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CHICK:MD2L2
Contents
| Species (Taxon ID) | Gallus gallus (Chicken). (9031) | |
| Gene Name(s) | MAD2L2 (synonyms: REV7) | |
| Protein Name(s) | Mitotic spindle assembly checkpoint protein MAD2B
Mitotic arrest deficient 2-like protein 2 MAD2-like protein 2 | |
| External Links | ||
| UniProt | Q4KWZ6 | |
| EMBL | AY675170 | |
| RefSeq | NP_001020749.1 | |
| UniGene | Gga.7853 | |
| ProteinModelPortal | Q4KWZ6 | |
| STRING | 9031.ENSGALP00000007380 | |
| Ensembl | ENSGALT00000007392 | |
| GeneID | 419493 | |
| KEGG | gga:419493 | |
| CTD | 10459 | |
| eggNOG | NOG292947 | |
| GeneTree | ENSGT00500000044946 | |
| HOGENOM | HOG000231083 | |
| HOVERGEN | HBG052443 | |
| InParanoid | Q4KWZ6 | |
| KO | K13728 | |
| OMA | NNNPPGC | |
| OrthoDB | EOG7SN8FC | |
| PhylomeDB | Q4KWZ6 | |
| TreeFam | TF101085 | |
| Reactome | REACT_116049 REACT_116052 REACT_229980 | |
| NextBio | 20822541 | |
| PRO | PR:Q4KWZ6 | |
| Proteomes | UP000000539 | |
| GO | GO:0005680 GO:0005737 GO:0005654 GO:0005634 GO:0005819 GO:0016035 GO:0017125 GO:0007015 GO:0042772 GO:0006281 GO:0000724 GO:0042276 GO:0007067 GO:0090090 GO:2000048 GO:0010719 GO:0060564 GO:0042177 GO:0043433 GO:0010944 GO:0000122 GO:2000678 GO:0033138 GO:0045893 GO:0001558 GO:0009411 GO:0006351 GO:0019985 | |
| Gene3D | 3.30.900.10 | |
| InterPro | IPR003511 | |
| Pfam | PF02301 | |
| SUPFAM | SSF56019 | |
| PROSITE | PS50815 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0042276 |
error-prone translesion synthesis |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0017125 |
deoxycytidyl transferase activity |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009411 |
response to UV |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:1904667 |
negative regulation of ubiquitin protein ligase activity |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0045893 |
positive regulation of transcription, DNA-templated |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0042772 |
DNA damage response, signal transduction resulting in transcription |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0042177 |
negative regulation of protein catabolic process |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0033138 |
positive regulation of peptidyl-serine phosphorylation |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016035 |
zeta DNA polymerase complex |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006281 |
DNA repair |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005819 |
spindle |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
colocalizes_with |
GO:0005680 |
anaphase-promoting complex |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0001558 |
regulation of cell growth |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0000724 |
double-strand break repair via homologous recombination |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
NOT|involved_in |
GO:0000077 |
DNA damage checkpoint |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0019985 |
translesion synthesis |
Reactome:R-GGA-353473 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
|
P |
Seeded From UniProt |
complete | |
|
part_of |
GO:0005654 |
nucleoplasm |
Reactome:R-GGA-353434 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
|
C |
Seeded From UniProt |
complete | |
|
involved_in |
GO:0006974 |
cellular response to DNA damage stimulus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0051301 |
cell division |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006281 |
DNA repair |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007049 |
cell cycle |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005694 |
chromosome |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005856 |
cytoskeleton |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005819 |
spindle |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Hara, K et al. (2010) Crystal structure of human REV7 in complex with a human REV3 fragment and structural implication of the interaction between DNA polymerase zeta and REV1. J. Biol. Chem. 285 12299-307 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Okada, T et al. (2005) Multiple roles of vertebrate REV genes in DNA repair and recombination. Mol. Cell. Biol. 25 6103-11 PubMed GONUTS page
c
d
- GO:0017125 ! deoxycytidyl transferase activity
- Dinosauria
- GO:0000077 ! DNA damage checkpoint signaling
- GO:0042772 ! DNA damage response, signal transduction resulting in transcription
- GO:0006974 ! DNA damage response
- GO:0006281 ! DNA repair
- GO:0000724 ! double-strand break repair via homologous recombination
m
n
p
