Category:Team Cheesesteak

Fig 3: the number of NT cells in thymus reduced 5-6x in mutant strain

Fig 1c: DPdull tetramers are derived from CD1d-mediated selection; they were no longer present in 9-day old mice thymi

Fig. 3 shows that FtnA releaves the production of hydroxyl free radicals by scavenging the iron

Fig 3F: lack of natural killer cell proliferation of RasGRP -/- mutant

Fig 1D, 1E: RasGRP1 is necessary for early NKC development

Fig 3; there is a pronounced lack of mature B cells in RAG-2 deficient mice

Figures 3 and 4: in particular the lack of anti-IgM and -IgD staining indicates that there are no mature B cells in the spleen or bone marrow

Fig 4; RasGRP inactivation in mutants led to no Ras activation

Fig 2; inhibition of mouse RasGRP1 led to impaired T-cell differentiation

Fig 4; overexpression of RasGRP1 -> hypersensitive Jurkat cells. However, we observed that RasGRP can activate Ras in vivo even in the presence of EGTA plus BAPTA/AM, compounds that sequester extracellular and intracellular calcium, respectively (data not shown).

Fig. 3 shows the optimizing reaction conditions for HCV NS3 RNA helicase

Fig 3e; overexpression of RasGRP1 was induced to determine the protein's normal function

Fig 3; mutant and wild-type compared to determine CAPRI's role in Ras activation;

Fig 5b; over- and underexpression to determine role of CAPRI; directly blocks Ras activation

Addition of RebF provides FADH2 for the halogenase to produce 7-chlorotryptophan during rebeccamycin biosynthesis

Fig. 1. shows inhibition by myostatin of human skeletal muscle cells (HuSkMC).

Figure 2; comparison of wild-type versus mutant allele

Figure 2; expression of non-functional allele in cattle

Fig 4a-d; disruption of GDF-8's normal functioning

Fig. 5 shows that the mutant interferes with BACH1 ability to timely repair double-strand breaks that BRCA1 usually makes.

Figure 1, 2BC, and Fig. 3C-E. Figure 3 in particular indicates that "proper localization and signaling through the adapter LAT are required for normal suppression of RAG gene expression".

Figure 1, Fig 2BC, Fig 3CE

Figure one shows that Akt activity in hippocampal neurons is regulated by PTEN

Figure 3

Figure 4 demonstrates that PCAF-mediates acetylation of PTEN lysines 125 and 128.

Fig 4B. Erk1/Erk2 phosphorylation (via MAPK) was delayed and reduced in RasGRP1- mutants.

Figure three shows CK2 phosphorylates the C terminus of PTEN.

Figure one shows the catalyzed unwinding of the oligonucleotide from the single-stranded circle

Figure 3 shows that Helicase II translocates along single-stranded DNA

in the 3' to 5' direction