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ECOLI:UMUC
Contents
| Species (Taxon ID) | Escherichia coli (strain K12). (83333) | |
| Gene Name(s) | umuC | |
| Protein Name(s) | Protein UmuC | |
| External Links | ||
| UniProt | P04152 | |
| EMBL | M10107 M13387 U00096 AP009048 | |
| PIR | E64864 | |
| RefSeq | NP_415702.1 YP_489451.1 | |
| ProteinModelPortal | P04152 | |
| SMR | P04152 | |
| DIP | DIP-11090N | |
| IntAct | P04152 | |
| MINT | MINT-1516814 | |
| STRING | 511145.b1184 | |
| PRIDE | P04152 | |
| EnsemblBacteria | AAC74268 BAA36031 | |
| GeneID | 12932822 946359 | |
| KEGG | ecj:Y75_p1156 eco:b1184 | |
| PATRIC | 32117614 | |
| EchoBASE | EB1049 | |
| EcoGene | EG11056 | |
| eggNOG | COG0389 | |
| HOGENOM | HOG000252172 | |
| InParanoid | P04152 | |
| KO | K03502 | |
| OMA | QETCVSR | |
| OrthoDB | EOG6CZQNH | |
| PhylomeDB | P04152 | |
| BioCyc | EcoCyc:EG11056-MONOMER ECOL316407:JW1173-MONOMER MetaCyc:EG11056-MONOMER | |
| PRO | PR:P04152 | |
| Proteomes | UP000000318 UP000000625 | |
| Genevestigator | P04152 | |
| GO | GO:0016021 GO:0003684 GO:0003887 GO:0006974 GO:0000012 GO:0009432 | |
| Gene3D | 3.30.1490.100 | |
| InterPro | IPR017961 IPR001126 IPR017963 IPR025188 IPR024728 | |
| Pfam | PF13438 PF00817 PF11799 PF11798 | |
| SUPFAM | SSF100879 | |
| PROSITE | PS50173 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0009432 |
SOS response |
ECO:0000314 |
P |
the purified UmuD'2C complex was used to reconstitute an SOS lesion bypass system in vitro and found that no lesions occured. |
complete | |||||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006974 |
cellular response to DNA damage stimulus |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0019985 |
translesion synthesis |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0019985 |
translesion synthesis |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009432 |
SOS response |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0009355 |
DNA polymerase V complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0009355 |
DNA polymerase V complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008094 |
DNA-dependent ATPase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003887 |
DNA-directed DNA polymerase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003697 |
single-stranded DNA binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003684 |
damaged DNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006281 |
DNA repair |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006974 |
cellular response to DNA damage stimulus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009432 |
SOS response |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006281 |
DNA repair |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Tang, M et al. (1998) Biochemical basis of SOS-induced mutagenesis in Escherichia coli: reconstitution of in vitro lesion bypass dependent on the UmuD'2C mutagenic complex and RecA protein. Proc. Natl. Acad. Sci. U.S.A. 95 9755-60 PubMed GONUTS page
- ↑ 2.0 2.1 Woodgate, R et al. (1989) UmuC mutagenesis protein of Escherichia coli: purification and interaction with UmuD and UmuD'. Proc. Natl. Acad. Sci. U.S.A. 86 7301-5 PubMed GONUTS page
- ↑ 3.0 3.1 Fernández De Henestrosa, AR et al. (2000) Identification of additional genes belonging to the LexA regulon in Escherichia coli. Mol. Microbiol. 35 1560-72 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Reuven, NB et al. (1999) The mutagenesis protein UmuC is a DNA polymerase activated by UmuD', RecA, and SSB and is specialized for translesion replication. J. Biol. Chem. 274 31763-6 PubMed GONUTS page
- ↑ 5.0 5.1 Tang, M et al. (1999) UmuD'(2)C is an error-prone DNA polymerase, Escherichia coli pol V. Proc. Natl. Acad. Sci. U.S.A. 96 8919-24 PubMed GONUTS page
- ↑ Erdem, AL et al. (2014) DNA polymerase V activity is autoregulated by a novel intrinsic DNA-dependent ATPase. Elife 3 e02384 PubMed GONUTS page
- ↑ Robinson, A et al. (2015) Regulation of Mutagenic DNA Polymerase V Activation in Space and Time. PLoS Genet. 11 e1005482 PubMed GONUTS page
- ↑ Bruck, I et al. (1996) Purification of a soluble UmuD'C complex from Escherichia coli. Cooperative binding of UmuD'C to single-stranded DNA. J. Biol. Chem. 271 10767-74 PubMed GONUTS page
