HUMAN:POLI

Species (Taxon ID)	Homo sapiens (Human). (9606)
Gene Name(s)	POLI (synonyms: RAD30B)
Protein Name(s)	DNA polymerase iota Eta2 RAD30 homolog B
External Links
UniProt	Q9UNA4
EMBL	AY094607 AC093462 AF140501 AL136670 BC032662 AF245438
CCDS	CCDS11954.2
RefSeq	NP_009126.2
UniGene	Hs.438533
PDB	1T3N 1ZET 2ALZ 2DPI 2DPJ 2FLL 2FLN 2FLP 2KHU 2KHW 2KTF 2L0F 2L0G 2MBB 3EPG 3EPI 3G6V 3G6X 3G6Y 3GV5 3GV7 3GV8 3H40 3H4B 3H4D 3NGD 3OSN 3Q8P 3Q8Q 3Q8R 3Q8S 4EBC 4EBD 4EBE 4EYH 4EYI 4FS1 4FS2
PDBsum	1T3N 1ZET 2ALZ 2DPI 2DPJ 2FLL 2FLN 2FLP 2KHU 2KHW 2KTF 2L0F 2L0G 2MBB 3EPG 3EPI 3G6V 3G6X 3G6Y 3GV5 3GV7 3GV8 3H40 3H4B 3H4D 3NGD 3OSN 3Q8P 3Q8Q 3Q8R 3Q8S 4EBC 4EBD 4EBE 4EYH 4EYI 4FS1 4FS2
ProteinModelPortal	Q9UNA4
SMR	Q9UNA4
BioGrid	116370
IntAct	Q9UNA4
MINT	MINT-1189678
STRING	9606.ENSP00000217800
ChEMBL	CHEMBL5391
PhosphoSite	Q9UNA4
DMDM	327478565
MaxQB	Q9UNA4
PaxDb	Q9UNA4
PRIDE	Q9UNA4
DNASU	11201
Ensembl	ENST00000579534
GeneID	11201
KEGG	hsa:11201
UCSC	uc002lfj.4
CTD	11201
GeneCards	GC18P051795
H-InvDB	HIX0014457
HGNC	HGNC:9182
HPA	HPA012000
MIM	605252
neXtProt	NX_Q9UNA4
PharmGKB	PA33502
eggNOG	COG0389
GeneTree	ENSGT00530000062942
HOGENOM	HOG000234325
HOVERGEN	HBG053634
InParanoid	Q9UNA4
KO	K03510
OMA	CFCNLKA
OrthoDB	EOG7C8GGJ
PhylomeDB	Q9UNA4
TreeFam	TF324222
ChiTaRS	POLI
EvolutionaryTrace	Q9UNA4
GeneWiki	POLI
GenomeRNAi	11201
NextBio	42637
PRO	PR:Q9UNA4
Proteomes	UP000005640
Bgee	Q9UNA4
CleanEx	HS_POLI
ExpressionAtlas	Q9UNA4
Genevestigator	Q9UNA4
GO	GO:0005622 GO:0043231 GO:0005654 GO:0005634 GO:0003684 GO:0003887 GO:0046872 GO:0006281 GO:0006260
Gene3D	3.30.1490.100
InterPro	IPR017961 IPR001126 IPR017963
Pfam	PF00817 PF11799
SUPFAM	SSF100879
PROSITE	PS50173

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
part_of	GO:0005622	intracellular	GO_REF:0000054	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0036464	cytoplasmic ribonucleoprotein granule	GO_REF:0000052	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0016607	nuclear speck	GO_REF:0000052	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0003684	damaged DNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR017961 InterPro:IPR036775	F		Seeded From UniProt	complete
involved_in	GO:0006281	DNA repair	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001126 InterPro:IPR017961 InterPro:IPR036775	P		Seeded From UniProt	complete
enables	GO:0003887	DNA-directed DNA polymerase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:2.7.7.7	F		Seeded From UniProt	complete
involved_in	GO:0006281	DNA repair	PMID:10458907	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
	GO:0006281	DNA repair	PMID:10458907	ECO:0000314			P		mRNA transcript repair protein	complete
part_of	GO:0005654	nucleoplasm	PMID:10458907 Reactome:R-HSA-5656158 Reactome:R-HSA-5656148 Reactome:R-HSA-5656105 Reactome:R-HSA-5653770 Reactome:R-HSA-5653766 Reactome:R-HSA-5653756 Reactome:R-HSA-5653754	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0003887	DNA-directed DNA polymerase activity	PMID:10458907 Reactome:R-HSA-5656148	ECO:0000304	author statement supported by traceable reference used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0042276	error-prone translesion synthesis	Reactome:R-HSA-5656121	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0019985	translesion synthesis	Reactome:R-HSA-110313	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0071897	DNA biosynthetic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0237	P		Seeded From UniProt	complete
enables	GO:0016740	transferase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0808	F		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C		Seeded From UniProt	complete
enables	GO:0016779	nucleotidyltransferase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0548	F		Seeded From UniProt	complete
involved_in	GO:0006281	DNA repair	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0234	P		Seeded From UniProt	complete
enables	GO:0003677	DNA binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0238	F		Seeded From UniProt	complete
involved_in	GO:0006974	cellular response to DNA damage stimulus	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0227	P		Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F		Seeded From UniProt	complete
involved_in	GO:0006260	DNA replication	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0235	P		Seeded From UniProt	complete
enables	GO:0003887	DNA-directed DNA polymerase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0239	F		Seeded From UniProt	complete
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References

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