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ECOLI:ODO1
Contents
| Species (Taxon ID) | Escherichia coli (strain K12). (83333) | |
| Gene Name(s) | sucA | |
| Protein Name(s) | 2-oxoglutarate dehydrogenase E1 component
Alpha-ketoglutarate dehydrogenase | |
| External Links | ||
| UniProt | P0AFG3 | |
| EMBL | J01619 X00661 U00096 AP009048 | |
| PIR | E64808 | |
| RefSeq | NP_415254.1 YP_489005.1 | |
| PDB | 2JGD | |
| PDBsum | 2JGD | |
| ProteinModelPortal | P0AFG3 | |
| SMR | P0AFG3 | |
| BioGrid | 849680 | |
| DIP | DIP-36225N | |
| IntAct | P0AFG3 | |
| MINT | MINT-1243484 | |
| STRING | 511145.b0726 | |
| SWISS-2DPAGE | P0AFG3 | |
| PaxDb | P0AFG3 | |
| PRIDE | P0AFG3 | |
| EnsemblBacteria | AAC73820 BAA35392 | |
| GeneID | 12930950 945303 | |
| KEGG | ecj:Y75_p0705 eco:b0726 | |
| PATRIC | 32116647 | |
| EchoBASE | EB0972 | |
| EcoGene | EG10979 | |
| eggNOG | COG0567 | |
| HOGENOM | HOG000259587 | |
| InParanoid | P0AFG3 | |
| KO | K00164 | |
| OMA | QNQGAWF | |
| OrthoDB | EOG6V1M1F | |
| BioCyc | EcoCyc:E1O-MONOMER ECOL316407:JW0715-MONOMER MetaCyc:E1O-MONOMER | |
| EvolutionaryTrace | P0AFG3 | |
| PRO | PR:P0AFG3 | |
| Proteomes | UP000000318 UP000000625 | |
| Genevestigator | P0AFG3 | |
| GO | GO:0005829 GO:0042802 GO:0004591 GO:0030976 GO:0006096 GO:0006099 | |
| Gene3D | 3.40.50.970 | |
| InterPro | IPR011603 IPR001017 IPR029061 IPR005475 | |
| PANTHER | PTHR23152 | |
| Pfam | PF00676 PF02779 | |
| PIRSF | PIRSF000157 | |
| SMART | SM00861 | |
| SUPFAM | SSF52518 | |
| TIGRFAMs | TIGR00239 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0004591 |
oxoglutarate dehydrogenase (succinyl-transferring) activity |
ECO:0000270 |
F |
Fig. 1 shows the map for SucA in the E. Coli genome that illustrates the genes it is associated with and subsequent activity. |
complete | |||||
|
part_of |
GO:0005829 |
cytosol |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0045252 |
oxoglutarate dehydrogenase complex |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000568360 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006099 |
tricarboxylic acid cycle |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000568360 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10979 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004591 |
oxoglutarate dehydrogenase (succinyl-transferring) activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10979 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0042802 |
identical protein binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0042802 |
identical protein binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0030976 |
thiamine pyrophosphate binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004591 |
oxoglutarate dehydrogenase (succinyl-transferring) activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000287 |
magnesium ion binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004591 |
oxoglutarate dehydrogenase (succinyl-transferring) activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006099 |
tricarboxylic acid cycle |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016624 |
oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0030976 |
thiamine pyrophosphate binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004591 |
oxoglutarate dehydrogenase (succinyl-transferring) activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016491 |
oxidoreductase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000166 |
nucleotide binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006099 |
tricarboxylic acid cycle |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Darlison, MG et al. (1984) Nucleotide sequence of the sucA gene encoding the 2-oxoglutarate dehydrogenase of Escherichia coli K12. Eur. J. Biochem. 141 351-9 PubMed GONUTS page
- ↑ 2.0 2.1 Lasserre, JP et al. (2006) A complexomic study of Escherichia coli using two-dimensional blue native/SDS polyacrylamide gel electrophoresis. Electrophoresis 27 3306-21 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ Rajagopala, SV et al. (2014) The binary protein-protein interaction landscape of Escherichia coli. Nat. Biotechnol. 32 285-90 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 Frank, RA et al. (2007) Crystal structure of the E1 component of the Escherichia coli 2-oxoglutarate dehydrogenase multienzyme complex. J. Mol. Biol. 368 639-51 PubMed GONUTS page
- ↑ Ishihama, Y et al. (2008) Protein abundance profiling of the Escherichia coli cytosol. BMC Genomics 9 102 PubMed GONUTS page
b
o
- GO:0055114 ! obsolete oxidation-reduction process
- GO:0016491 ! oxidoreductase activity
- GO:0016624 ! oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
- GO:0045252 ! oxoglutarate dehydrogenase complex
- GO:0004591 ! oxoglutarate dehydrogenase (succinyl-transferring) activity
