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XENLA:NOGG

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Species (Taxon ID) Xenopus laevis (African clawed frog). (8355)
Gene Name(s) nog
Protein Name(s) Noggin
External Links
UniProt P49011
EMBL M98807
PIR A43343
RefSeq NP_001079113.1
UniGene Xl.834
ProteinModelPortal P49011
SMR P49011
GeneID 373646
KEGG xla:373646
CTD 9241
Xenbase XB-GENE-864891
HOVERGEN HBG006514
KO K04658
GO GO:0005576
GO:0051216
GO:0030154
GO:0007517
GO:0045596
Gene3D 2.10.90.10
InterPro IPR029034
IPR008717
PANTHER PTHR10494
Pfam PF05806
PIRSF PIRSF008129
SUPFAM SSF57501

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0030514

negative regulation of BMP signaling pathway

PMID:8752214[1]

ECO:0000314

P

Fig 1 shows noggins role in negative regulation of signal transduction.

complete
CACAO 2096

involved_in

GO:0030514

negative regulation of BMP signaling pathway

PMID:8752214[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0007517

muscle organ development

PMID:11737146[2]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:Q8AV66

P

Seeded From UniProt

complete

involved_in

GO:0030514

negative regulation of BMP signaling pathway

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR008717

P

Seeded From UniProt

complete

involved_in

GO:0045596

negative regulation of cell differentiation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR008717

P

Seeded From UniProt

complete

involved_in

GO:0051216

cartilage development

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0891

P

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964
UniProtKB-SubCell:SL-0243

C

Seeded From UniProt

complete

involved_in

GO:0030154

cell differentiation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0221

P

Seeded From UniProt

complete

involved_in

GO:0007275

multicellular organism development

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0217

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Zimmerman, LB et al. (1996) The Spemann organizer signal noggin binds and inactivates bone morphogenetic protein 4. Cell 86 599-606 PubMed GONUTS page
  2. Uchiyama, H et al. (2001) Cloning and characterization of the T-box gene Tbx6 in Xenopus laevis. Dev. Growth Differ. 43 657-69 PubMed GONUTS page