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RAT:SH3G3
Contents
| Species (Taxon ID) | Rattus norvegicus (Rat). (10116) | |
| Gene Name(s) | Sh3gl3 (synonyms: Sh3d2c1, Sh3p13) | |
| Protein Name(s) | Endophilin-A3
Endophilin-3 SH3 domain protein 2C SH3 domain-containing GRB2-like protein 3 SH3p13 | |
| External Links | ||
| UniProt | O35180 | |
| EMBL | AC128742 AF009604 AB008159 | |
| RefSeq | XP_006229542.1 XP_006229547.1 | |
| UniGene | Rn.5909 | |
| ProteinModelPortal | O35180 | |
| SMR | O35180 | |
| IntAct | O35180 | |
| MINT | MINT-1526354 | |
| STRING | 10116.ENSRNOP00000026870 | |
| PRIDE | O35180 | |
| GeneID | 81921 | |
| KEGG | rno:81921 | |
| CTD | 6457 | |
| RGD | 620578 | |
| eggNOG | NOG307129 | |
| HOGENOM | HOG000231641 | |
| HOVERGEN | HBG052866 | |
| InParanoid | O35180 | |
| KO | K11247 | |
| PhylomeDB | O35180 | |
| PRO | PR:O35180 | |
| Proteomes | UP000002494 | |
| ExpressionAtlas | O35180 | |
| Genevestigator | O35180 | |
| GO | GO:0031901 GO:0070062 GO:0008289 GO:0006897 | |
| Gene3D | 1.20.1270.60 | |
| InterPro | IPR027267 IPR004148 IPR028501 IPR001452 | |
| PANTHER | PTHR10661:SF120 | |
| Pfam | PF03114 PF14604 | |
| PRINTS | PR00452 | |
| SMART | SM00721 SM00326 | |
| SUPFAM | SSF50044 | |
| PROSITE | PS51021 PS50002 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0005769 |
early endosome |
ECO:0000314 |
C |
Fig 3 |
complete | |||||
|
part_of |
GO:0005769 |
early endosome |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0099092 |
postsynaptic density, intracellular component |
ECO:0006063 |
over expression analysis evidence used in manual assertion |
C |
|
Seeded From UniProt |
complete | ||
|
part_of |
GO:0099092 |
postsynaptic density, intracellular component |
ECO:0006003 |
electron microscopy evidence used in manual assertion |
C |
|
Seeded From UniProt |
complete | ||
|
part_of |
GO:0099092 |
postsynaptic density, intracellular component |
ECO:0005589 |
confocal microscopy evidence used in manual assertion |
C |
|
Seeded From UniProt |
complete | ||
|
part_of |
GO:0098978 |
glutamatergic synapse |
ECO:0006063 |
over expression analysis evidence used in manual assertion |
C |
part_of:(UBERON:0002421) |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0098978 |
glutamatergic synapse |
ECO:0006003 |
electron microscopy evidence used in manual assertion |
C |
part_of:(UBERON:0002421) |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0098978 |
glutamatergic synapse |
ECO:0005589 |
confocal microscopy evidence used in manual assertion |
C |
part_of:(UBERON:0002421) |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0098845 |
postsynaptic endosome |
ECO:0006063 |
over expression analysis evidence used in manual assertion |
C |
|
Seeded From UniProt |
complete | ||
|
part_of |
GO:0098845 |
postsynaptic endosome |
ECO:0005589 |
confocal microscopy evidence used in manual assertion |
C |
|
Seeded From UniProt |
complete | ||
|
involved_in |
GO:2000369 |
regulation of clathrin-dependent endocytosis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:1900186 |
negative regulation of clathrin-dependent endocytosis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0098793 |
presynapse |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0045666 |
positive regulation of neuron differentiation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0045202 |
synapse |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008022 |
protein C-terminus binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
RGD:1347795 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0001669 |
acrosomal vesicle |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0042802 |
identical protein binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q99963 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006897 |
endocytosis |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005768 |
endosome |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006897 |
endocytosis |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008289 |
lipid binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0031901 |
early endosome membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 1.9 Chowdhury, S et al. (2006) Arc/Arg3.1 interacts with the endocytic machinery to regulate AMPA receptor trafficking. Neuron 52 445-59 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Sugiura, H et al. (2004) Inhibitory role of endophilin 3 in receptor-mediated endocytosis. J. Biol. Chem. 279 23343-8 PubMed GONUTS page
- ↑ De Gois, S et al. () Identification of endophilins 1 and 3 as selective binding partners for VGLUT1 and their co-localization in neocortical glutamatergic synapses: implications for vesicular glutamate transporter trafficking and excitatory vesicle formation. Cell. Mol. Neurobiol. 26 679-93 PubMed GONUTS page
- ↑ Tian, Q et al. (2012) Endophilin isoforms have distinct characteristics in interactions with N-type Ca2+ channels and dynamin I. Neurosci Bull 28 483-92 PubMed GONUTS page
- ↑ Qiao, Y et al. (2004) Characterization of rtSH3p13 gene encoding a development protein involved in vesicular traffic in spermiogenesis. Cell Res. 14 197-207 PubMed GONUTS page
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