MOUSE:POLK

Species (Taxon ID)	Mus musculus (Mouse). (10090)
Gene Name(s)	Polk (synonyms: Dinb1)
Protein Name(s)	DNA polymerase kappa DINB protein DINP
External Links
UniProt	Q9QUG2
EMBL	AB027563 AF163571 AB040765 BC052820
CCDS	CCDS26704.1
RefSeq	NP_036178.1
UniGene	Mm.89926
PDB	2LSJ 4FJO
PDBsum	2LSJ 4FJO
ProteinModelPortal	Q9QUG2
SMR	Q9QUG2
BioGrid	205098
IntAct	Q9QUG2
STRING	10090.ENSMUSP00000022172
PhosphoSite	Q9QUG2
MaxQB	Q9QUG2
PaxDb	Q9QUG2
PRIDE	Q9QUG2
Ensembl	ENSMUST00000022172
GeneID	27015
KEGG	mmu:27015
UCSC	uc007rne.1
CTD	51426
MGI	MGI:1349767
eggNOG	COG0389
GeneTree	ENSGT00530000062942
HOGENOM	HOG000082711
HOVERGEN	HBG101212
InParanoid	Q9QUG2
KO	K03511
OMA	NWPEDKR
OrthoDB	EOG73Z2SP
PhylomeDB	Q9QUG2
TreeFam	TF314387
NextBio	304949
PRO	PR:Q9QUG2
Proteomes	UP000000589
Bgee	Q9QUG2
CleanEx	MM_POLK
ExpressionAtlas	Q9QUG2
Genevestigator	Q9QUG2
GO	GO:0005634 GO:0003684 GO:0003887 GO:0046872 GO:0006281 GO:0006260 GO:0006297
Gene3D	3.30.1490.100
HAMAP	MF_01113
InterPro	IPR017961 IPR001126 IPR017963 IPR022880 IPR006642
Pfam	PF00817 PF11799
SMART	SM00734
SUPFAM	SSF100879
PROSITE	PS50173

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
colocalizes_with	GO:0090734	site of DNA damage	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9UBT6	C	Seeded From UniProt	complete
involved_in	GO:0042276	error-prone translesion synthesis	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9UBT6	P	Seeded From UniProt	complete
involved_in	GO:0034644	cellular response to UV	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9UBT6	P	Seeded From UniProt	complete
involved_in	GO:0006974	cellular response to DNA damage stimulus	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9UBT6	P	Seeded From UniProt	complete
involved_in	GO:0006281	DNA repair	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9UBT6	P	Seeded From UniProt	complete
involved_in	GO:0042276	error-prone translesion synthesis	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000117876 UniProtKB:Q9UBT6 WB:WBGene00017696	P	Seeded From UniProt	complete
involved_in	GO:0019985	translesion synthesis	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG13141 PANTHER:PTN000117876 PomBase:SPCC553.07c UniProtKB:Q9UBT6 WB:WBGene00017696	P	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1349767 PANTHER:PTN000118109	C	Seeded From UniProt	complete
enables	GO:0003887	DNA-directed DNA polymerase activity	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG13141 PANTHER:PTN000117876 TAIR:locus:2031050	F	Seeded From UniProt	complete
colocalizes_with	GO:0090734	site of DNA damage	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q9UBT6	C	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0042276	error-prone translesion synthesis	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q9UBT6	P	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0034644	cellular response to UV	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q9UBT6	P	Seeded From UniProt	complete
part_of	GO:0016604	nuclear body	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q9UBT6	C	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0006974	cellular response to DNA damage stimulus	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q9UBT6	P	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0006297	nucleotide-excision repair, DNA gap filling	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q9UBT6	P	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0006281	DNA repair	PMID:12555660^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2445458	P	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0006281	DNA repair	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q9UBT6	P	Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q9UBT6	C	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:12555660^[2]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
part_of	GO:0090734	site of DNA damage	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9UBT6 ensembl:ENSP00000241436	C	Seeded From UniProt	complete
involved_in	GO:0042276	error-prone translesion synthesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9UBT6 ensembl:ENSP00000241436	P	Seeded From UniProt	complete
involved_in	GO:0034644	cellular response to UV	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9UBT6 ensembl:ENSP00000241436	P	Seeded From UniProt	complete
part_of	GO:0016604	nuclear body	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9UBT6 ensembl:ENSP00000241436	C	Seeded From UniProt	complete
involved_in	GO:0006974	cellular response to DNA damage stimulus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9UBT6 ensembl:ENSP00000241436	P	Seeded From UniProt	complete
involved_in	GO:0006297	nucleotide-excision repair, DNA gap filling	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9UBT6 ensembl:ENSP00000241436	P	Seeded From UniProt	complete
involved_in	GO:0006281	DNA repair	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9UBT6 ensembl:ENSP00000241436	P	Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9UBT6 ensembl:ENSP00000241436	C	Seeded From UniProt	complete
part_of	GO:0016604	nuclear body	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:A0A024RAP4 ensembl:ENSP00000241436	C	Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:A0A024RAP4 ensembl:ENSP00000241436	C	Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR006642	F	Seeded From UniProt	complete
enables	GO:0003684	damaged DNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR017961 InterPro:IPR036775	F	Seeded From UniProt	complete
enables	GO:0003887	DNA-directed DNA polymerase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR022880	F	Seeded From UniProt	complete
involved_in	GO:0006281	DNA repair	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001126 InterPro:IPR006642 InterPro:IPR017961 InterPro:IPR036775	P	Seeded From UniProt	complete
enables	GO:0003887	DNA-directed DNA polymerase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:2.7.7.7	F	Seeded From UniProt	complete
enables	GO:0003887	DNA-directed DNA polymerase activity	PMID:12555660^[2]	ECO:0000304	author statement supported by traceable reference used in manual assertion		F	Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0238	F	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C	Seeded From UniProt	complete
involved_in	GO:0006974	cellular response to DNA damage stimulus	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0227	P	Seeded From UniProt	complete
enables	GO:0016740	transferase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0808	F	Seeded From UniProt	complete
involved_in	GO:0071897	DNA biosynthetic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0237	P	Seeded From UniProt	complete
enables	GO:0003887	DNA-directed DNA polymerase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0239	F	Seeded From UniProt	complete
involved_in	GO:0006260	DNA replication	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0235	P	Seeded From UniProt	complete
enables	GO:0016779	nucleotidyltransferase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0548	F	Seeded From UniProt	complete
involved_in	GO:0006281	DNA repair	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0234	P	Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 Schenten, D et al. (2002) DNA polymerase kappa deficiency does not affect somatic hypermutation in mice. Eur. J. Immunol. 32 3152-60 PubMed GONUTS page

[PMID:21873635-1] 1.0 ^1.1 ^1.2 ^1.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:12555660-2] 2.0 ^2.1 ^2.2 Schenten, D et al. (2002) DNA polymerase kappa deficiency does not affect somatic hypermutation in mice. Eur. J. Immunol. 32 3152-60 PubMed GONUTS page

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MOUSE:POLK

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