User:AlexFrancis

My Annotations

Status	Page	Date/Time	GO Term (Aspect)	Reference	Evidence	Notes	Links
acceptable	HUMAN:ALEX	2011-09-21 18:58:04 CDT	GO:0009966 regulation of signal transduction (P)	PMID:12719376	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 5A demonstrates the relationship between ALEX and XLalphas for the wild-type and mutant phenotype.	challenge
acceptable	HUMAN:HCST	2011-09-21 21:48:44 CDT	GO:0006468 protein phosphorylation (P)	PMID:10528161	ECO:0000316 genetic interaction evidence used in manual assertion	Fig 5A Shows that KAP10 cross-linking leads to Akt (PKB/RAC) phosphrylation Fig 5B shows that KAP10 is dependant upon PI-3 Kinase for phosphorylation activity to occur.	challenge
updatedbyinstructor	MOUSE:BL1S3	2011-09-23 12:08:12 CDT	GO:0008320 protein transmembrane transporter activity (F)	PMID:16837549	ECO:0000315 mutant phenotype evidence used in manual assertion	Incorrect annotation, see discussion page for explanation.	challenge
acceptable	ECOLI:SKP	2011-09-25 17:34:11 CDT	GO:0022417 protein maturation by protein folding (P)	PMID:9914480	ECO:0000314 direct assay evidence used in manual assertion	Fig. 4C shows the maturation on PhoE in Skp serum. Table 1 shows amount of PhoE folded based on incdreasing concentraions of Skp.	challenge
acceptable	HUMAN:NPC1	2011-10-03 19:53:48 CDT	GO:2000189 positive regulation of cholesterol homeostasis (P)	PMID:9927649	ECO:0000315 mutant phenotype evidence used in manual assertion	Fig 1,2 and Table 1 shows NPC-1's role in correcting the over accumulation of choloesterol in lysosomes versus the defective mutant	challenge
acceptable	XENLA:NOGG	2011-10-04 19:17:13 CDT	GO:0030514 negative regulation of BMP signaling pathway (P)	PMID:8752214	ECO:0000314 direct assay evidence used in manual assertion	Fig 1 shows noggins role in negative regulation of signal transduction.	challenge
unacceptable	HUMAN:AURKB	2011-10-21 20:18:25 CDT	GO:0032467 positive regulation of cytokinesis (P)	PMID:12458200	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 2 a-d shows Aurora-B's role in inhibiting Vimentin and promoting cytokinesis	challenge
acceptable	MOUSE:AP3S1	2011-11-01 19:24:47 CDT	GO:0016020 membrane (C)	PMID:16837549	ECO:0000315 mutant phenotype evidence used in manual assertion	Fig. 2	challenge
acceptable	MOUSE:BL1S1	2011-11-01 19:31:43 CDT	GO:0005769 early endosome (C)	PMID:16837549	ECO:0000314 direct assay evidence used in manual assertion	Fig. 3	challenge
acceptable	MOUSE:DTBP1	2011-11-01 20:09:08 CDT	GO:0043506 regulation of JUN kinase activity (P)	PMID:19094965	ECO:0000315 mutant phenotype evidence used in manual assertion	Fig. 3	challenge
acceptable	XENLA:CHK1	2011-11-15 19:57:48 CST	GO:0006468 protein phosphorylation (P)	PMID:10068474	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 3	challenge
acceptable	RAT:SH3G3	2011-11-15 20:35:25 CST	GO:0005769 early endosome (C)	PMID:17088211	ECO:0000314 direct assay evidence used in manual assertion	Fig 3	challenge
acceptable	RAT:ARC	2011-11-15 20:51:11 CST	GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity (P)	PMID:17088211	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 6	challenge

acceptable:11
unacceptable:1
requires_changes:0
flagged:0

Annotations challenged by AlexFrancis

Status	Author,Group	Page	GO Term (Aspect)	Reference	Evidence	Links	Page history
acceptable	JmicG, Team Mighty Morphin GO Annotators	MOUSE:REL1	GO:0060618 - nipple development (P)	PMID:9886856	ECO:0000315 mutant phenotype evidence used in manual assertion	challenge	C: 4
acceptable	JmicG, Team Mighty Morphin GO Annotators	MOUSE:REL1	GO:0060443 - mammary gland morphogenesis (P)	PMID:9886856	ECO:0000315 mutant phenotype evidence used in manual assertion	challenge	C: 3
acceptable	Vchhabria, Team KremlinOnTheCrum	HUMAN:MRE11	GO:0004520 - DNA endonuclease activity (F)	PMID:9705271	ECO:0000314 direct assay evidence used in manual assertion	challenge	C: 2
acceptable	Afg8920, Team Cheesesteak	HUMAN:BACH1	GO:0006281 - DNA repair (P)	PMID:11301010	ECO:0000315 mutant phenotype evidence used in manual assertion	challenge	C: 1
unacceptable	Jcooper, Team Attenuators	ECOLI:USPA	GO:0006950 - response to stress (P)	PMID:1453957	ECO:0000270 expression pattern evidence used in manual assertion	challenge	C: 1
acceptable	Lrodgers, Team KremlinOnTheCrum	BACSU:CLPP	GO:0004176 - ATP-dependent peptidase activity (F)	PMID:14763982	ECO:0000315 mutant phenotype evidence used in manual assertion	challenge	C: 2
acceptable	Oherrera, Team That Will Beat You!!!	HUMAN:TFR1	GO:0048471 - perinuclear region of cytoplasm (C)	PMID:20202662	ECO:0000314 direct assay evidence used in manual assertion	challenge	C: 1

0 annotations fixed by AlexFrancis