name: translesion synthesis
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def: "The replication of damaged DNA by synthesis across a lesion in the template strand; a specialized DNA polymerase or replication complex inserts a defined nucleotide across from the lesion which allows DNA synthesis to continue beyond the lesion. This process can be mutagenic depending on the damaged nucleotide and the inserted nucleotide." [GOC:elh, GOC:vw, PMID:10535901]
synonym: "bypass DNA synthesis" EXACT [GOC:elh]
is_a: GO:0000731 ! DNA synthesis involved in DNA repair
is_a: GO:0006301 ! postreplication repair
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Pages in category "GO:0019985 ! translesion synthesis"
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