HUMAN:RS27A

Species (Taxon ID)	Homo sapiens (Human). (9606)
Gene Name(s)	RPS27A (synonyms: UBA80, UBCEP1)
Protein Name(s)	Ubiquitin-40S ribosomal protein S27a Ubiquitin carboxyl extension protein 80 Ubiquitin 40S ribosomal protein S27a
External Links
UniProt	P62979
EMBL	X63237 S79522 AC012358 BC001392 BC066293 AB062071 M10939 AB007163
CCDS	CCDS33202.1
RefSeq	NP_001129064.1 NP_001170884.1 NP_002945.1
UniGene	Hs.311640 Hs.546292 Hs.743392
PDB	2KHW 2KOX 2KTF 2KWU 2KWV 2L0F 2L0T 2XK5 3AXC 3J3A 3K9P 3N30 3N32 3NHE 3NOB 3NS8 3PHD 3PHW 3TBL
PDBsum	2KHW 2KOX 2KTF 2KWU 2KWV 2L0F 2L0T 2XK5 3AXC 3J3A 3K9P 3N30 3N32 3NHE 3NOB 3NS8 3PHD 3PHW 3TBL
ProteinModelPortal	P62979
SMR	P62979
BioGrid	112147
IntAct	P62979
MINT	MINT-1138719
STRING	9606.ENSP00000272317
PhosphoSite	P62979
DMDM	302393745
UCD-2DPAGE	P02248
MaxQB	P62979
PaxDb	P62979
PRIDE	P62979
DNASU	6233
Ensembl	ENST00000272317 ENST00000402285 ENST00000404735
GeneID	6233
KEGG	hsa:6233
UCSC	uc002ryk.3
CTD	6233
GeneCards	GC02P055459
H-InvDB	HIX0161861
HGNC	HGNC:10417
HPA	CAB033319 HPA041344
MIM	191343
neXtProt	NX_P62979
PharmGKB	PA34821
eggNOG	COG5272
GeneTree	ENSGT00550000074763
HOVERGEN	HBG079148
InParanoid	P62979
KO	K02977
OMA	MSILKYY
OrthoDB	EOG7JDR1W
PhylomeDB	P62979
TreeFam	TF300036
Reactome	REACT_1079 REACT_11063 REACT_111080 REACT_111178 REACT_111184 REACT_1156 REACT_115662 REACT_115755 REACT_115828 REACT_115831 REACT_115852 REACT_115893 REACT_115902 REACT_1181 REACT_118614 REACT_118656 REACT_118780 REACT_120726 REACT_120727 REACT_120734 REACT_120916 REACT_121111 REACT_1221 REACT_12484 REACT_12555 REACT_13415 REACT_13464 REACT_13643 REACT_13696 REACT_1404 REACT_150471 REACT_160089 REACT_160189 REACT_160205 REACT_160243 REACT_160254 REACT_160315 REACT_1614 REACT_163977 REACT_163994 REACT_169168 REACT_169208 REACT_169325 REACT_169436 REACT_172638 REACT_1797 REACT_18265 REACT_18410 REACT_1949 REACT_1979 REACT_1986 REACT_199384 REACT_200716 REACT_200731 REACT_200766 REACT_200777 REACT_200783 REACT_200841 REACT_20549 REACT_206597 REACT_2085 REACT_21281 REACT_21368 REACT_21399 REACT_22442 REACT_228111 REACT_228209 REACT_231645 REACT_23787 REACT_24918 REACT_24941 REACT_25018 REACT_25120 REACT_25148 REACT_25271 REACT_25325 REACT_25351 REACT_25354 REACT_25359 REACT_25374 REACT_25380 REACT_267605 REACT_27258 REACT_4 REACT_6359 REACT_6761 REACT_6785 REACT_6818 REACT_6820 REACT_6821 REACT_6871 REACT_75768 REACT_75776 REACT_75822 REACT_75842 REACT_79 REACT_821 REACT_9003 REACT_9031 REACT_931 REACT_9453 REACT_9491
ChiTaRS	RPS27A
EvolutionaryTrace	P62979
GeneWiki	RPS27A
GenomeRNAi	6233
NextBio	24197
PRO	PR:P62979
Proteomes	UP000005640
Bgee	P62979
CleanEx	HS_RPS27A
ExpressionAtlas	P62979
Genevestigator	P62979
GO	GO:0005829 GO:0022627 GO:0030666 GO:0010008 GO:0070062 GO:0016020 GO:0005654 GO:0005886 GO:0015935 GO:0046872 GO:0044822 GO:0003735 GO:0000187 GO:0031145 GO:0042590 GO:0002479 GO:0002474 GO:0006915 GO:0097190 GO:0005975 GO:0044267 GO:0071456 GO:0019221 GO:0006977 GO:0006281 GO:0016197 GO:0007173 GO:0038095 GO:0008543 GO:0000082 GO:0000086 GO:0010467 GO:0006006 GO:0005978 GO:0007249 GO:0045087 GO:0075733 GO:0034220 GO:0007254 GO:0061024 GO:0000278 GO:0016071 GO:0002755 GO:0002756 GO:0043066 GO:0042059 GO:0000122 GO:0030512 GO:0032480 GO:0051436 GO:0048011 GO:0007220 GO:0007219 GO:0000184 GO:0035872 GO:0070423 GO:0043065 GO:0043123 GO:0051092 GO:0045944 GO:0032481 GO:0051437 GO:0000209 GO:0042981 GO:0061418 GO:0032479 GO:0051439 GO:0016070 GO:0044281 GO:0006614 GO:0051403 GO:0050852 GO:0034166 GO:0034134 GO:0034138 GO:0034142 GO:0034146 GO:0034162 GO:0002224 GO:0038123 GO:0038124 GO:0006367 GO:0006351 GO:0007179 GO:0006412 GO:0006414 GO:0006413 GO:0006415 GO:0055085 GO:0035666 GO:0019058 GO:0016032 GO:0019082 GO:0019083 GO:0019068
InterPro	IPR002906 IPR011332 IPR019956 IPR000626 IPR029071 IPR019954
Pfam	PF01599 PF00240
PRINTS	PR00348
SMART	SM00213
SUPFAM	SSF54236 SSF57829
PROSITE	PS00299 PS50053

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0022627	cytosolic small ribosomal subunit	PMID:15883184^[1]	ECO:0000314			C		Mass spec. analysis of the small ribosomal subunit showed that this protein was involved in the small subunit.	complete
part_of	GO:0031982	vesicle	PMID:19190083^[2]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:21630459^[3]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C	part_of:(CL:0000019)	Seeded From UniProt	complete
part_of	GO:0005615	extracellular space	PMID:16502470^[4]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C	part_of:(UBERON:0001914)	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	PMID:16791210^[5]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005730	nucleolus	PMID:16791210^[5]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0070062	extracellular exosome	PMID:23533145^[6]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0016020	membrane	PMID:19946888^[7]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0070062	extracellular exosome	PMID:19199708^[8]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C	part_of:(UBERON:0001831)	Seeded From UniProt	complete
part_of	GO:0070062	extracellular exosome	PMID:20458337^[9]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C	part_of:(CL:0000639)	Seeded From UniProt	complete
enables	GO:0003723	RNA binding	PMID:22681889^[10]	ECO:0007005	high throughput direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0003723	RNA binding	PMID:22658674^[11]	ECO:0007005	high throughput direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
part_of	GO:0022627	cytosolic small ribosomal subunit	PMID:8706699^[12]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0022627	cytosolic small ribosomal subunit	PMID:15883184^[1]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0015935	small ribosomal subunit	PMID:15883184^[1]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0006412	translation	PMID:8706699^[12]	ECO:0000305	curator inference used in manual assertion	GO:0022627	P		Seeded From UniProt	complete
involved_in	GO:0006412	translation	PMID:15883184^[1]	ECO:0000305	curator inference used in manual assertion	GO:0015935	P		Seeded From UniProt	complete
enables	GO:0003735	structural constituent of ribosome	PMID:15883184^[1]	ECO:0007005	high throughput direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0031625	ubiquitin protein ligase binding	PMID:21873635^[13]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000071508 UniProtKB:Q15843	F		Seeded From UniProt	complete
enables	GO:0031386	protein tag	PMID:21873635^[13]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1855694 PANTHER:PTN000071508 PomBase:SPBC12D12.08c SGD:S000002546 SGD:S000004157 UniProtKB:A0A1D8PJP6	F		Seeded From UniProt	complete
part_of	GO:0022627	cytosolic small ribosomal subunit	PMID:21873635^[13]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN002241455 RGD:6489478 UniProtKB:P62979	C		Seeded From UniProt	complete
involved_in	GO:0019941	modification-dependent protein catabolic process	PMID:21873635^[13]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1855694 PANTHER:PTN000071508	P		Seeded From UniProt	complete
involved_in	GO:0016567	protein ubiquitination	PMID:21873635^[13]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000071508 SGD:S000001410 SGD:S000001802 UniProtKB:Q5A109	P		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	PMID:21873635^[13]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000071508 RGD:68344 WB:WBGene00003587	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:21873635^[13]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:97301 PANTHER:PTN000071508 RGD:3158 RGD:68344 WB:WBGene00003587	C		Seeded From UniProt	complete
part_of	GO:0043657	host cell	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0075733	C		Seeded From UniProt	complete
enables	GO:0003735	structural constituent of ribosome	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002906	F		Seeded From UniProt	complete
part_of	GO:0005840	ribosome	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002906	C		Seeded From UniProt	complete
involved_in	GO:0006412	translation	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002906 InterPro:IPR011332	P		Seeded From UniProt	complete
involved_in	GO:0075733	intracellular transport of virus	Reactome:R-HSA-174490	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0070987	error-free translesion synthesis	Reactome:R-HSA-110320	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0070911	global genome nucleotide-excision repair	Reactome:R-HSA-5696399	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0070498	interleukin-1-mediated signaling pathway	Reactome:R-HSA-9020702	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0070423	nucleotide-binding oligomerization domain containing signaling pathway	Reactome:R-HSA-168638	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia	Reactome:R-HSA-1234174	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0061024	membrane organization	Reactome:R-HSA-199991	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0055085	transmembrane transport	Reactome:R-HSA-382556	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0051403	stress-activated MAPK cascade	Reactome:R-HSA-450294	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0051092	positive regulation of NF-kappaB transcription factor activity	Reactome:R-HSA-445989	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045944	positive regulation of transcription by RNA polymerase II	Reactome:R-HSA-2173796	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0044267	cellular protein metabolic process	Reactome:R-HSA-392499	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0043488	regulation of mRNA stability	Reactome:R-HSA-450408	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0043066	negative regulation of apoptotic process	Reactome:R-HSA-193639	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0043065	positive regulation of apoptotic process	Reactome:R-HSA-205043	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0042769	DNA damage response, detection of DNA damage	Reactome:R-HSA-110314	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0042276	error-prone translesion synthesis	Reactome:R-HSA-5656121 Reactome:R-HSA-5655862 Reactome:R-HSA-110312	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0036297	interstrand cross-link repair	Reactome:R-HSA-6783310	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0035666	TRIF-dependent toll-like receptor signaling pathway	Reactome:R-HSA-937061 Reactome:R-HSA-936964 Reactome:R-HSA-9013973	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0033683	nucleotide-excision repair, DNA incision	Reactome:R-HSA-5696400	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0031145	anaphase-promoting complex-dependent catabolic process	Reactome:R-HSA-174048	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0030666	endocytic vesicle membrane	Reactome:R-HSA-917693	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	Reactome:R-HSA-2173788	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0019985	translesion synthesis	Reactome:R-HSA-110313	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0019221	cytokine-mediated signaling pathway	Reactome:R-HSA-512988	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0019083	viral transcription	Reactome:R-HSA-168273	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0019068	virion assembly	Reactome:R-HSA-175474	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0019058	viral life cycle	Reactome:R-HSA-162588	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0016579	protein deubiquitination	Reactome:R-HSA-5688426	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0016567	protein ubiquitination	Reactome:R-HSA-8866654 Reactome:R-HSA-8866652	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0016197	endosomal transport	Reactome:R-HSA-917729	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0016055	Wnt signaling pathway	Reactome:R-HSA-195721	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0010008	endosome membrane	Reactome:R-HSA-917730 Reactome:R-HSA-917700 Reactome:R-HSA-917696 Reactome:R-HSA-917693 Reactome:R-HSA-847070 Reactome:R-HSA-3149434 Reactome:R-HSA-184269 Reactome:R-HSA-177692 Reactome:R-HSA-177690	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0007254	JNK cascade	Reactome:R-HSA-450321	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0007249	I-kappaB kinase/NF-kappaB signaling	Reactome:R-HSA-937072 Reactome:R-HSA-9014325	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0007179	transforming growth factor beta receptor signaling pathway	Reactome:R-HSA-2173791	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006625	protein targeting to peroxisome	Reactome:R-HSA-9033241	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006614	SRP-dependent cotranslational protein targeting to membrane	Reactome:R-HSA-1799339	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006413	translational initiation	Reactome:R-HSA-72613	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006297	nucleotide-excision repair, DNA gap filling	Reactome:R-HSA-5696397	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006296	nucleotide-excision repair, DNA incision, 5'-to lesion	Reactome:R-HSA-5690988	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006294	nucleotide-excision repair, preincision complex assembly	Reactome:R-HSA-5691000 Reactome:R-HSA-5689861	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006283	transcription-coupled nucleotide-excision repair	Reactome:R-HSA-6781827	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	Reactome:R-HSA-3159227 Reactome:R-HSA-3149454 Reactome:R-HSA-3149434 Reactome:R-HSA-3139027	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005829	cytosol	Reactome:R-NUL-9011324 Reactome:R-NUL-9011317 Reactome:R-NUL-5610711 Reactome:R-NUL-2179313 Reactome:R-NUL-2179307 Reactome:R-NUL-2176427 Reactome:R-NUL-2176396 Reactome:R-NUL-2176393 Reactome:R-NUL-212920 Reactome:R-NUL-212917 Reactome:R-NUL-209162 Reactome:R-NUL-2071858 Reactome:R-HSA-990526 Reactome:R-HSA-983157 Reactome:R-HSA-983156 Reactome:R-HSA-983153 Reactome:R-HSA-983152 Reactome:R-HSA-983150 Reactome:R-HSA-983140 Reactome:R-HSA-975147 Reactome:R-HSA-975122 Reactome:R-HSA-975118 Reactome:R-HSA-975103 Reactome:R-HSA-975097 Reactome:R-HSA-9628444 Reactome:R-HSA-937075 Reactome:R-HSA-937050 Reactome:R-HSA-936991 Reactome:R-HSA-936986 Reactome:R-HSA-936960 Reactome:R-HSA-936952 Reactome:R-HSA-936951 Reactome:R-HSA-936947 Reactome:R-HSA-936942 Reactome:R-HSA-936475 Reactome:R-HSA-936390 Reactome:R-HSA-936381 Reactome:R-HSA-934604 Reactome:R-HSA-927889 Reactome:R-HSA-927836 Reactome:R-HSA-927832 Reactome:R-HSA-927813 Reactome:R-HSA-927789 Reactome:R-HSA-918224 Reactome:R-HSA-912627 Reactome:R-HSA-9033533 Reactome:R-HSA-9033527 Reactome:R-HSA-9033516 Reactome:R-HSA-9033509 Reactome:R-HSA-9033499 Reactome:R-HSA-9033491 Reactome:R-HSA-9033485 Reactome:R-HSA-9021523 Reactome:R-HSA-9014342 Reactome:R-HSA-9013990 Reactome:R-HSA-9013974 Reactome:R-HSA-9009308 Reactome:R-HSA-8986083 Reactome:R-HSA-8957265 Reactome:R-HSA-8956684 Reactome:R-HSA-8956106 Reactome:R-HSA-8956026 Reactome:R-HSA-8953946 Reactome:R-HSA-8953917 Reactome:R-HSA-8952408 Reactome:R-HSA-8948832 Reactome:R-HSA-8948775 Reactome:R-HSA-8948709 Reactome:R-HSA-8948063 Reactome:R-HSA-8948015 Reactome:R-HSA-8939335 Reactome:R-HSA-8939323 Reactome:R-HSA-8938829 Reactome:R-HSA-8938815 Reactome:R-HSA-8938773 Reactome:R-HSA-8938770 Reactome:R-HSA-8877003 Reactome:R-HSA-8876258 Reactome:R-HSA-8875443 Reactome:R-HSA-8875431 Reactome:R-HSA-8875183 Reactome:R-HSA-8871194 Reactome:R-HSA-8871193 Reactome:R-HSA-8869506 Reactome:R-HSA-8869456 Reactome:R-HSA-8869438 Reactome:R-HSA-8868661 Reactome:R-HSA-8868660 Reactome:R-HSA-8868659 Reactome:R-HSA-8868658 Reactome:R-HSA-8868651 Reactome:R-HSA-8868648 Reactome:R-HSA-8868236 Reactome:R-HSA-8868230 Reactome:R-HSA-8868072 Reactome:R-HSA-8868071 Reactome:R-HSA-8867756 Reactome:R-HSA-8867754 Reactome:R-HSA-8867288 Reactome:R-HSA-8866858 Reactome:R-HSA-8866856 Reactome:R-HSA-8866854 Reactome:R-HSA-8866553 Reactome:R-HSA-8866546 Reactome:R-HSA-8866542 Reactome:R-HSA-8866279 Reactome:R-HSA-8865182 Reactome:R-HSA-8854071 Reactome:R-HSA-8854051 Reactome:R-HSA-8854044 Reactome:R-HSA-8854041 Reactome:R-HSA-8853503 Reactome:R-HSA-8853379 Reactome:R-HSA-8852354 Reactome:R-HSA-8852134 Reactome:R-HSA-8852133 Reactome:R-HSA-8852132 Reactome:R-HSA-8852129 Reactome:R-HSA-8852127 Reactome:R-HSA-8851011 Reactome:R-HSA-8850992 Reactome:R-HSA-8850594 Reactome:R-HSA-8848829 Reactome:R-HSA-870479 Reactome:R-HSA-870477 Reactome:R-HSA-870437 Reactome:R-HSA-847070 Reactome:R-HSA-75825 Reactome:R-HSA-75824 Reactome:R-HSA-741411 Reactome:R-HSA-741386 Reactome:R-HSA-72697 Reactome:R-HSA-72691 Reactome:R-HSA-72676 Reactome:R-HSA-72673 Reactome:R-HSA-72672 Reactome:R-HSA-72671 Reactome:R-HSA-72621 Reactome:R-HSA-72619 Reactome:R-HSA-706479 Reactome:R-HSA-69600 Reactome:R-HSA-69598 Reactome:R-HSA-69016 Reactome:R-HSA-69015 Reactome:R-HSA-68948 Reactome:R-HSA-688985 Reactome:R-HSA-68825 Reactome:R-HSA-688137 Reactome:R-HSA-688136 Reactome:R-HSA-68712 Reactome:R-HSA-6807206 Reactome:R-HSA-6807134 Reactome:R-HSA-6807106 Reactome:R-HSA-6791223 Reactome:R-HSA-6782628 Reactome:R-HSA-6782106 Reactome:R-HSA-6781897 Reactome:R-HSA-6781814 Reactome:R-HSA-6781779 Reactome:R-HSA-6781764 Reactome:R-HSA-5696968 Reactome:R-HSA-5696945 Reactome:R-HSA-5696627 Reactome:R-HSA-5696600 Reactome:R-HSA-5696564 Reactome:R-HSA-5696547 Reactome:R-HSA-5696534 Reactome:R-HSA-5693108 Reactome:R-HSA-5691439 Reactome:R-HSA-5691431 Reactome:R-HSA-5691108 Reactome:R-HSA-5690870 Reactome:R-HSA-5690856 Reactome:R-HSA-5690827 Reactome:R-HSA-5690319 Reactome:R-HSA-5690196 Reactome:R-HSA-5690159 Reactome:R-HSA-5690152 Reactome:R-HSA-5689111 Reactome:R-HSA-5688837 Reactome:R-HSA-5688797 Reactome:R-HSA-5687112 Reactome:R-HSA-5687081 Reactome:R-HSA-5684273 Reactome:R-HSA-5684250 Reactome:R-HSA-5675470 Reactome:R-HSA-5674022 Reactome:R-HSA-5668534 Reactome:R-HSA-5668454 Reactome:R-HSA-5668414 Reactome:R-HSA-5667111 Reactome:R-HSA-5667107 Reactome:R-HSA-5660753 Reactome:R-HSA-5660752 Reactome:R-HSA-5658496 Reactome:R-HSA-5658424 Reactome:R-HSA-5654684 Reactome:R-HSA-5654679 Reactome:R-HSA-5654677 Reactome:R-HSA-5654672 Reactome:R-HSA-5635868 Reactome:R-HSA-5635864 Reactome:R-HSA-5610746 Reactome:R-HSA-5610742 Reactome:R-HSA-5607757 Reactome:R-HSA-5607756 Reactome:R-HSA-5607731 Reactome:R-HSA-5607728 Reactome:R-HSA-5607725 Reactome:R-HSA-5483238 Reactome:R-HSA-5387392 Reactome:R-HSA-5362500 Reactome:R-HSA-5362448 Reactome:R-HSA-5362412 Reactome:R-HSA-5357845 Reactome:R-HSA-5357757 Reactome:R-HSA-5246693 Reactome:R-HSA-5205682 Reactome:R-HSA-4641260 Reactome:R-HSA-4641256 Reactome:R-HSA-4641253 Reactome:R-HSA-4641246 Reactome:R-HSA-4641236 Reactome:R-HSA-4641159 Reactome:R-HSA-4641129 Reactome:R-HSA-4608852 Reactome:R-HSA-451418 Reactome:R-HSA-450580 Reactome:R-HSA-450358 Reactome:R-HSA-450346 Reactome:R-HSA-450337 Reactome:R-HSA-450259 Reactome:R-HSA-446877 Reactome:R-HSA-3797226 Reactome:R-HSA-3781009 Reactome:R-HSA-3780995 Reactome:R-HSA-3640874 Reactome:R-HSA-3640872 Reactome:R-HSA-3640861 Reactome:R-HSA-3249386 Reactome:R-HSA-3134946 Reactome:R-HSA-3134804 Reactome:R-HSA-3000335 Reactome:R-HSA-2900765 Reactome:R-HSA-2769007 Reactome:R-HSA-2737728 Reactome:R-HSA-2730904 Reactome:R-HSA-2730752 Reactome:R-HSA-2682349 Reactome:R-HSA-264458 Reactome:R-HSA-264444 Reactome:R-HSA-2220976 Reactome:R-HSA-2220944 Reactome:R-HSA-2213017 Reactome:R-HSA-2187382 Reactome:R-HSA-2187368 Reactome:R-HSA-2176452 Reactome:R-HSA-2169046 Reactome:R-HSA-2160935 Reactome:R-HSA-2160931 Reactome:R-HSA-2130286 Reactome:R-HSA-2130282 Reactome:R-HSA-209566 Reactome:R-HSA-209536 Reactome:R-HSA-209063 Reactome:R-HSA-209061 Reactome:R-HSA-205118 Reactome:R-HSA-205008 Reactome:R-HSA-204947 Reactome:R-HSA-202534 Reactome:R-HSA-202453 Reactome:R-HSA-1977296 Reactome:R-HSA-192841 Reactome:R-HSA-192704 Reactome:R-HSA-1918095 Reactome:R-HSA-1918092 Reactome:R-HSA-1912357 Reactome:R-HSA-188191 Reactome:R-HSA-184323 Reactome:R-HSA-184269 Reactome:R-HSA-183089 Reactome:R-HSA-183084 Reactome:R-HSA-183051 Reactome:R-HSA-183036 Reactome:R-HSA-182993 Reactome:R-HSA-182986 Reactome:R-HSA-180603 Reactome:R-HSA-180597 Reactome:R-HSA-180573 Reactome:R-HSA-180540 Reactome:R-HSA-1799335 Reactome:R-HSA-1799332 Reactome:R-HSA-179421 Reactome:R-HSA-179417 Reactome:R-HSA-177690 Reactome:R-HSA-174255 Reactome:R-HSA-174227 Reactome:R-HSA-174203 Reactome:R-HSA-174202 Reactome:R-HSA-174195 Reactome:R-HSA-174159 Reactome:R-HSA-174157 Reactome:R-HSA-174144 Reactome:R-HSA-174105 Reactome:R-HSA-174104 Reactome:R-HSA-173542 Reactome:R-HSA-168915 Reactome:R-HSA-168184 Reactome:R-HSA-157849 Reactome:R-HSA-156823 Reactome:R-HSA-156808 Reactome:R-HSA-1504193 Reactome:R-HSA-1504190 Reactome:R-HSA-1358797 Reactome:R-HSA-1358795 Reactome:R-HSA-1358792 Reactome:R-HSA-1358790 Reactome:R-HSA-1358789 Reactome:R-HSA-1295621 Reactome:R-HSA-1253282 Reactome:R-HSA-1234175 Reactome:R-HSA-1234163 Reactome:R-HSA-1234159 Reactome:R-HSA-1225956 Reactome:R-HSA-1169307 Reactome:R-HSA-1168643 Reactome:R-HSA-1022127	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005789	endoplasmic reticulum membrane	Reactome:R-HSA-8943083 Reactome:R-HSA-8943080	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005741	mitochondrial outer membrane	Reactome:R-HSA-5696872	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	Reactome:R-NUL-2186775 Reactome:R-NUL-2186755 Reactome:R-NUL-2064883 Reactome:R-HSA-8952419 Reactome:R-HSA-8952382 Reactome:R-HSA-8943041 Reactome:R-HSA-8943040 Reactome:R-HSA-8943007 Reactome:R-HSA-8943003 Reactome:R-HSA-8942101 Reactome:R-HSA-8942099 Reactome:R-HSA-8939801 Reactome:R-HSA-8939706 Reactome:R-HSA-8862184 Reactome:R-HSA-8852136 Reactome:R-HSA-8852131 Reactome:R-HSA-8852130 Reactome:R-HSA-8852128 Reactome:R-HSA-870477 Reactome:R-HSA-870449 Reactome:R-HSA-68946 Reactome:R-HSA-6807118 Reactome:R-HSA-6804942 Reactome:R-HSA-6804879 Reactome:R-HSA-6804724 Reactome:R-HSA-6804441 Reactome:R-HSA-6804253 Reactome:R-HSA-6798373 Reactome:R-HSA-6791223 Reactome:R-HSA-6790487 Reactome:R-HSA-6790454 Reactome:R-HSA-6786171 Reactome:R-HSA-6786166 Reactome:R-HSA-6786155 Reactome:R-HSA-6785986 Reactome:R-HSA-6785732 Reactome:R-HSA-6785361 Reactome:R-HSA-6783177 Reactome:R-HSA-6782943 Reactome:R-HSA-6782820 Reactome:R-HSA-6782234 Reactome:R-HSA-6782227 Reactome:R-HSA-6782224 Reactome:R-HSA-6782211 Reactome:R-HSA-6782208 Reactome:R-HSA-6782204 Reactome:R-HSA-6782141 Reactome:R-HSA-6782138 Reactome:R-HSA-6782131 Reactome:R-HSA-6782069 Reactome:R-HSA-6782004 Reactome:R-HSA-6781867 Reactome:R-HSA-5697009 Reactome:R-HSA-5696997 Reactome:R-HSA-5696960 Reactome:R-HSA-5696958 Reactome:R-HSA-5696947 Reactome:R-HSA-5696914 Reactome:R-HSA-5696670 Reactome:R-HSA-5696664 Reactome:R-HSA-5696655 Reactome:R-HSA-5696605 Reactome:R-HSA-5696465 Reactome:R-HSA-5691411 Reactome:R-HSA-5691381 Reactome:R-HSA-5691001 Reactome:R-HSA-5691000 Reactome:R-HSA-5690997 Reactome:R-HSA-5690996 Reactome:R-HSA-5690988 Reactome:R-HSA-5690790 Reactome:R-HSA-5690759 Reactome:R-HSA-5690213 Reactome:R-HSA-5690157 Reactome:R-HSA-5690080 Reactome:R-HSA-5689973 Reactome:R-HSA-5689972 Reactome:R-HSA-5689950 Reactome:R-HSA-5689861 Reactome:R-HSA-5684071 Reactome:R-HSA-5683077 Reactome:R-HSA-5682858 Reactome:R-HSA-5656158 Reactome:R-HSA-5656148 Reactome:R-HSA-5656105 Reactome:R-HSA-5655965 Reactome:R-HSA-5655892 Reactome:R-HSA-5655835 Reactome:R-HSA-5655481 Reactome:R-HSA-5655466 Reactome:R-HSA-5655193 Reactome:R-HSA-5655170 Reactome:R-HSA-5654989 Reactome:R-HSA-5654986 Reactome:R-HSA-5654985 Reactome:R-HSA-5653770 Reactome:R-HSA-5653766 Reactome:R-HSA-5653756 Reactome:R-HSA-5653754 Reactome:R-HSA-5652151 Reactome:R-HSA-5652009 Reactome:R-HSA-5635856 Reactome:R-HSA-5635854 Reactome:R-HSA-3788724 Reactome:R-HSA-3322429 Reactome:R-HSA-3215310 Reactome:R-HSA-3215295 Reactome:R-HSA-2186780 Reactome:R-HSA-2186767 Reactome:R-HSA-2179276 Reactome:R-HSA-2176503 Reactome:R-HSA-2176502 Reactome:R-HSA-204947 Reactome:R-HSA-187575 Reactome:R-HSA-187574 Reactome:R-HSA-174058 Reactome:R-HSA-174057 Reactome:R-HSA-1363331 Reactome:R-HSA-1234175 Reactome:R-HSA-1234172 Reactome:R-HSA-110319 Reactome:R-HSA-110317 Reactome:R-HSA-110316 Reactome:R-HSA-110311 Reactome:R-HSA-110308 Reactome:R-HSA-110307	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0002756	MyD88-independent toll-like receptor signaling pathway	Reactome:R-HSA-168927	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0002755	MyD88-dependent toll-like receptor signaling pathway	Reactome:R-HSA-975871 Reactome:R-HSA-166058	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0000717	nucleotide-excision repair, DNA duplex unwinding	Reactome:R-HSA-5690996	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0000715	nucleotide-excision repair, DNA damage recognition	Reactome:R-HSA-5696394	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0000209	protein polyubiquitination	Reactome:R-HSA-983168	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0000187	activation of MAPK activity	Reactome:R-HSA-450302	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	Reactome:R-HSA-927802	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0000122	negative regulation of transcription by RNA polymerase II	Reactome:R-HSA-2173795	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005840	ribosome	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0689	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C		Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F		Seeded From UniProt	complete
edit table

Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 Yu, Y et al. (2005) Mass spectrometric analysis of the human 40S ribosomal subunit: native and HCV IRES-bound complexes. Protein Sci. 14 1438-46 PubMed GONUTS page
↑ Kesimer, M et al. (2009) Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense. FASEB J. 23 1858-68 PubMed GONUTS page
↑ de Mateo, S et al. (2011) Proteomic characterization of the human sperm nucleus. Proteomics 11 2714-26 PubMed GONUTS page
↑ Palmer, DJ et al. (2006) Human colostrum: identification of minor proteins in the aqueous phase by proteomics. Proteomics 6 2208-16 PubMed GONUTS page
↑ ^5.0 ^5.1 Sigal, A et al. (2006) Dynamic proteomics in individual human cells uncovers widespread cell-cycle dependence of nuclear proteins. Nat. Methods 3 525-31 PubMed GONUTS page
↑ Principe, S et al. (2013) In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. Proteomics 13 1667-71 PubMed GONUTS page
↑ Ghosh, D et al. (2010) Defining the membrane proteome of NK cells. J Mass Spectrom 45 1-25 PubMed GONUTS page
↑ Gonzalez-Begne, M et al. (2009) Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT). J. Proteome Res. 8 1304-14 PubMed GONUTS page
↑ Buschow, SI et al. () MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis. Immunol. Cell Biol. 88 851-6 PubMed GONUTS page
↑ Baltz, AG et al. (2012) The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. Mol. Cell 46 674-90 PubMed GONUTS page
↑ Castello, A et al. (2012) Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. Cell 149 1393-406 PubMed GONUTS page
↑ ^12.0 ^12.1 Vladimirov, SN et al. (1996) Characterization of the human small-ribosomal-subunit proteins by N-terminal and internal sequencing, and mass spectrometry. Eur. J. Biochem. 239 144-9 PubMed GONUTS page
↑ ^13.0 ^13.1 ^13.2 ^13.3 ^13.4 ^13.5 ^13.6 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:15883184-1] 1.0 ^1.1 ^1.2 ^1.3 ^1.4 Yu, Y et al. (2005) Mass spectrometric analysis of the human 40S ribosomal subunit: native and HCV IRES-bound complexes. Protein Sci. 14 1438-46 PubMed GONUTS page

[PMID:19190083-2] Kesimer, M et al. (2009) Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense. FASEB J. 23 1858-68 PubMed GONUTS page

[PMID:21630459-3] Mateo, S et al. (2011) Proteomic characterization of the human sperm nucleus. Proteomics 11 2714-26 PubMed GONUTS page

[PMID:16502470-4] Palmer, DJ et al. (2006) Human colostrum: identification of minor proteins in the aqueous phase by proteomics. Proteomics 6 2208-16 PubMed GONUTS page

[PMID:16791210-5] 5.0 ^5.1 Sigal, A et al. (2006) Dynamic proteomics in individual human cells uncovers widespread cell-cycle dependence of nuclear proteins. Nat. Methods 3 525-31 PubMed GONUTS page

[PMID:23533145-6] Principe, S et al. (2013) In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine. Proteomics 13 1667-71 PubMed GONUTS page

[PMID:19946888-7] Ghosh, D et al. (2010) Defining the membrane proteome of NK cells. J Mass Spectrom 45 1-25 PubMed GONUTS page

[PMID:19199708-8] Gonzalez-Begne, M et al. (2009) Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT). J. Proteome Res. 8 1304-14 PubMed GONUTS page

[PMID:20458337-9] Buschow, SI et al. () MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis. Immunol. Cell Biol. 88 851-6 PubMed GONUTS page

[PMID:22681889-10] Baltz, AG et al. (2012) The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. Mol. Cell 46 674-90 PubMed GONUTS page

[PMID:22658674-11] Castello, A et al. (2012) Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. Cell 149 1393-406 PubMed GONUTS page

[PMID:8706699-12] 12.0 ^12.1 Vladimirov, SN et al. (1996) Characterization of the human small-ribosomal-subunit proteins by N-terminal and internal sequencing, and mass spectrometry. Eur. J. Biochem. 239 144-9 PubMed GONUTS page

[PMID:21873635-13] 13.0 ^13.1 ^13.2 ^13.3 ^13.4 ^13.5 ^13.6 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[1]

[2]

[3]

[4]

[5]

[6]

[7]

[8]

[9]

[10]

[11]

[12]

[13]

HUMAN:RS27A

Contents

Annotations

Notes

References

a

c

e

g

h

i

j

m

n

o

p

r

s

t

u

v

w

Navigation menu

Personal tools

Namespaces

Variants

Views

More

Search

Navigation

Cacao

Links

Tools