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DROME:JIP1
Contents
| Species (Taxon ID) | Drosophila melanogaster (Fruit fly). (7227) | |
| Gene Name(s) | Aplip1 (synonyms: SP512) | |
| Protein Name(s) | JNK-interacting protein 1
JIP-1 APP-like-interacting protein 1 APLIP1 Protein eye developmental SP512 | |
| External Links | ||
| UniProt | Q9W0K0 | |
| EMBL | AF220194 AF231037 AE014296 AE014296 AY051495 BT001795 | |
| RefSeq | NP_728573.1 NP_728574.1 | |
| UniGene | Dm.4584 | |
| ProteinModelPortal | Q9W0K0 | |
| SMR | Q9W0K0 | |
| BioGrid | 72744 | |
| DIP | DIP-20311N | |
| IntAct | Q9W0K0 | |
| MINT | MINT-839312 | |
| EnsemblMetazoa | FBtr0072627 | |
| GeneID | 53472 | |
| KEGG | dme:Dmel_CG1200 | |
| CTD | 53472 | |
| FlyBase | FBgn0040281 | |
| eggNOG | NOG266073 | |
| GeneTree | ENSGT00390000003908 | |
| InParanoid | Q9W0K0 | |
| OMA | FYSLIPN | |
| OrthoDB | EOG74J97M | |
| PhylomeDB | Q9W0K0 | |
| SignaLink | Q9W0K0 | |
| GenomeRNAi | 53472 | |
| NextBio | 841215 | |
| PRO | PR:Q9W0K0 | |
| Proteomes | UP000000803 | |
| Bgee | Q9W0K0 | |
| GO | GO:0005737 GO:0042802 GO:0019894 GO:0005078 GO:0019901 GO:0048490 GO:0019896 GO:0007254 GO:0048812 GO:0009967 GO:0046328 GO:2000331 GO:0048491 | |
| Gene3D | 2.30.29.30 | |
| InterPro | IPR011993 IPR006020 IPR001452 | |
| Pfam | PF00640 PF14604 | |
| SMART | SM00462 SM00326 | |
| SUPFAM | SSF50044 | |
| PROSITE | PS01179 PS50002 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0046328 |
regulation of JNK cascade |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0019901 |
protein kinase binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0019894 |
kinesin binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005078 |
MAP-kinase scaffold activity |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0042802 |
identical protein binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:2000331 |
regulation of terminal button organization |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0019896 |
axonal transport of mitochondrion |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0030424 |
axon |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0048490 |
anterograde synaptic vesicle transport |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0048491 |
retrograde synaptic vesicle transport |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0019894 |
kinesin binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
FB:FBgn0010235 |
F |
Seeded From UniProt |
complete | ||
|
NOT|enables |
GO:0008432 |
JUN kinase binding |
ECO:0000247 |
sequence alignment evidence used in manual assertion |
MGI:MGI:1926555 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0019901 |
protein kinase binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
FB:FBgn0010303 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0007254 |
JNK cascade |
ECO:0000247 |
sequence alignment evidence used in manual assertion |
MGI:MGI:1309464 |
P |
Seeded From UniProt |
complete | ||
|
NOT|enables |
GO:0008432 |
JUN kinase binding |
ECO:0000247 |
sequence alignment evidence used in manual assertion |
MGI:MGI:1309464 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0046328 |
regulation of JNK cascade |
ECO:0000353 |
physical interaction evidence used in manual assertion |
FB:FBgn0010303 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0007254 |
JNK cascade |
ECO:0000247 |
sequence alignment evidence used in manual assertion |
MGI:MGI:1926555 |
P |
Seeded From UniProt |
complete | ||
|
NOT|enables |
GO:0008432 |
JUN kinase binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
FB:FBgn0000229 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0019894 |
kinesin binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
FB:FBgn0010235 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0043410 |
positive regulation of MAPK cascade |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0005078 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:1904115 |
axon cytoplasm |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0019896 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0007275 |
multicellular organism development |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 Taru, H et al. (2002) Interaction of Alzheimer's beta -amyloid precursor family proteins with scaffold proteins of the JNK signaling cascade. J. Biol. Chem. 277 20070-8 PubMed GONUTS page
- ↑ Klinedinst, S et al. (2013) Independent pathways downstream of the Wnd/DLK MAPKKK regulate synaptic structure, axonal transport, and injury signaling. J. Neurosci. 33 12764-78 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 3.4 Horiuchi, D et al. (2005) APLIP1, a kinesin binding JIP-1/JNK scaffold protein, influences the axonal transport of both vesicles and mitochondria in Drosophila. Curr. Biol. 15 2137-41 PubMed GONUTS page
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