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Category:GO:0008545 ! JUN kinase kinase activity
name: JUN kinase kinase activity
namespace: molecular_function
def: "Catalysis of the phosphorylation of tyrosine and threonine residues in a c-Jun NH2-terminal kinase (JNK), a member of a subgroup of mitogen-activated protein kinases (MAPKs), which signal in response to cytokines and exposure to environmental stress. JUN kinase kinase (JNKK) is a dual-specificity protein kinase kinase and requires activation by a serine/threonine kinase JUN kinase kinase kinase." [GOC:bf, PMID:11057897, PMID:11790549]
synonym: "JNKK" EXACT []
is_a: GO:0004708 ! MAP kinase kinase activity
relationship: part_of: GO:0007254 ! JNK cascade
AmiGO
<GOterm>GO:0008545</GOterm>
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