Category:GO:0007254 ! JNK cascade

name: JNK cascade
namespace: biological_process
def: "An intracellular protein kinase cascade containing at least a JNK (a MAPK), a JNKK (a MAPKK) and a JUN3K (a MAP3K). The cascade can also contain two additional tiers: the upstream MAP4K and the downstream MAP Kinase-activated kinase (MAPKAPK). The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell." [GOC:bf, GOC:signaling, PMID:11790549, PMID:20811974]
synonym: "c-Jun N-terminal kinase cascade" EXACT [PMID:20811974]
synonym: "JNK1 cascade" NARROW [GOC:add]
synonym: "JNK2 cascade" NARROW [GOC:add]
synonym: "JNK3 cascade" NARROW [GOC:add]
synonym: "MAPK10 cascade" NARROW [GOC:add]
synonym: "MAPK8 cascade" NARROW [GOC:add]
synonym: "MAPK9 cascade" NARROW [GOC:add]
synonym: "SAPK cascade" BROAD []
synonym: "stress-activated protein kinase cascade" BROAD []
is_a: GO:0051403 ! stress-activated MAPK cascade

AmiGO

Child Terms

This category has the following 6 subcategories, out of 6 total.

• [+] GO:0007256 ! activation of JNKK activity (1)
• [+] GO:0007257 ! activation of JUN kinase activity (1)
• [+] GO:0007258 ! JUN phosphorylation (1)
• [+] GO:0042655 ! activation of JNKKK activity (1)
• [+] GO:0046328 ! regulation of JNK cascade (3)
• [+] GO:0046330 ! positive regulation of JNK cascade (1)

Pages in category "GO:0007254 ! JNK cascade"

The following 122 pages are in this category, out of 122 total.