CHICK:PCNA

Species (Taxon ID)	Gallus gallus (Chicken). (9031)
Gene Name(s)	PCNA
Protein Name(s)	Proliferating cell nuclear antigen PCNA
External Links
UniProt	Q9DEA3
EMBL	AB053163
RefSeq	NP_989501.1
UniGene	Gga.4036
ProteinModelPortal	Q9DEA3
SMR	Q9DEA3
BioGrid	675031
STRING	9031.ENSGALP00000040305
PaxDb	Q9DEA3
PRIDE	Q9DEA3
Ensembl	ENSGALT00000000225
GeneID	373984
KEGG	gga:373984
CTD	5111
eggNOG	COG0592
GeneTree	ENSGT00390000004965
HOGENOM	HOG000211098
HOVERGEN	HBG000947
InParanoid	Q9DEA3
KO	K04802
OMA	VTFVFES
OrthoDB	EOG7JX34W
PhylomeDB	Q9DEA3
Reactome	REACT_115867 REACT_116049 REACT_197098 REACT_197458 REACT_204174 REACT_216249 REACT_227032 REACT_241356 REACT_245426 REACT_249594 REACT_251811 REACT_252616 REACT_254546
NextBio	20813513
PRO	PR:Q9DEA3
Proteomes	UP000000539
GO	GO:0005813 GO:0005737 GO:0070062 GO:0043596 GO:0005654 GO:0005634 GO:0043626 GO:0070557 GO:0032139 GO:0030337 GO:0000701 GO:0006281 GO:0030855 GO:0006272 GO:0006298 GO:0032077 GO:0006275 GO:0019985
HAMAP	MF_00317
InterPro	IPR000730 IPR022649 IPR022659 IPR022648
PANTHER	PTHR11352
Pfam	PF02747 PF00705
PRINTS	PR00339
TIGRFAMs	TIGR00590
PROSITE	PS01251 PS00293

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
part_of	GO:0000785	chromatin	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P12004	C		Seeded From UniProt	complete
enables	GO:0003682	chromatin binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P12004	F		Seeded From UniProt	complete
enables	GO:0019899	enzyme binding	PMID:11453553^[1]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:O42130	F		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:17534940^[2]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(UBERON:0003051)\|part_of:(UBERON:0013731)	Seeded From UniProt	complete
part_of	GO:0070557	PCNA-p21 complex	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P12004	C		Seeded From UniProt	complete
involved_in	GO:0019985	translesion synthesis	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P12004	P		Seeded From UniProt	complete
part_of	GO:0043626	PCNA complex	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000143422 PomBase:SPBC16D10.09 SGD:S000000292 UniProtKB:P12004	C		Seeded From UniProt	complete
enables	GO:0030337	DNA polymerase processivity factor activity	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000143422 PomBase:SPBC16D10.09 SGD:S000000292	F		Seeded From UniProt	complete
involved_in	GO:0019985	translesion synthesis	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000143427 UniProtKB:P12004	P		Seeded From UniProt	complete
involved_in	GO:0006298	mismatch repair	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000143427 SGD:S000000292 UniProtKB:P12004	P		Seeded From UniProt	complete
involved_in	GO:0006272	leading strand elongation	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000143422 SGD:S000000292	P		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:21873635^[3]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0005655 FB:FBgn0032813 MGI:MGI:97503 PANTHER:PTN000143427 RGD:3269 SGD:S000000292 TAIR:locus:2025062 UniProtKB:P12004 UniProtKB:P17070 UniProtKB:P61074 UniProtKB:Q9DEA3 ZFIN:ZDB-GENE-000210-8 dictyBase:DDB_G0287607	C		Seeded From UniProt	complete
part_of	GO:0070557	PCNA-p21 complex	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12004 ensembl:ENSP00000368458	C		Seeded From UniProt	complete
enables	GO:0070182	DNA polymerase binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12004 ensembl:ENSP00000368458	F		Seeded From UniProt	complete
involved_in	GO:0045740	positive regulation of DNA replication	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12004 ensembl:ENSP00000368458	P		Seeded From UniProt	complete
involved_in	GO:0045739	positive regulation of DNA repair	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12004 ensembl:ENSP00000368458	P		Seeded From UniProt	complete
part_of	GO:0043626	PCNA complex	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12004 ensembl:ENSP00000368458	C		Seeded From UniProt	complete
part_of	GO:0043596	nuclear replication fork	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12004 ensembl:ENSP00000368458	C		Seeded From UniProt	complete
enables	GO:0042802	identical protein binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12004 ensembl:ENSP00000368458	F		Seeded From UniProt	complete
enables	GO:0035035	histone acetyltransferase binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12004 ensembl:ENSP00000368458	F		Seeded From UniProt	complete
involved_in	GO:0034644	cellular response to UV	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12004 ensembl:ENSP00000368458	P		Seeded From UniProt	complete
enables	GO:0032405	MutLalpha complex binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12004 ensembl:ENSP00000368458	F		Seeded From UniProt	complete
enables	GO:0032139	dinucleotide insertion or deletion binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12004 ensembl:ENSP00000368458	F		Seeded From UniProt	complete
involved_in	GO:0032077	positive regulation of deoxyribonuclease activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12004 ensembl:ENSP00000368458	P		Seeded From UniProt	complete
enables	GO:0030971	receptor tyrosine kinase binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12004 ensembl:ENSP00000368458	F		Seeded From UniProt	complete
involved_in	GO:0030855	epithelial cell differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12004 ensembl:ENSP00000368458	P		Seeded From UniProt	complete
involved_in	GO:0019985	translesion synthesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12004 ensembl:ENSP00000368458	P		Seeded From UniProt	complete
enables	GO:0019899	enzyme binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12004 ensembl:ENSP00000368458	F		Seeded From UniProt	complete
part_of	GO:0016604	nuclear body	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12004 ensembl:ENSP00000368458	C		Seeded From UniProt	complete
involved_in	GO:0006298	mismatch repair	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12004 ensembl:ENSP00000368458	P		Seeded From UniProt	complete
part_of	GO:0005813	centrosome	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12004 ensembl:ENSP00000368458	C		Seeded From UniProt	complete
part_of	GO:0005657	replication fork	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12004 ensembl:ENSP00000368458	C		Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12004 ensembl:ENSP00000368458	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12004 ensembl:ENSP00000368458	C		Seeded From UniProt	complete
enables	GO:0003684	damaged DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12004 ensembl:ENSP00000368458	F		Seeded From UniProt	complete
enables	GO:0003682	chromatin binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12004 ensembl:ENSP00000368458	F		Seeded From UniProt	complete
part_of	GO:0000785	chromatin	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12004 ensembl:ENSP00000368458	C		Seeded From UniProt	complete
enables	GO:0000701	purine-specific mismatch base pair DNA N-glycosylase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P12004 ensembl:ENSP00000368458	F		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000730 InterPro:IPR022648 InterPro:IPR022649	F		Seeded From UniProt	complete
involved_in	GO:0006275	regulation of DNA replication	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000730 InterPro:IPR022648 InterPro:IPR022649	P		Seeded From UniProt	complete
enables	GO:0030337	DNA polymerase processivity factor activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000730	F		Seeded From UniProt	complete
involved_in	GO:0006281	DNA repair	Reactome:R-GGA-353377	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	Reactome:R-GGA-353476 Reactome:R-GGA-216988	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0006260	DNA replication	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0235	P		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0238	F		Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ Niimi, A et al. (2001) Co-localization of chicken DNA topoisomerase IIalpha, but not beta, with sites of DNA replication and possible involvement of a C-terminal region of alpha through its binding to PCNA. Chromosoma 110 102-14 PubMed GONUTS page
↑ Neves, J et al. (2007) Differential expression of Sox2 and Sox3 in neuronal and sensory progenitors of the developing inner ear of the chick. J. Comp. Neurol. 503 487-500 PubMed GONUTS page
↑ ^3.0 ^3.1 ^3.2 ^3.3 ^3.4 ^3.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:11453553-1] Niimi, A et al. (2001) Co-localization of chicken DNA topoisomerase IIalpha, but not beta, with sites of DNA replication and possible involvement of a C-terminal region of alpha through its binding to PCNA. Chromosoma 110 102-14 PubMed GONUTS page

[PMID:17534940-2] Neves, J et al. (2007) Differential expression of Sox2 and Sox3 in neuronal and sensory progenitors of the developing inner ear of the chick. J. Comp. Neurol. 503 487-500 PubMed GONUTS page

[PMID:21873635-3] 3.0 ^3.1 ^3.2 ^3.3 ^3.4 ^3.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

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CHICK:PCNA

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Annotations

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References

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