GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

User:Jcooper

From GONUTS
Jump to: navigation, search

My Annotations

StatusPageDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
acceptableRHOCB:D5AQX92011-09-24 15:27:11 CDTGO:0000160 two-component signal transduction system (phosphorelay) (P)PMID:10347192ECO:0000314 direct assay evidence used in manual assertion

Figures 2, 3

challenge
acceptableRHOCB:D5AQX92011-09-25 14:04:34 CDTGO:0000156 two-component response regulator activity (F)PMID:10347192ECO:0000314 direct assay evidence used in manual assertion

Figure 5 shows DNA affinity

challenge
acceptableRHOCA:Q9L9062011-09-25 14:18:32 CDTGO:0016301 kinase activity (F)PMID:10347192ECO:0000314 direct assay evidence used in manual assertion
Figures 2,3
challenge
acceptableRHOCA:Q9L9062011-09-25 14:18:32 CDTGO:0000160 two-component signal transduction system (phosphorelay) (P)PMID:10347192ECO:0000314 direct assay evidence used in manual assertion
Figures 2,3
challenge
acceptableRHOCA:Q9L9062011-09-25 14:23:07 CDTGO:0046777 protein autophosphorylation (P)PMID:10347192ECO:0000314 direct assay evidence used in manual assertion

Figure 1

challenge
unacceptableECOLI:USPA2011-10-22 12:47:50 CDTGO:0006950 response to stress (P)PMID:1453957ECO:0000270 expression pattern evidence used in manual assertion

Fig. 1B and Fig. 8 show uspA expression in response to growth inhibition. "Induction is related to growth inhibition" section, p.3188, rules out uspA response to specific macronutrient starvation.

challenge
unacceptableECOLI:USPA2011-10-22 13:18:50 CDTGO:0015968 stringent response (P)PMID:18039766ECO:0000270 expression pattern evidence used in manual assertion

In paragraph 5 of section "MG1655 response to SHX treatment at 10 min.", uspA is reported to be up-regulated in the first 5 min. of stringent response from amino acid starvation. Data shown in Supp. Table 1.

challenge
acceptableHUMAN:AP3B12011-10-23 12:32:03 CDTGO:0032438 melanosome organization (P)PMID:11452004ECO:0000315 mutant phenotype evidence used in manual assertion

In Fig. 5, normal melanosomes stain for tyrosinase. HPS-2 (AP-3 beta mutant) melanosomes lack tyrosinase.

challenge
acceptableHUMAN:TYRO2011-10-23 12:35:52 CDTGO:0042470 melanosome (C)PMID:1145200ECO:0000314 direct assay evidence used in manual assertion

Fig. 5: normal melanosomes stain for Tyrosinase.

challenge

acceptable:7
unacceptable:2
requires_changes:0
flagged:0

Annotations challenged by Jcooper

StatusAuthor,GroupPageGO Term (Aspect)ReferenceEvidenceLinksPage history
unacceptableJcooper,
Team Attenuators
ECOLI:USPAGO:0015968 - stringent response (P)PMID:18039766ECO:0000270 expression pattern evidence used in manual assertionchallengeC: 2
acceptableChrispond,
Team Big Mama 50000
PSEAE:Q9HYC5GO:0003796 - lysozyme activity (F)PMID:21776080ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 1
acceptableTaustin,
Team Big Mama 50000
PSEAE:Q9I2Q1GO:0070011 - peptidase activity, acting on L-amino acid peptides (F)PMID:21776080ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 2
acceptableMkline,
Team Cheesesteak
MOUSE:GRP1GO:0032816 - positive regulation of natural killer cell activation (P)PMID:21957144ECO:0000315 mutant phenotype evidence used in manual assertionchallengeC: 1

0 annotations fixed by Jcooper