Category:GO:0120551 ! 2-oxoglutarate decarboxylation to succinyl-CoA

name: 2-oxoglutarate decarboxylation to succinyl-CoA
namespace: biological_process
def: "The chemical reactions and pathways resulting in the formation of succinyl-CoA from 2-oxoglutarate. In most organisms, this pathway is part of the TCA cycle and comprises a series of three reactions carried out by a multisubunit complex called the '2-oxoglutarate dehydrogenase complex', even though 2-oxoglutarate dehydrogenase activity describes only one of those reactions. The combination of the three reactions can be summarized as: 2-oxoglutarate + coenzyme A + NAD+ -> succinyl-CoA + CO2 + NADH." [MetaCyc:PWY-5084]
synonym: "2-ketoglutarate dehydrogenase system" EXACT []
synonym: "2-oxoglutarate dehydrogenase system" EXACT []
synonym: "2alpha-ketoglutarate dehydrogenase system" EXACT []
xref: MetaCyc:PWY-5084
is_a: GO:0006103 ! 2-oxoglutarate metabolic process
is_a: GO:1901290 ! succinyl-CoA biosynthetic process
relationship: part_of: GO:0006099 ! tricarboxylic acid cycle

AmiGO <GOterm>GO:0120551</GOterm>
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