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ECOLI:FTNA
Contents
Species (Taxon ID) | Escherichia coli (strain K12). (83333) | |
Gene Name(s) | ftnA (synonyms: ftn, gen-165, rsgA) | |
Protein Name(s) | Bacterial non-heme ferritin
Ferritin-1 | |
External Links | ||
UniProt | P0A998 | |
EMBL | X53513 U00096 AP009048 U35066 | |
PIR | S14069 | |
RefSeq | NP_416418.1 YP_490165.1 | |
PDB | 1EUM | |
PDBsum | 1EUM | |
ProteinModelPortal | P0A998 | |
SMR | P0A998 | |
DIP | DIP-36198N | |
IntAct | P0A998 | |
STRING | 511145.b1905 | |
PaxDb | P0A998 | |
PRIDE | P0A998 | |
EnsemblBacteria | AAC74975 BAA15728 | |
GeneID | 12934013 946410 | |
KEGG | ecj:Y75_p1879 eco:b1905 | |
PATRIC | 32119139 | |
EchoBASE | EB0914 | |
EcoGene | EG10921 | |
eggNOG | COG1528 | |
HOGENOM | HOG000223382 | |
InParanoid | P0A998 | |
KO | K02217 | |
OMA | CEDKGFE | |
OrthoDB | EOG6G4W12 | |
PhylomeDB | P0A998 | |
BioCyc | EcoCyc:EG10921-MONOMER ECOL316407:JW1893-MONOMER MetaCyc:EG10921-MONOMER | |
EvolutionaryTrace | P0A998 | |
PRO | PR:P0A998 | |
Proteomes | UP000000318 UP000000625 | |
Genevestigator | P0A998 | |
GO | GO:0005829 GO:0008199 GO:0004322 GO:0042802 GO:0006974 GO:0006880 GO:0006826 GO:0006979 | |
Gene3D | 1.20.1260.10 | |
InterPro | IPR001519 IPR009040 IPR009078 IPR012347 IPR008331 | |
PANTHER | PTHR11431 | |
Pfam | PF00210 | |
SUPFAM | SSF47240 | |
PROSITE | PS50905 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
GO:0006979 |
iron-sulfur cluster assembly |
ECO:0000314 |
P |
Fig. 3 shows that FtnA releaves the production of hydroxyl free radicals by scavenging the iron |
complete | |||||
GO:0034986 |
iron chaperone activity |
ECO:0000314 |
F |
Figure 6 shows that IscA can retrieve iron from the iron-bound FtnA. |
complete | |||||
involved_in |
GO:0006979 |
response to oxidative stress |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005829 |
cytosol |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0071281 |
cellular response to iron ion |
ECO:0001204 |
in vitro transcription assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0071281 |
cellular response to iron ion |
ECO:0000279 |
western blot evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0042802 |
identical protein binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10921 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0008199 |
ferric iron binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10921 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0008198 |
ferrous iron binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000153092 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0006880 |
intracellular sequestering of iron ion |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10921 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005829 |
cytosol |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10921 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000153092 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0005506 |
iron ion binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:95588 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0004322 |
ferroxidase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG10921 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0006974 |
cellular response to DNA damage stimulus |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0042802 |
identical protein binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0008199 |
ferric iron binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006880 |
intracellular sequestering of iron ion |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005829 |
cytosol |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0004322 |
ferroxidase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006826 |
iron ion transport |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006879 |
cellular iron ion homeostasis |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0008199 |
ferric iron binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006879 |
cellular iron ion homeostasis |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0016491 |
oxidoreductase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Bitoun, JP et al. (2008) Escherichia coli FtnA acts as an iron buffer for re-assembly of iron-sulfur clusters in response to hydrogen peroxide stress. Biometals 21 693-703 PubMed GONUTS page
- ↑ Lasserre, JP et al. (2006) A complexomic study of Escherichia coli using two-dimensional blue native/SDS polyacrylamide gel electrophoresis. Electrophoresis 27 3306-21 PubMed GONUTS page
- ↑ 3.0 3.1 Nandal, A et al. (2010) Induction of the ferritin gene (ftnA) of Escherichia coli by Fe(2+)-Fur is mediated by reversal of H-NS silencing and is RyhB independent. Mol. Microbiol. 75 637-57 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 4.4 4.5 4.6 4.7 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ Khil, PP & Camerini-Otero, RD (2002) Over 1000 genes are involved in the DNA damage response of Escherichia coli. Mol. Microbiol. 44 89-105 PubMed GONUTS page
- ↑ 6.0 6.1 Hudson, AJ et al. (1993) Overproduction, purification and characterization of the Escherichia coli ferritin. Eur. J. Biochem. 218 985-95 PubMed GONUTS page
- ↑ Abdul-Tehrani, H et al. (1999) Ferritin mutants of Escherichia coli are iron deficient and growth impaired, and fur mutants are iron deficient. J. Bacteriol. 181 1415-28 PubMed GONUTS page
- ↑ Ishihama, Y et al. (2008) Protein abundance profiling of the Escherichia coli cytosol. BMC Genomics 9 102 PubMed GONUTS page
- ↑ Treffry, A et al. (1998) How the presence of three iron binding sites affects the iron storage function of the ferritin (EcFtnA) of Escherichia coli. FEBS Lett. 432 213-8 PubMed GONUTS page
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