, Z et al. (2011) Identification of lysine succinylation as a new post-translational modification. Nat. Chem. Biol. 7 58-63 PubMed GONUTS page
- ↑ Kabir, MM & Shimizu, K (2004) Metabolic regulation analysis of icd-gene knockout Escherichia coli based on 2D electrophoresis with MALDI-TOF mass spectrometry and enzyme activity measurements. Appl. Microbiol. Biotechnol. 65 84-96 PubMed GONUTS page
- ↑ Garnak, M & Reeves, HC (1979) Phosphorylation of Isocitrate dehydrogenase of Escherichia coli. Science 203 1111-2 PubMed GONUTS page
- ↑ Krisko, A et al. (2014) Inferring gene function from evolutionary change in signatures of translation efficiency. Genome Biol. 15 R44 PubMed GONUTS page
- ↑ Ishihama, Y et al. (2008) Protein abundance profiling of the Escherichia coli cytosol. BMC Genomics 9 102 PubMed GONUTS page
- ↑ Lopez-Campistrous, A et al. (2005) Localization, annotation, and comparison of the Escherichia coli K-12 proteome under two states of growth. Mol. Cell Proteomics 4 1205-9 PubMed GONUTS page
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