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Category:Team Jimmy Johns

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StatusPageUserDate/TimeGO Term (Aspect)ReferenceEvidenceNotesLinks
acceptableBACSU:YWCEHelioslaw, Team Jimmy Johns2011-11-18 11:23:55 CSTGO:0009847 spore germination (P)PMID:16159778ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 7

challenge
acceptableRAT:ARCAlexFrancis, Team Jimmy Johns2011-11-15 20:51:11 CSTGO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity (P)PMID:17088211ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 6

challenge
acceptableRAT:SH3G3AlexFrancis, Team Jimmy Johns2011-11-15 20:35:25 CSTGO:0005769 early endosome (C)PMID:17088211ECO:0000314 direct assay evidence used in manual assertion

Fig 3

challenge
updatedbyinstructorBACSU:APBCHelioslaw, Team Jimmy Johns2011-11-15 20:15:16 CSTGO:0045892 regulation of transcription, DNA-dependent (P)PMID:15126467ECO:0000315 mutant phenotype evidence used in manual assertion

Fig 3 and Fig 5

challenge
acceptableBACSU:HPRHelioslaw, Team Jimmy Johns2011-11-15 20:01:52 CSTGO:0006355 regulation of transcription, DNA-dependent (P)PMID:10383984ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 2

challenge
acceptableXENLA:CHK1AlexFrancis, Team Jimmy Johns2011-11-15 19:57:48 CSTGO:0006468 protein phosphorylation (P)PMID:10068474ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 3

challenge
acceptableBACSU:SINRHelioslaw, Team Jimmy Johns2011-11-15 19:46:35 CSTGO:0010629 negative regulation of gene expression (P)PMID:15661000ECO:0000315 mutant phenotype evidence used in manual assertion

Table 1

challenge
acceptableBACSU:YUTHHelioslaw, Team Jimmy Johns2011-11-04 10:54:47 CDTGO:0042601 endospore-forming forespore (C)PMID:15231775ECO:0000314 direct assay evidence used in manual assertion

Figure 6. Membrane.

challenge
acceptableBACSU:YHEDHelioslaw, Team Jimmy Johns2011-11-04 10:52:02 CDTGO:0042601 endospore-forming forespore (C)PMID:15231775ECO:0000314 direct assay evidence used in manual assertion

Figure 4 shows location of Yhe-D in forespore membrane

challenge
acceptableBACSU:YABPHelioslaw, Team Jimmy Johns2011-11-04 10:45:57 CDTGO:0042601 endospore-forming forespore (C)PMID:15231775ECO:0000314 direct assay evidence used in manual assertion

Figure 1 A shows location of yabP in the forespore membrane

challenge
acceptableBACSU:SP0JHelioslaw, Team Jimmy Johns2011-11-03 13:50:49 CDTGO:0045881 positive regulation of sporulation resulting in formation of a cellular spore (P)PMID:8071208ECO:0000316 genetic interaction evidence used in manual assertion

Figure 2 shows that spoJ, in concert with soj regulates the levels of downstream sporulation genes.

Tables 3 & 4 establish that spoJ is dependent on soj for positive regulation of sporulation.

challenge
acceptableBACSU:SOJHelioslaw, Team Jimmy Johns2011-11-03 13:44:59 CDTGO:0042174 negative regulation of sporulation resulting in formation of a cellular spore (P)PMID:8071208ECO:0000316 genetic interaction evidence used in manual assertion

Table 3

challenge
acceptableBACSU:SP0JHelioslaw, Team Jimmy Johns2011-11-03 13:34:10 CDTGO:0007059 chromosome segregation (P)PMID:8071208ECO:0000315 mutant phenotype evidence used in manual assertion

Table 5 shows accumulation in anucleate cells

challenge
acceptableMOUSE:DTBP1AlexFrancis, Team Jimmy Johns2011-11-01 20:09:08 CDTGO:0043506 regulation of JUN kinase activity (P)PMID:19094965ECO:0000315 mutant phenotype evidence used in manual assertion

Fig. 3

challenge
acceptableMOUSE:BL1S1AlexFrancis, Team Jimmy Johns2011-11-01 19:31:43 CDTGO:0005769 early endosome (C)PMID:16837549ECO:0000314 direct assay evidence used in manual assertion

Fig. 3

challenge
acceptableMOUSE:AP3S1AlexFrancis, Team Jimmy Johns2011-11-01 19:24:47 CDTGO:0016020 membrane (C)PMID:16837549ECO:0000315 mutant phenotype evidence used in manual assertion

Fig. 2

challenge
acceptableBACSU:KINAHelioslaw, Team Jimmy Johns2011-10-22 10:58:19 CDTGO:0043938 positive regulation of sporulation (P)PMID:15057450ECO:0000316 genetic interaction evidence used in manual assertion

Figure 2 shows kinase mutation effects on abrB expression, abrB is a negative regulator of sporulation

challenge
unacceptableHUMAN:AURKBAlexFrancis, Team Jimmy Johns2011-10-21 20:18:25 CDTGO:0032467 positive regulation of cytokinesis (P)PMID:12458200ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 2 a-d shows Aurora-B's role in inhibiting Vimentin and promoting cytokinesis

challenge
acceptableBACSU:ABRBHelioslaw, Team Jimmy Johns2011-10-21 11:11:28 CDTGO:0043937 regulation of sporulation (P)PMID:15057450ECO:0000316 genetic interaction evidence used in manual assertion

Table 2

challenge
acceptableBACSU:SP0EHelioslaw, Team Jimmy Johns2011-10-18 21:03:54 CDTGO:0043937 regulation of sporulation (P)PMID:15057450ECO:0000316 genetic interaction evidence used in manual assertion

Table 2 shows that mutant SpoE causes an increase in sporulation

challenge
acceptableBACSU:YABQHelioslaw, Team Jimmy Johns2011-10-18 20:36:11 CDTGO:0042601 endospore-forming forespore (C)PMID:11283287ECO:0000314 direct assay evidence used in manual assertion

Figure 5 a,b shows location of yabQ in spore membrane

challenge
acceptableBACSU:SP2QHelioslaw, Team Jimmy Johns2011-10-18 20:14:19 CDTGO:0042601 endospore-forming forespore (C)PMID:18077456ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 3 shows location of SpollQ in relation to SpollE by showing SpollQ mutant failing to relocalizing SpollE to septal membrane

challenge
acceptableBACSU:SP2EHelioslaw, Team Jimmy Johns2011-10-18 20:04:37 CDTGO:0042601 endospore-forming forespore (C)PMID:18077456ECO:0000314 direct assay evidence used in manual assertion

Figure 2. Shows SpollE is located throughout forespore membrane after polar division but concentrated at septal membrane during polar division

challenge
acceptableBACSU:DAGKHelioslaw, Team Jimmy Johns2011-10-08 10:17:51 CDTGO:0004143 diacylglycerol kinase activity (F)PMID:17535816ECO:0000314 direct assay evidence used in manual assertion

Figure 4 B,C show Dgkb kinase activity

challenge
acceptableBACSU:RSBWHelioslaw, Team Jimmy Johns2011-10-07 11:57:34 CDTGO:0016989 sigma factor antagonist activity (F)PMID:8468294ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 4 shows a large increase in the sigma b protein in rsbW mutants

challenge
acceptableBACSU:FLIYHelioslaw, Team Jimmy Johns2011-10-07 11:29:07 CDTGO:0004721 phosphoprotein phosphatase activity (F)PMID:12920116ECO:0000314 direct assay evidence used in manual assertion

Figure 5 shows Fliy activity in dephosphorylation of Chey-P

challenge
acceptableBACSU:DESKHelioslaw, Team Jimmy Johns2011-10-04 19:39:02 CDTGO:0004721 phosphoprotein phosphatase activity (F)PMID:15090506ECO:0000314 direct assay evidence used in manual assertion

Fig. 3 A shows DesKC phosphatase activity

challenge
acceptableXENLA:NOGGAlexFrancis, Team Jimmy Johns2011-10-04 19:17:13 CDTGO:0030514 negative regulation of BMP signaling pathway (P)PMID:8752214ECO:0000314 direct assay evidence used in manual assertion

Fig 1 shows noggins role in negative regulation of signal transduction.

challenge
acceptableHUMAN:NPC1AlexFrancis, Team Jimmy Johns2011-10-03 19:53:48 CDTGO:2000189 positive regulation of cholesterol homeostasis (P)PMID:9927649ECO:0000315 mutant phenotype evidence used in manual assertion

Fig 1,2 and Table 1 shows NPC-1's role in correcting the over accumulation of choloesterol in lysosomes versus the defective mutant

challenge
acceptableBACSU:RECUHelioslaw, Team Jimmy Johns2011-09-25 17:55:03 CDTGO:0006281 DNA repair (P)PMID:9642195ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 1a shows inability of mutant recU organism to survive in the presence of MMS while wild rec+ type cells are able to survive

challenge
acceptableECOLI:SKPAlexFrancis, Team Jimmy Johns2011-09-25 17:34:11 CDTGO:0022417 protein maturation by protein folding (P)PMID:9914480ECO:0000314 direct assay evidence used in manual assertion

Fig. 4C shows the maturation on PhoE in Skp serum. Table 1 shows amount of PhoE folded based on incdreasing concentraions of Skp.

challenge
acceptableBACSU:ESTAHelioslaw, Team Jimmy Johns2011-09-24 20:36:13 CDTGO:0004806 triglyceride lipase activity (F)PMID:8396026ECO:0000314 direct assay evidence used in manual assertion

Table 2 shows esterase activity of estA lipase

challenge
acceptableBACSU:YYCFHelioslaw, Team Jimmy Johns2011-09-24 11:48:40 CDTGO:0006355 regulation of transcription, DNA-dependent (P)PMID:10878122ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 6 shows direct relationship between Yycf and the expression of P1 promoter of ftszAZ operon

challenge
acceptableBACSU:CCPNHelioslaw, Team Jimmy Johns2011-09-23 12:49:51 CDTGO:0045013 carbon catabolite repression of transcription (P)PMID:15720552ECO:0000315 mutant phenotype evidence used in manual assertion

Table 1 shows that mutant CcpN more fully expressed gabB leading to the conclusion that CcpN acts as a negative regulator of gapB transcription

challenge
updatedbyinstructorMOUSE:BL1S3AlexFrancis, Team Jimmy Johns2011-09-23 12:08:12 CDTGO:0008320 protein transmembrane transporter activity (F)PMID:16837549ECO:0000315 mutant phenotype evidence used in manual assertion

Incorrect annotation, see discussion page for explanation.

challenge
acceptableBACSU:PTHPHelioslaw, Team Jimmy Johns2011-09-23 11:22:59 CDTGO:0043610 regulation of carbohydrate utilization (P)PMID:8195089ECO:0000315 mutant phenotype evidence used in manual assertion

Table 2 shows enzyme activity for gluconate kinase not repressed in mutant

challenge
acceptableHUMAN:HCSTAlexFrancis, Team Jimmy Johns2011-09-21 21:48:44 CDTGO:0006468 protein phosphorylation (P)PMID:10528161ECO:0000316 genetic interaction evidence used in manual assertion

Fig 5A Shows that KAP10 cross-linking leads to Akt (PKB/RAC) phosphrylation

Fig 5B shows that KAP10 is dependant upon PI-3 Kinase for phosphorylation activity to occur.

challenge
acceptableHUMAN:ALEXAlexFrancis, Team Jimmy Johns2011-09-21 18:58:04 CDTGO:0009966 regulation of signal transduction (P)PMID:12719376ECO:0000315 mutant phenotype evidence used in manual assertion

Figure 5A demonstrates the relationship between ALEX and XLalphas for the wild-type and mutant phenotype.

challenge

Pages in category "Team Jimmy Johns"

The following 2 pages are in this category, out of 2 total.


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