ECOLI:DPO4

Species (Taxon ID)	Escherichia coli (strain K12). (83333)
Gene Name(s)	dinB (synonyms: dinP)
Protein Name(s)	DNA polymerase IV Pol IV
External Links
UniProt	Q47155
EMBL	D38582 U70214 U00096 AP009048 AF483080 AF483081 AF483082 AF483083 AF483084 AF483085 AF483086 AF483087 AF483088 AF483089 AF483090 AF483091 AF483092 AF483093 AF483094 AF483095 AF483096 AF483097 AF483098 AF483099 AF483100 AF483101 AF483102 AF483103 AF483104 AF483105
PIR	H64747
RefSeq	NP_414766.1 YP_488526.1
PDB	1OK7 1UNN 4IR1 4IR9 4IRC 4IRD 4IRK
PDBsum	1OK7 1UNN 4IR1 4IR9 4IRC 4IRD 4IRK
ProteinModelPortal	Q47155
SMR	Q47155
IntAct	Q47155
EnsemblBacteria	AAC73335 BAA77901
GeneID	12932684 944922
KEGG	ecj:Y75_p0222 eco:b0231
PATRIC	32115577
EchoBASE	EB2935
EcoGene	EG13141
InParanoid	Q47155
KO	K02346
OMA	EIRQRVY
OrthoDB	EOG6FZ4D8
PhylomeDB	Q47155
BioCyc	EcoCyc:G6115-MONOMER ECOL316407:JW0221-MONOMER MetaCyc:G6115-MONOMER
EvolutionaryTrace	Q47155
PRO	PR:Q47155
Proteomes	UP000000318 UP000000625
Genevestigator	Q47155
GO	GO:0005737 GO:0003684 GO:0003887 GO:0000287 GO:0006974 GO:0000731 GO:0006261 GO:0009432 GO:0019985
Gene3D	3.30.1490.100
HAMAP	MF_01113
InterPro	IPR017961 IPR001126 IPR017963 IPR022880 IPR024728
Pfam	PF00817 PF11799 PF11798
SUPFAM	SSF100879
PROSITE	PS50173

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
involved_in	GO:0042276	error-prone translesion synthesis	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000117876 UniProtKB:Q9UBT6 WB:WBGene00017696	P	Seeded From UniProt	complete
involved_in	GO:0019985	translesion synthesis	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG13141 PANTHER:PTN000117876 PomBase:SPCC553.07c UniProtKB:Q9UBT6 WB:WBGene00017696	P	Seeded From UniProt	complete
involved_in	GO:0009432	SOS response	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG13141 PANTHER:PTN000118165 UniProtKB:Q74CQ6 UniProtKB:Q8Y5T0	P	Seeded From UniProt	complete
part_of	GO:0005829	cytosol	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000118165 UniProtKB:P9WNT1 UniProtKB:P9WNT3	C	Seeded From UniProt	complete
enables	GO:0003887	DNA-directed DNA polymerase activity	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	EcoGene:EG13141 PANTHER:PTN000117876 TAIR:locus:2031050	F	Seeded From UniProt	complete
involved_in	GO:0006974	cellular response to DNA damage stimulus	PMID:11967071^[2]	ECO:0000270	expression pattern evidence used in manual assertion		P	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	PMID:10488344^[3]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
enables	GO:0003887	DNA-directed DNA polymerase activity	PMID:10488344^[3]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt	complete
involved_in	GO:0000731	DNA synthesis involved in DNA repair	PMID:10488344^[3]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0019985	translesion synthesis	PMID:10801133^[4]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0009432	SOS response	PMID:10801133^[4]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0009432	SOS response	PMID:6771759^[5]	ECO:0000270	expression pattern evidence used in manual assertion		P	Seeded From UniProt	complete
enables	GO:0003887	DNA-directed DNA polymerase activity	PMID:10488344^[3]	ECO:0000314	direct assay evidence used in manual assertion		F	Seeded From UniProt	complete
enables	GO:0003684	damaged DNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR017961 InterPro:IPR036775	F	Seeded From UniProt	complete
enables	GO:0003887	DNA-directed DNA polymerase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR022880	F	Seeded From UniProt	complete
involved_in	GO:0006281	DNA repair	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001126 InterPro:IPR017961 InterPro:IPR036775	P	Seeded From UniProt	complete
enables	GO:0003887	DNA-directed DNA polymerase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:2.7.7.7	F	Seeded From UniProt	complete
involved_in	GO:0006281	DNA repair	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000100659	P	Seeded From UniProt	complete
involved_in	GO:0006261	DNA-dependent DNA replication	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000100659	P	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000100659	C	Seeded From UniProt	complete
enables	GO:0000287	magnesium ion binding	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000100659	F	Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000100659	F	Seeded From UniProt	complete
enables	GO:0003887	DNA-directed DNA polymerase activity	GO_REF:0000104	ECO:0000256	match to sequence model evidence used in automatic assertion	UniRule:UR000100659	F	Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0238	F	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C	Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F	Seeded From UniProt	complete
involved_in	GO:0006281	DNA repair	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0234	P	Seeded From UniProt	complete
enables	GO:0016779	nucleotidyltransferase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0548	F	Seeded From UniProt	complete
involved_in	GO:0006974	cellular response to DNA damage stimulus	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0227	P	Seeded From UniProt	complete
enables	GO:0003887	DNA-directed DNA polymerase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0239	F	Seeded From UniProt	complete
involved_in	GO:0006260	DNA replication	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0235	P	Seeded From UniProt	complete
enables	GO:0016740	transferase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0808	F	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ Khil, PP & Camerini-Otero, RD (2002) Over 1000 genes are involved in the DNA damage response of Escherichia coli. Mol. Microbiol. 44 89-105 PubMed GONUTS page
↑ ^3.0 ^3.1 ^3.2 ^3.3 Wagner, J et al. (1999) The dinB gene encodes a novel E. coli DNA polymerase, DNA pol IV, involved in mutagenesis. Mol. Cell 4 281-6 PubMed GONUTS page
↑ ^4.0 ^4.1 Tang, M et al. (2000) Roles of E. coli DNA polymerases IV and V in lesion-targeted and untargeted SOS mutagenesis. Nature 404 1014-8 PubMed GONUTS page
↑ Kenyon, CJ & Walker, GC (1980) DNA-damaging agents stimulate gene expression at specific loci in Escherichia coli. Proc. Natl. Acad. Sci. U.S.A. 77 2819-23 PubMed GONUTS page

[PMID:21873635-1] 1.0 ^1.1 ^1.2 ^1.3 ^1.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:11967071-2] Khil, PP & Camerini-Otero, RD (2002) Over 1000 genes are involved in the DNA damage response of Escherichia coli. Mol. Microbiol. 44 89-105 PubMed GONUTS page

[PMID:10488344-3] 3.0 ^3.1 ^3.2 ^3.3 Wagner, J et al. (1999) The dinB gene encodes a novel E. coli DNA polymerase, DNA pol IV, involved in mutagenesis. Mol. Cell 4 281-6 PubMed GONUTS page

[PMID:10801133-4] 4.0 ^4.1 Tang, M et al. (2000) Roles of E. coli DNA polymerases IV and V in lesion-targeted and untargeted SOS mutagenesis. Nature 404 1014-8 PubMed GONUTS page

[PMID:6771759-5] Kenyon, CJ & Walker, GC (1980) DNA-damaging agents stimulate gene expression at specific loci in Escherichia coli. Proc. Natl. Acad. Sci. U.S.A. 77 2819-23 PubMed GONUTS page

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ECOLI:DPO4

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