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Category:GO:0007254 ! JNK cascade
name: JNK cascade
namespace: biological_process
def: "An intracellular protein kinase cascade containing at least a JNK (a MAPK), a JNKK (a MAPKK) and a JUN3K (a MAP3K). The cascade can also contain an additional tier: the upstream MAP4K. The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell." [GOC:bf, GOC:signaling, PMID:11790549, PMID:20811974]
synonym: "c-Jun N-terminal kinase cascade" EXACT [PMID:20811974]
synonym: "JNK1 cascade" NARROW [GOC:add]
synonym: "JNK2 cascade" NARROW [GOC:add]
synonym: "JNK3 cascade" NARROW [GOC:add]
synonym: "MAPK10 cascade" NARROW [GOC:add]
synonym: "MAPK8 cascade" NARROW [GOC:add]
synonym: "MAPK9 cascade" NARROW [GOC:add]
synonym: "SAPK cascade" BROAD []
synonym: "stress-activated protein kinase cascade" BROAD []
is_a: GO:0051403 ! stress-activated MAPK cascade
AmiGO
<GOterm>GO:0007254</GOterm>
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This category has the following 6 subcategories, out of 6 total.
