User:Afg8920

My Annotations

Status	Page	Date/Time	GO Term (Aspect)	Reference	Evidence	Notes	Links
acceptable	ECOLI:UVRD	2011-09-24 21:09:35 CDT	GO:0003678 DNA helicase activity (F)	PMID:2942537	ECO:0000314 direct assay evidence used in manual assertion	Figure 3 shows that Helicase II translocates along single-stranded DNA in the 3' to 5' direction	challenge
acceptable	ECOLI:RUVB	2011-09-24 22:47:14 CDT	GO:0004003 ATP-dependent DNA helicase activity (F)	PMID:8433990	ECO:0000314 direct assay evidence used in manual assertion	Figure one shows the catalyzed unwinding of the oligonucleotide from the single-stranded circle	challenge
acceptable	HUMAN:CSK21	2011-10-04 19:46:28 CDT	GO:0004674 protein serine/threonine kinase activity (F)	PMID:11035045	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure three shows CK2 phosphorylates the C terminus of PTEN.	challenge
acceptable	HUMAN:KAT2B	2011-10-04 20:08:33 CDT	GO:0004402 histone acetyltransferase activity (F)	PMID:16829519	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure 4 demonstrates that PCAF-mediates acetylation of PTEN lysines 125 and 128.	challenge
unacceptable	HUMAN:PTEN	2011-10-04 20:30:49 CDT	GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity (F)	PMID:12622404	ECO:0000315 mutant phenotype evidence used in manual assertion	Figure one shows that Akt activity in hippocampal neurons is regulated by PTEN	challenge
acceptable	HUMAN:BACH1	2011-10-18 19:26:15 CDT	GO:0006281 DNA repair (P)	PMID:11301010	ECO:0000315 mutant phenotype evidence used in manual assertion	Fig. 5 shows that the mutant interferes with BACH1 ability to timely repair double-strand breaks that BRCA1 usually makes.	challenge
acceptable	HUMAN:TGFB1	2011-10-18 20:51:45 CDT	GO:0045596 negative regulation of cell differentiation (P)	PMID:19357233	ECO:0000270 expression pattern evidence used in manual assertion	Fig. 1. shows inhibition by myostatin of human skeletal muscle cells (HuSkMC).	challenge
acceptable	NOCAE:REBF	2011-11-01 20:04:54 CDT	GO:0042602 flavin reductase activity (F)	PMID:15743914	ECO:0000314 direct assay evidence used in manual assertion	Addition of RebF provides FADH2 for the halogenase to produce 7-chlorotryptophan during rebeccamycin biosynthesis	challenge
acceptable	HCVJA:POLG	2011-11-01 20:22:31 CDT	GO:0003724 RNA helicase activity (F)	PMID:8970970	ECO:0000314 direct assay evidence used in manual assertion	Fig. 3 shows the optimizing reaction conditions for HCV NS3 RNA helicase	challenge
acceptable	ECOLI:FTNA	2011-11-15 20:21:42 CST	GO:0006979 iron-sulfur cluster assembly (P)	PMID:18618270	ECO:0000314 direct assay evidence used in manual assertion	Fig. 3 shows that FtnA releaves the production of hydroxyl free radicals by scavenging the iron	challenge

acceptable:9
unacceptable:1
requires_changes:0
flagged:0

Annotations challenged by Afg8920

Status	Author,Group	Page	GO Term (Aspect)	Reference	Evidence	Links	Page history

0 annotations fixed by Afg8920